Generating neurons from human induced pluripotent stem cells(hiPSCs) overcomes the limited access to human brain tissues and greatly facilitates the research in neuroscience(Karagiannis et al., 2019).
Dystonia is a common movement disorder characterized by sustained or intermittent muscle contractions causing abnormal movements and/or postures(Keller Sarmiento and Mencacci,2021).The dystonic syndromes are classifie...Dystonia is a common movement disorder characterized by sustained or intermittent muscle contractions causing abnormal movements and/or postures(Keller Sarmiento and Mencacci,2021).The dystonic syndromes are classified as primary dystonia(dystonia is the only motor feature without tremor) and the secondary dystonia(dystonia is combined with other movement disorders,such as Parkinsonism).展开更多
基金supported by the National Institute of Neurological Diseases and Stroke,No.NINDS R21NS112910(to BD)Department of Defense(DoD)Peer Reviewed Medical Research Program(PRMRP),No.W81XWH2010186(to BD)。
文摘Generating neurons from human induced pluripotent stem cells(hiPSCs) overcomes the limited access to human brain tissues and greatly facilitates the research in neuroscience(Karagiannis et al., 2019).
基金supported by National Institute of Neurological Diseases and Stroke,No.NIH/NINDS NS112910 (to BD)Department of Defense (DoD) Peer Reviewed Medical Research Program (PRMRP) Discovery Award,No.W81XWH2010186 (to BD)。
文摘Dystonia is a common movement disorder characterized by sustained or intermittent muscle contractions causing abnormal movements and/or postures(Keller Sarmiento and Mencacci,2021).The dystonic syndromes are classified as primary dystonia(dystonia is the only motor feature without tremor) and the secondary dystonia(dystonia is combined with other movement disorders,such as Parkinsonism).
