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NOTES new frontier:Natural orifice approach to retroperitoneal disease
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作者 Pierre Allemann Silvana Perretta +2 位作者 Mitsuhiro Asakuma bernard dallemagne Jacques Marescaux 《World Journal of Gastrointestinal Surgery》 SCIE CAS 2010年第5期157-164,共8页
AIM: To develop a pure transvaginal access to the retroperitoneum, that is simple, reproducible and uses endoscopic material available on the market. METHODS: From February 2008 to April 2009, 31 pigs were operated on... AIM: To develop a pure transvaginal access to the retroperitoneum, that is simple, reproducible and uses endoscopic material available on the market. METHODS: From February 2008 to April 2009, 31 pigs were operated on, with 17 as an acute experiment and 14 with a survival protocol. The animals were placed in a supine position and a 12-mm double-channel endoscope (Karl StorzTM, Tuttlingen) was used for vision and dissection. During the same time period, the access experiment was reproduced on 3 human cadavers using material similar to that used in the animal model. RESULTS: In the animal model, 37 interventions were done on the kidney, adrenal gland and pancreas. The mean time to fashion the access was 10 min (range 5 to 20 min). No intraoperative death was observed. Two major (5%) intraoperative complications occurred: one hemorrhage on the aorta and one tearing of the right renal vein. Peritoneal laceration was encountered in 5 cases without impairing the planned task. In the survival group, good clinical outcome was observed at a mean follow-up of 3 wk (range 2 to 6 wk). In the 3 cadavers, access was performed correctly. The mean time to fashion the access was 52 min (range 40 to 60 min). All the anatomical landmarks described in the pig model were clearly identified in the same sequence. CONCLUSION: A retroperitoneal natural orifice translumenal surgical transvaginal approach is feasible in both animal and human models and allows performance of a large panel of interventions. 展开更多
关键词 Nephrectomy NATURAL ORIF ICE NATURAL ORIF ICE translumenal surgery PANCREATECTOMY RETROPERITONEUM ADRENALECTOMY
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Transgastric cholecystectomy:From the laboratory to clinical implementation
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作者 bernard dallemagne Silvana Perretta +4 位作者 Pierre Allemann Gianfranco Donatelli Mitsuhiro Asakuma Didier Mutter Jacques Marescaux 《World Journal of Gastrointestinal Surgery》 SCIE CAS 2010年第6期187-192,共6页
After the first report by Kalloo et al on transgastric peritoneoscopy in pigs,it rapidly became apparent that there was no room for an under-evaluated concept and blind adoption of an appealing(r)evolution in minimal ... After the first report by Kalloo et al on transgastric peritoneoscopy in pigs,it rapidly became apparent that there was no room for an under-evaluated concept and blind adoption of an appealing(r)evolution in minimal access surgery.Systematic experimental work became mandatory before any trans lation to the clinical setting.Choice and management of the access site,techniques of dissection,exposure,retraction and tissue approximationsealing were the basics that needed to be evaluated before considering any surgical procedure or study of the relevance of natural orifice transluminal endoscopic surgery(NOTES).After several years of testing in experimental labs,the revolutionary concept of NOTES,is now progressively being experimented on in clinical settings.In this paper the authors analyse the challenges,limitations and solutions to assess how to move from the lab to clinical implementation of transg astric endoscopic cholecystectomy. 展开更多
关键词 Flexible SURGERY CHOLECYSTECTOMY Natural ORIFICE TRANSLUMINAL ENDOSCOPIC SURGERY Minimal invasive SURGERY ENDOSCOPIC SURGERY
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