Dear editor,Anaphylaxis and acute coronary syndromes(ACS)are discrete clinical presentations that usually present independently and are commonly treated in the emergency departments(EDs).[1]Kounis syndrome(KS)is a rar...Dear editor,Anaphylaxis and acute coronary syndromes(ACS)are discrete clinical presentations that usually present independently and are commonly treated in the emergency departments(EDs).[1]Kounis syndrome(KS)is a rare condition characterized by the coexistence of allergic reactions and ACS.KS was firstly described in detail by Kounis and Zavras in 1991 as an allergic angina syndrome.[2]The primary pathophysiological mechanism of KS is believed to be coronary artery vasospasm secondary to increased levels of infl ammatory mediators such as histamine,tryptase,platelet-activating factor,and various cytokines.[3]These inflammatory mediators are released through mast cell activation in response to a range of stimuli during episodes of allergic or hypersensitivity reactions.展开更多
文摘Dear editor,Anaphylaxis and acute coronary syndromes(ACS)are discrete clinical presentations that usually present independently and are commonly treated in the emergency departments(EDs).[1]Kounis syndrome(KS)is a rare condition characterized by the coexistence of allergic reactions and ACS.KS was firstly described in detail by Kounis and Zavras in 1991 as an allergic angina syndrome.[2]The primary pathophysiological mechanism of KS is believed to be coronary artery vasospasm secondary to increased levels of infl ammatory mediators such as histamine,tryptase,platelet-activating factor,and various cytokines.[3]These inflammatory mediators are released through mast cell activation in response to a range of stimuli during episodes of allergic or hypersensitivity reactions.
