A 46- year- old Brazilian man, with initial pustular lesions, neutrophilic spongiosis and subcorneal cleavage evolved to an atypical pemphigus phenotype, with suprabasal acantholysis. Interestingly, his autoantibody p...A 46- year- old Brazilian man, with initial pustular lesions, neutrophilic spongiosis and subcorneal cleavage evolved to an atypical pemphigus phenotype, with suprabasal acantholysis. Interestingly, his autoantibody profile, tested by immunofluorescence, immunoblotting, enzyme- linked immunosorbent assay, and immunoprecipitation revealed exclusive IgG antidesmoglein 1 antibodies in all phases of the disease.展开更多
文摘A 46- year- old Brazilian man, with initial pustular lesions, neutrophilic spongiosis and subcorneal cleavage evolved to an atypical pemphigus phenotype, with suprabasal acantholysis. Interestingly, his autoantibody profile, tested by immunofluorescence, immunoblotting, enzyme- linked immunosorbent assay, and immunoprecipitation revealed exclusive IgG antidesmoglein 1 antibodies in all phases of the disease.
