Objective: In this study, we aimed to evaluate the ocular findings in vitiligo patients and reveal any clinical feature that might suggest an association or a risk factor. Background: Very few reports in the literatur...Objective: In this study, we aimed to evaluate the ocular findings in vitiligo patients and reveal any clinical feature that might suggest an association or a risk factor. Background: Very few reports in the literature are available about the ocular findings in vitiligo and the possible associations of the ocular findings in vitiligo patients have not been studied so far. Methods: A total of 45 patients with previously documented cutaneous vitiligo were examined for ocular findings. Demographic features including age, gender, duration of vitiligo, presence of associated autoimmune diseases, type of vitiligo and the anatomical distributions of vitiligo were recorded to evaluate a possible relationship with the ocular findings. Univariate and multivariate analyses as well as cluster analysis were performed. After description of the clusters, the Mann-Whitney U-test and Fisher’s exact test were used to determine the variables. Concordance among the variables in each group was evaluated with the McNemar test. Results: Ten patients had ocular findings that included anterior segment (iris) involvement, ring-like peripapillary atrophy around the optic nerve, atrophy of pigment epithelium, focal hypopigmented spots and diffuse hypopigmentation. The presence of periorbital vitiligo was significantly related to the ocular findings. Cluster analysis revealed concordances between periorbital and genitalial localizations of vitiligo and ocular findings. Conclusion: The number of patients and the range of ocular findings in our study are insufficient to make definite conclusions but anatomical localizations, primarily periorbital and to a lesser extent genitalial vitiligo, seem to be the most probably alerting features for ocular findings.展开更多
BACKGROUND AND OBJECTIVE: The results and complications of posterior chamber i ntraocular lens (IOL) implantation by a 4-point scleral fixation technique are described. PATIENTS AND METHODS: Fifty eyes of 47 patients ...BACKGROUND AND OBJECTIVE: The results and complications of posterior chamber i ntraocular lens (IOL) implantation by a 4-point scleral fixation technique are described. PATIENTS AND METHODS: Fifty eyes of 47 patients who underwent scleral -fixated IOL implantation were retrospectively evaluated. Twenty-one (42%) ey es had a history of trauma and 29 (58%) eyes had previously undergone cataract surgery. In all cases, IOL implantation by 4-point scleral fixation was perform ed and the knots of fixation sutures were rotated and buried in the globe. The I OL position was adjusted by suture rotation for best centration. RESULTS: The me an follow-up time was 7 ±4 months. Four (8%) eyes had minimal corneal edema p reoperatively. Cystoid macular edema was noted in 2 (6.8%) eyes in the cataract surgery group and 8 (38%) eyes in the posttraumatic group. Two (9.5%) eyes in the posttraumatic group had atrophic macular changes and 1 (4.7%) had corneal scarring,which impaired vision. No complications such as knot exposure, tilting of the IOL, decentralization, or endophthalmitis were noted postoperatively. Pos toperative mean corrected visual acuity was 0.4 ±0.3 in the posttraumatic group and 0.4 ±0.2 in the cataract surgery group. CONCLUSION: The 4-point scleral f ixation technique resulted in no serious postoperative complications such as sut ure exposure and endophthalmitis. Because the knot can be rotated and buried in the globe, knot exposure is less likely to occur. This procedure ismore effectiv e than other techniques regarding IOL centralization.展开更多
文摘Objective: In this study, we aimed to evaluate the ocular findings in vitiligo patients and reveal any clinical feature that might suggest an association or a risk factor. Background: Very few reports in the literature are available about the ocular findings in vitiligo and the possible associations of the ocular findings in vitiligo patients have not been studied so far. Methods: A total of 45 patients with previously documented cutaneous vitiligo were examined for ocular findings. Demographic features including age, gender, duration of vitiligo, presence of associated autoimmune diseases, type of vitiligo and the anatomical distributions of vitiligo were recorded to evaluate a possible relationship with the ocular findings. Univariate and multivariate analyses as well as cluster analysis were performed. After description of the clusters, the Mann-Whitney U-test and Fisher’s exact test were used to determine the variables. Concordance among the variables in each group was evaluated with the McNemar test. Results: Ten patients had ocular findings that included anterior segment (iris) involvement, ring-like peripapillary atrophy around the optic nerve, atrophy of pigment epithelium, focal hypopigmented spots and diffuse hypopigmentation. The presence of periorbital vitiligo was significantly related to the ocular findings. Cluster analysis revealed concordances between periorbital and genitalial localizations of vitiligo and ocular findings. Conclusion: The number of patients and the range of ocular findings in our study are insufficient to make definite conclusions but anatomical localizations, primarily periorbital and to a lesser extent genitalial vitiligo, seem to be the most probably alerting features for ocular findings.
文摘BACKGROUND AND OBJECTIVE: The results and complications of posterior chamber i ntraocular lens (IOL) implantation by a 4-point scleral fixation technique are described. PATIENTS AND METHODS: Fifty eyes of 47 patients who underwent scleral -fixated IOL implantation were retrospectively evaluated. Twenty-one (42%) ey es had a history of trauma and 29 (58%) eyes had previously undergone cataract surgery. In all cases, IOL implantation by 4-point scleral fixation was perform ed and the knots of fixation sutures were rotated and buried in the globe. The I OL position was adjusted by suture rotation for best centration. RESULTS: The me an follow-up time was 7 ±4 months. Four (8%) eyes had minimal corneal edema p reoperatively. Cystoid macular edema was noted in 2 (6.8%) eyes in the cataract surgery group and 8 (38%) eyes in the posttraumatic group. Two (9.5%) eyes in the posttraumatic group had atrophic macular changes and 1 (4.7%) had corneal scarring,which impaired vision. No complications such as knot exposure, tilting of the IOL, decentralization, or endophthalmitis were noted postoperatively. Pos toperative mean corrected visual acuity was 0.4 ±0.3 in the posttraumatic group and 0.4 ±0.2 in the cataract surgery group. CONCLUSION: The 4-point scleral f ixation technique resulted in no serious postoperative complications such as sut ure exposure and endophthalmitis. Because the knot can be rotated and buried in the globe, knot exposure is less likely to occur. This procedure ismore effectiv e than other techniques regarding IOL centralization.
