The vertebrate liver is regarded as an organ essential to the regulation of immunity and inflammation as well as being central to the metabolism of nutrients.Here,we discuss the functions that the hepatic cecum of amp...The vertebrate liver is regarded as an organ essential to the regulation of immunity and inflammation as well as being central to the metabolism of nutrients.Here,we discuss the functions that the hepatic cecum of amphioxus plays in the regulation of immunity and inflammation,and the molecular basis of this.It is apparent that the hepatic cecum performs important roles in the immunity of amphioxus including immune surveillance,clearance of pathogens and acute phase response.Therefore,the hepatic cecum,like the vertebrate liver,is an organ functioning as a key integrator of immunity in amphioxus.展开更多
基金This work was supported by the grants of National Natural Science Foundation of China(3207051431601862).
文摘The vertebrate liver is regarded as an organ essential to the regulation of immunity and inflammation as well as being central to the metabolism of nutrients.Here,we discuss the functions that the hepatic cecum of amphioxus plays in the regulation of immunity and inflammation,and the molecular basis of this.It is apparent that the hepatic cecum performs important roles in the immunity of amphioxus including immune surveillance,clearance of pathogens and acute phase response.Therefore,the hepatic cecum,like the vertebrate liver,is an organ functioning as a key integrator of immunity in amphioxus.
