Background:The hepatic artery is the only blood source nourishing the biliary duct and associated with biliary complication after liver transplantation(LT).Gastroduodenal artery(GDA)disconnection increased proper hepa...Background:The hepatic artery is the only blood source nourishing the biliary duct and associated with biliary complication after liver transplantation(LT).Gastroduodenal artery(GDA)disconnection increased proper hepatic artery flow.Whether this procedure attenuates biliary non-anastomotic stricture(NAS)is not clear.Methods:A total of 241 patients with LT were retrospectively analyzed.The patients were divided into the GDA disconnection(GDA-)and GDA preservation(GDA+)groups.Propensity score matching(PSM)was administrated to reduce bias.Logistic regression was conducted to analyze risk factors for biliary NAS before and after PSM.Postoperative complications were compared.Kaplan-Meier survival analysis and log-rank tests were performed to compare overall survival.Results:In all,99 patients(41.1%)underwent GDA disconnection,and 49(20.3%)developed NAS.Multivariate logistic regression revealed that GDA preservation(OR=2.24,95%CI:1.11-4.53;P=0.025)and model for end-stage liver disease(MELD)score>15(OR=2.14,95%CI:1.12-4.11;P=0.022)were risk factors for biliary NAS.PSM provided 66 pairs using 1:2 matching method,including 66 GDA disconnection and 99 GDA preservation patients.Multivariate logistic regression after PSM also showed that GDA preservation(OR=3.15,95%CI:1.26-7.89;P=0.014)and MELD score>15(OR=2.41,95%CI:1.08-5.36;P=0.031)were risk factors for NAS.When comparing complications between the two groups,GDA preservation was associated with a higher incidence of biliary NAS before and after PSM(P=0.031 and 0.017,respectively).In contrast,other complications including early allograft dysfunction(P=0.620),small-for-size graft syndrome(P=0.441),abdominal hemorrhage(P=1.000),major complications(Clavien-Dindo grade≥3,P=0.318),and overall survival(P=0.088)were not significantly different between the two groups.Conclusions:GDA disconnection during LT ameliorates biliary NAS incidence and may be recommended for application in clinical practice.展开更多
In order to study the distribution and evolution features of saline soil, the correlations between the groundwater depth, salinity and salinization of soil are examined through analyzing the hydrometeorological data a...In order to study the distribution and evolution features of saline soil, the correlations between the groundwater depth, salinity and salinization of soil are examined through analyzing the hydrometeorological data and distribution maps of saline soil, groundwater depth and salinity in 1957 and 2005. The results show that the area of salinization has generally decreased. The area of salinization decreases with the increasing groundwater depth, and the dynamic evolution characteristics appeared between the groundwater depth and area of salinization. The area of heavy salinization is greatest when the groundwater salinity is > 5 g/L, the area of moderate salinization is greatest when the groundwater salinity is between 2-5 g/L, the area of light salinization is greatest when the groundwater salinity is 1-2 g/L and the area of non-salinization is greatest when the groundwater salinity is <1 g/L. The area of heavy salinization was characterized with groundwater depth <2.5 m and salinity >1.8 g/L. The area of non-salinization was characterized with groundwater depth >4.0 m and salinity 0.2-1.5 g/L.展开更多
Based on analysis of the geology and hydrogeology of the alluvial fan of the Hutuo River,Hebei province of China,this paper studies the groundwater reservoir’s regulated space,storage capacity and regulated water in ...Based on analysis of the geology and hydrogeology of the alluvial fan of the Hutuo River,Hebei province of China,this paper studies the groundwater reservoir’s regulated space,storage capacity and regulated water in system.On this basis,a groundwater numerical simulation model was established.Using this model and taking into account specific regulating schemes,this paper evaluates the regulation and storage capacity of groundwater reservoirs and the effect of conjuncttive operation of surface water and groundwater.Results show that the funnel area of the study area status storage space is 12.83×108 m^3.Groundwater level after the regulation has clearly rebounded;improving groundwater supply and ensuring stable water supply in Shijiazhuang city of Hebei province,this clearly has important practical significance.展开更多
基金supported by grants from the Talent Train-ing Plan of Army Medical University(XZ-2019-505-070)the National Natural Science Foundation of China(82270687)。
文摘Background:The hepatic artery is the only blood source nourishing the biliary duct and associated with biliary complication after liver transplantation(LT).Gastroduodenal artery(GDA)disconnection increased proper hepatic artery flow.Whether this procedure attenuates biliary non-anastomotic stricture(NAS)is not clear.Methods:A total of 241 patients with LT were retrospectively analyzed.The patients were divided into the GDA disconnection(GDA-)and GDA preservation(GDA+)groups.Propensity score matching(PSM)was administrated to reduce bias.Logistic regression was conducted to analyze risk factors for biliary NAS before and after PSM.Postoperative complications were compared.Kaplan-Meier survival analysis and log-rank tests were performed to compare overall survival.Results:In all,99 patients(41.1%)underwent GDA disconnection,and 49(20.3%)developed NAS.Multivariate logistic regression revealed that GDA preservation(OR=2.24,95%CI:1.11-4.53;P=0.025)and model for end-stage liver disease(MELD)score>15(OR=2.14,95%CI:1.12-4.11;P=0.022)were risk factors for biliary NAS.PSM provided 66 pairs using 1:2 matching method,including 66 GDA disconnection and 99 GDA preservation patients.Multivariate logistic regression after PSM also showed that GDA preservation(OR=3.15,95%CI:1.26-7.89;P=0.014)and MELD score>15(OR=2.41,95%CI:1.08-5.36;P=0.031)were risk factors for NAS.When comparing complications between the two groups,GDA preservation was associated with a higher incidence of biliary NAS before and after PSM(P=0.031 and 0.017,respectively).In contrast,other complications including early allograft dysfunction(P=0.620),small-for-size graft syndrome(P=0.441),abdominal hemorrhage(P=1.000),major complications(Clavien-Dindo grade≥3,P=0.318),and overall survival(P=0.088)were not significantly different between the two groups.Conclusions:GDA disconnection during LT ameliorates biliary NAS incidence and may be recommended for application in clinical practice.
基金funded by 973 Program Special Item (2010CB428805-1)
文摘In order to study the distribution and evolution features of saline soil, the correlations between the groundwater depth, salinity and salinization of soil are examined through analyzing the hydrometeorological data and distribution maps of saline soil, groundwater depth and salinity in 1957 and 2005. The results show that the area of salinization has generally decreased. The area of salinization decreases with the increasing groundwater depth, and the dynamic evolution characteristics appeared between the groundwater depth and area of salinization. The area of heavy salinization is greatest when the groundwater salinity is > 5 g/L, the area of moderate salinization is greatest when the groundwater salinity is between 2-5 g/L, the area of light salinization is greatest when the groundwater salinity is 1-2 g/L and the area of non-salinization is greatest when the groundwater salinity is <1 g/L. The area of heavy salinization was characterized with groundwater depth <2.5 m and salinity >1.8 g/L. The area of non-salinization was characterized with groundwater depth >4.0 m and salinity 0.2-1.5 g/L.
文摘Based on analysis of the geology and hydrogeology of the alluvial fan of the Hutuo River,Hebei province of China,this paper studies the groundwater reservoir’s regulated space,storage capacity and regulated water in system.On this basis,a groundwater numerical simulation model was established.Using this model and taking into account specific regulating schemes,this paper evaluates the regulation and storage capacity of groundwater reservoirs and the effect of conjuncttive operation of surface water and groundwater.Results show that the funnel area of the study area status storage space is 12.83×108 m^3.Groundwater level after the regulation has clearly rebounded;improving groundwater supply and ensuring stable water supply in Shijiazhuang city of Hebei province,this clearly has important practical significance.