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Using statistics and mathematical modelling to understand infectious disease outbreaks:COVID-19 as an example 被引量:1
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作者 Christopher E.Overton Helena B.Stage +16 位作者 Shazaad Ahmad Jacob Curran-Sebastian Paul Dark Rajenki Das Elizabeth Fearon Timothy Felton Martyn Fyles Nick Gent Ian Hall Thomas House Hugo Lewkowicz Xiaoxi Pang Lorenzo Pellis Robert Sawko Andrew Ustianowski bindu vekaria Luke Webb 《Infectious Disease Modelling》 2020年第1期409-441,共33页
During an infectious disease outbreak,biases in the data and complexities of the underlying dynamics pose significant challenges in mathematically modelling the outbreak and designing policy.Motivated by the ongoing r... During an infectious disease outbreak,biases in the data and complexities of the underlying dynamics pose significant challenges in mathematically modelling the outbreak and designing policy.Motivated by the ongoing response to COVID-19,we provide a toolkit of statistical and mathematical models beyond the simple SIR-type differential equation models for analysing the early stages of an outbreak and assessing interventions.In particular,we focus on parameter estimation in the presence of known biases in the data,and the effect of non-pharmaceutical interventions in enclosed subpopulations,such as households and care homes.We illustrate these methods by applying them to the COVID-19 pandemic. 展开更多
关键词 COVID-19 Epidemic modelling Parameter estimation OUTBREAK BIAS INTERVENTION
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