Stable multi-electron reaction stimulated by W doping VS_(4)for enhancing magnesium storage performance

Rechargeable magnesium batteries(RMBs)hold promise for offering higher volumetric energy density and safety features,attracting increasing research interest as the next post lithium-ion batteries.Developing high performance cathode material by inducing multi-electron reaction process as well as maintaining structural stability is the key to the development and application of RMBs.Herein,multielectron reaction occurred in VS_(4)by simple W doping strategy.W doping induces valence of partial V as V^(2+)and V^(3+)in VS_(4)structure,and then stimulates electrochemical reaction involving multi-electrons in 0.5%W-V-S.The flower-like microsphere morphology as well as rich S vacancies is also modulated by W doping to neutralize structure change in such multi-electron reaction process.The fabricated 0.5%W-V-S delivers higher specific capacity(149.3 m A h g^(-1)at 50 m A g^(-1),which is 1.6 times higher than that of VS_(4)),superior rate capability(76 mA h g^(-1)at 1000 mA g^(-1)),and stable cycling performance(1500cycles with capacity retention ratio of 93.8%).Besides that,pesudocapaticance-like contribution analysis as well as galvanostatic intermittent titration technique(GITT)further confirms the enhanced Mg^(2+)storage kinetics during such multi-electron involved electrochemical reaction process.Such discovery provides new insights into the designing of multi-electron reaction process in cathode as well as neutralizing structural change during such reaction for realizing superior electrochemical performance in energy storage devices.

Can urban forests provide acoustic refuges for birds?Investigating the influence of vegetation structure and anthropogenic noise on bird sound diversity

As a crucial component of terrestrial ecosystems,urban forests play a pivotal role in protecting urban biodiversity by providing suitable habitats for acoustic spaces.Previous studies note that vegetation structure is a key factor influencing bird sounds in urban forests;hence,adjusting the frequency composition may be a strategy for birds to avoid anthropogenic noise to mask their songs.However,it is unknown whether the response mechanisms of bird vocalizations to vegetation structure remain consistent despite being impacted by anthropogenic noise.It was hypothesized that anthropogenic noise in urban forests occupies the low-frequency space of bird songs,leading to a possible reshaping of the acoustic niches of forests,and the vegetation structure of urban forests is the critical factor that shapes the acoustic space for bird vocalization.Passive acoustic monitoring in various urban forests was used to monitor natural and anthropogenic noises,and sounds were classified into three acoustic scenes(bird sounds,human sounds,and bird-human sounds)to determine interconnections between bird sounds,anthropogenic noise,and vegetation structure.Anthropogenic noise altered the acoustic niche of urban forests by intruding into the low-frequency space used by birds,and vegetation structures related to volume(trunk volume and branch volume)and density(number of branches and leaf area index)significantly impact the diversity of bird sounds.Our findings indicate that the response to low and high frequency signals to vegetation structure is distinct.By clarifying this relationship,our results contribute to understanding of how vegetation structure influences bird sounds in urban forests impacted by anthropogenic noise.

Two different autorefractors for vision screening in children and adolescents

AIM:To compare the consistency of two autorefractors(Tianle RM-9000 and Topcon KR-800)for school-age myopia children,and to provide a basis for largescale data analysis and comparison.METHODS:The refractive error in 909 subjects(age 4–18y)were measured using both autorefractors without cycloplegia.The data were analyzed using Fourier decomposition and the correlation coefficients,intraclass correlation coefficients(ICC),and Bland-Altman limits of agreement(LoA)for each parameter were calculated.RESULTS:There was a strong correlation between the spherical equivalent(SE),sphere diopter(DS),and cylinder diopter(DC)readings of the Tianle RM-9000 and those of the Topcon KR-800,with correlation coefficient values of 0.98,0.98 and 0.83 and ICC values of 0.99,0.99 and 0.93,respectively.However,the correlation coefficients and ICC values of J0 and J45 were unreliable(R=-0.004,-0.034;both ICC<0.10).Bland-Altman analysis revealed that SE,DS,and DC measured by the Tianle RM-9000 were significantly biased toward myopia compared with the Topcon KR-800,and the mean differences were-0.072,-0.026,-0.091 D,respectively(all P<0.01).The minimum absolute value of the difference within the 95%LoA for SE,DS,and DC was 0.63 D,0.50 D,0.62 D,respectively;all these values were in the clinically acceptable range.For J0 and J45,the mean differences were close to zero(P=0.43,0.84);however,the 95%LoA were relatively wide(J0 SD:0.53;95%CI:-1.00,1.10;J45 SD:0.52;95%CI:-1.00,1.00).CONCLUSION:The two autorefractors are consistent with each other,as the differences in SE,DS,and DC were within the clinically acceptable range.Readers can compare the data measured by either device in different studies and use the two devices in the same study to generate a dataset that can be analyzed together.However,the J0 and J45 vectors are unreliable and should not be used to assess astigmatism.

Analysis of Metallographic Characteristics of Aluminum Alloy for Turbocharged Impellers

In this paper, the composition, two-dimensional and three-dimensional microstructure of heat-resistant wrought aluminum alloy with strong oxidation resistance, heat resistance and easy processing are analyzed by using direct reading spectrometer, metallographic microscope and scanning electron microscope. The main alloy elements of heat-resistant forging aluminum alloy include Cu, Mg, Si, Ni and Fe. The α solid solution of each element in aluminum consists of S phase (Al2CuMg), Mg2Si phase, bright gray Al2CuNi phase and dark brown Al9FeNi phase. The distribution of each phase in the aluminum alloy is determined by the three-dimensional energy spectrum analysis of the microstructure, and the distribution of each phase in the crystal position is analyzed. The mechanism of heat resistance, easy processing type and wear resistance is obtained, which provides the theoretical basis for the development and use of heat-resistant forged aluminum alloy.

高糖溶液对腹腔镜结直肠癌术后胃肠功能恢复、炎症反应及并发症的影响

目的探讨高糖溶液对腹腔镜结直肠癌术后胃肠功能恢复、炎症反应及并发症的影响。方法选择2019年1月-2021年1月该院收治的拟行腹腔镜下结直肠癌手术的患者64例,随机分为高糖组和对照组,各32例。两组患者的腹腔镜下结直肠癌手术均由同组医师完成,高糖组术前3 h口服400 mL 12.5%葡萄糖溶液。对比两组患者术后胃肠功能恢复情况,以及围术期肿瘤坏死因子-α(TNF-α)、高迁移族蛋白B1(HMGB1)、空腹血糖(FPG)、胰岛素、内毒素、稳态模型的胰岛素抵抗指数(HOMA-IR)和胰岛素样生长因子-Ⅰ(IGF-Ⅰ)的变化,并记录两组患者术后并发症的发生情况。结果高糖组术后排气时间、首次排便时间和住院时间短于对照组,胃管留置率低于对照组,差异均有统计学意义(P<0.05)。两组患者术后1和3 d血清TNF-α和HMGB1均较术前1 d升高;高糖组术后1和3 d血清TNF-α和HMGB1均低于对照组同期水平,差异有统计学意义(P<0.05)。两组患者术后1和3 d血清FPG、胰岛素、内毒素和HOMAIR均较术前1 d升高,IGF-Ⅰ较术前1 d下降;高糖组术后1和3 d血清FPG、胰岛素、内毒素和HOMA-IR均低于对照组同期水平,IGF-Ⅰ高于对照组同期水平,差异有统计学意义(P<0.05)。高糖组术后并发症发生率为12.50%,较对照组的34.38%低,差异有统计学意义(P<0.05)。结论在腹腔镜结直肠癌根治术前口服高糖溶液,能够减轻术后炎症反应,减小血糖波动,有助于促进术后胃肠功能恢复,减少术后并发症发生。

Electrolyte Solvation Structure Design for High Voltage Zinc-Based Hybrid Batteries

Zinc(Zn)metal anodes have enticed substantial curiosity for large-scale energy storage owing to inherent safety,high specific and volumetric energy capacities of Zn metal anodes.However,the aqueous electrolyte traditionally employed in Zn batteries suffers severe decomposition due to the narrow voltage stability window.Herein,we introduce N-methylformamide(NMF)as an organic solvent and modulate the solvation structure to obtain a stable organic/aqueous hybrid electrolyte for high-voltage Zn batteries.NMF is not only extremely stable against Zn metal anodes but also reduces the free water molecule availability by creating numerous hydrogen bonds,thereby accommodating high-voltage Zn‖LiMn_(2)O_(4)batteries.The introduction of NMF prevented hydrogen evolution reaction and promoted the creation of an Frich solid electrolyte interphase,which in turn hampered dendrite growth on Zn anodes.The Zn‖LiMn_(2)O_(4)full cells delivered a high average Coulombic efficiency of 99.7%over 400 cycles.

结肠癌组织LncRNA MEG3、miR-302b-3p表达与临床分期的相关性及对手术治疗预后的指导价值探究

背景越来越多的长非编码RNA与微小RNA被发现在肿瘤的发生和发展中表达量变化显著,能够影响抑癌基因或者癌基因的表达,在癌细胞的增殖、转移中发挥了重要的作用.目的探究结肠癌组织长链非编码RNA母系印记基因3(LncRNA MEG3)、微小RNA(miR)-302b-3p表达与临床分期的相关性及对手术治疗预后的指导价值.方法选取2017-01/2022-03金华市中医医院97例结肠癌患者,观察比较不同组织LncRNA MEG3、miR-302b-3p表达,分析LncRNA MEG3、miR-302b-3p表达与临床病理特征的相关性;比较不同LncRNA MEG3、miR-302b-3p表达患者复发情况,分析结肠癌术后复发影响因素,并分析LncRNA MEG3、miR-302b-3p交互作用对结肠癌复发的影响,评价LncRNA MEG3、miR-302b-3p表达对结肠癌术后复发的预测价值.结果结肠癌组织LncRNA MEG3、miR-302b-3p表达均低于癌旁组织(P<0.05);结肠癌组织LncRNA MEG3、miR-302b-3p表达与性别、年龄、肿瘤大小无关(P>0.05),与分化程度、临床分期及淋巴结转移有关(P<0.05);结肠癌组织中LncRNA MEG3、miR-302b-3p高表达组1年内复发率低于LncRNA MEG3、miR-302b-3p低表达组(P<0.05);分化程度、临床分期、淋巴结转移均为结肠癌复发危险因素,癌组织LncRNA MEG3、miR-302b-3p表达均为结肠癌复发保护因素(P<0.05);交互作用分析显示,LncRNA MEG3、miR-302b-3p同时暴露的协同效应是LncRNA MEG3或miR-302b-3p单纯暴露产生效应的15.888倍,且二者同时暴露时,结肠癌复发风险中有56.98%归因于二者协同作用;LncRNA MEG3、miR-302b-3p预测结肠癌患者预后的曲线下面积(area under the curve,AUC)(95%CI)分别为0.720(0.620-0.807)、0.767(0.670-0.847),二者联合预测AUC(95%CI)为0.892(0.813-0.946),明显高于LncRNA MEG3、miR-302b-3p单独预测,最佳敏感度及特异度分别为92.31%、83.33%.结论结肠癌患者癌组织LncRNA MEG3、miR-302b-3p表达下调,与临床分期有关,临床检测其表达可用于明确肿瘤恶性程度、预测手术治疗预后,为临床后续治疗方案调整提供参考依据.

An fMRI Study of Words Processing in Chinese Language

Using the blood oxygen levels dependent technology of magnetic resonance imaging (BLOD-fMRI), we aimed to explore the brain activation after visual stimulation by Chinese words. In the current study, 24 healthy volunteers (12 males, 12 females, right-handed, mean age 26 ± 2 years) were prospectively included. The event related design was used in the current fMRI study when participants silently read all words appearing in the middle of the screen. Images were processed with Statistical Parametric Mapping 8 (SPM8) software, by using a general linear model (GLM). Group activations were extracted from the 2nd level group analysis with a threshold of p < 0.001, and it was shown that the main activated areas by silent reading tasks were regions involved in brain semantic processing, including middle temporal gyrus, fusiform gyrus, supplementary motor area, inferior frontal gyrus, cingulate gyrus, superior parietal lobule and inferior parietal lobule. It was also learnt that superior parietal lobule and middle temporal gyrus are related with semantic understanding, lenticular nucleus are related with semantic processing. This means, in addition to the cerebral cortex, subcortical nuclei is also very important to the processing of words in Chinese language.

抗血管药物治疗放射性脑坏死专家共识

血管内皮生长因子(vascular endothelial growth factor,VEGF)的高水平表达是放射性脑坏死(cerebral radiation necrosis,CRN)发生的重要机制。抗血管生成药物(贝伐珠单抗)通过抑制VEGF,作用于脑坏死区域周围的血管组织,减轻CRN引起的脑水肿。许多研究证实贝伐珠单抗可有效缓解脑坏死症状,改善患者的体力状况评分以及减轻影像学上脑水肿范围。抗血管治疗的疗效主要与药物作用时长相关,低剂量抗血管药物即可达到较好的治疗效果。预防是最好的治疗,CRN的发生与肿瘤相关因素和治疗相关因素相关,通过控制两方面因素,可有效预防CRN。

Effects of antiarrhythmic peptide 10 on acute ventricular arrhythmia

Objective:To observe the effects antiarrhythmic peptide 10(AAPIO) aon acute ventricular arrhythmia and the phosphorylation state of ischemic myocardium conncxin.Methods:Acute total ischemia and partial ischemia models were established by ceasing perfusion and ligating the left anterior descending coronary artery in SD rats.The effects of AAP10(1 mg/L) on the incidence rate of ischemia-induced ventricular arrhythmia were observed.The ischemic myocardium was sampled to detect total-Cx43 and NP-Cx43 by immunofluorcsecnt staining and western blotting,the total-Cx43 expression was detected through image analysis system by semi-quantitative analysis.Results:AAP10 could significantly decrease the incidence of ischemia-induced ventricular tachycardia and ventricular fibrillation.During ischemic stage,total ischemia(TI) and AAP10 total ischemia(ATI) groups were compared with partial ischemia(Pi) and AAP10 partial ischemia(API) groups.The rates of incidence for arrhythmia in the ATI and API groups(10%and 0%) were lower than those in the TI and PI groups(60%and 45%).The difference between the two groups was statistically significant(P=0.019,P=0.020).The semi-quantitative analysis results of the ischemic myocardium showed that the total-Cx43 protein expression distribution areas for TI.ATI,PI and API groups were significantly decreased compared with the control group.On the other hand,the NP-Cx43 distribution areas of TI,ATI,PI and API groups were significantly increased compared with the control group(P>0.05).AAP10 could increase the total-Cx43 expression in the ischemic area and decrease the NP-Cx43 expression.Western blot results were consistent with the results of immunofluorescence staining.Conclusions:AAP10 can significantly decrease the rate of incidence of acute ischemia-induced ventricular tachycardia and ventricular fibrillation.Acute ischemic ventricular arrhythmias may have a relationship with the decreased phosphorylation of Cx43 induced by ischemia.AAP10 may stimulate the phosphorylation of Cx43 by increasing the totai-Cx43 expression and decreasing the NP-Cx43 expression in the ischemic area,so as to decrease ventricular arrhythmia.

3D characterization of porosity and minerals of low-permeability uranium-bearing sandstone based on multi-resolution image fusion

In the process of in situ leaching of uranium,the microstructure controls and influences the flow distribution,percolation characteristics,and reaction mechanism of lixivium in the pores of reservoir rocks and directly affects the leaching of useful components.In this study,the pore throat,pore size distribution,and mineral composition of low-permeability uranium-bearing sandstone were quantitatively analyzed by high pressure mercury injection,nuclear magnetic resonance,X-ray diffraction,and wavelength-dispersive X-ray fluorescence.The distribution characteristics of pores and minerals in the samples were qualitatively analyzed using energy-dispersive scanning electron microscopy and multi-resolution CT images.Image registration with the landmarks algorithm provided by FEI Avizo was used to accurately match the CT images with different resolutions.The multi-scale and multi-mineral digital core model of low-permeability uranium-bearing sandstone is reconstructed through pore segmentation and mineral segmentation of fusion core scanning images.The results show that the pore structure of low-permeability uranium-bearing sandstone is complex and has multi-scale and multi-crossing characteristics.The intergranular pores determine the main seepage channel in the pore space,and the secondary pores have poor connectivity with other pores.Pyrite and coffinite are isolated from the connected pores and surrounded by a large number of clay minerals and ankerite cements,which increases the difficulty of uranium leaching.Clays and a large amount of ankerite cement are filled in the primary and secondary pores and pore throats of the low-permeability uraniumbearing sandstone,which significantly reduces the porosity of the movable fluid and results in low overall permeability of the cores.The multi-scale and multi-mineral digital core proposed in this study provides a basis for characterizing macroscopic and microscopic pore-throat structures and mineral distributions of low-permeability uranium-bearing sandstone and can better understand the seepage characteristics.

Development of index system for inherently safer process design using an integrated approach

With a growing population, an increasing number of petrochemical facilities are built with larger capacity and more complexity, which pose a great risk to assets, community and environment. The value of inherently safer design is recognized with time by all stakeholders, and an effective tool is needed to evaluate and compare inherent safety of alternative technologies. This study developed a safety index to evaluate existing technologies for their safety levels and guide inherently safer design. The Integrated Risk-based Safety Index(IRSI) was developed based on a comprehensive review of petrochemical processes, incident cases from Sinopec and US Chemical Safety Board, and existing safety index systems. The IRSI included all major hazards, including fire, explosion,toxic release, dust explosion, physical explosion, and runaway. Also, the integrated life cycle approach considered chemical hazards, equipment failure rates and safety measures in this risk-based index. Advanced modeling techniques, PHAST simulation and Neural Network, were used in the development of three novel sub-indices in the projects, fire, explosion and toxic release. The index system could be easily incorporated into a user friendly tool for the ease of application. A case study of hydrogen dioxide was conducted using the IRSI, which showed its capability for evaluating the safety level of process facilities.

Novel function of perforin in negatively regulating CD4^＋ T cell activation by affecting calcium signaling

Perforin 是主要从事调停的形成毛孔的蛋白质目标 T 房间死亡并且被细胞毒素的 T 淋巴细胞(CTL ) 和自然漂亮房间采用。然而，它是否也在常规 CD4+ T 房间功能起一个作用，仍然保持不清楚。这里，我们报导那在 perforin 缺乏(PKO ) 老鼠， CD4+ T 房间是响应 T 的 hyperproliferative 房间受体(TCR ) 刺激。hyperproliferation 的这个特征被改进在房间分割并且在 IL-2 分泌物伴随。看起来， perforin 缺乏不在胸腺怒气和淋巴节点影响 T 房间开发。在 vivo， perforin 缺乏导致增加的抗原特定的 T 房间增长和抗体生产。而且， PKO 老鼠更产生试验性的自体免疫的眼色素层炎。探讨分子的机制，我们发现在 TCR 刺激以后，从 PKO 老鼠的 CD4+ T 房间显示增加的细胞内部的钙流动并且随后提高抄写因素 NFAT1 的激活。我们的结果显示 perforin 在由影响 TCR 依赖的 Ca2+ 发信号调整 CD4+ T 房间激活和有免疫力的反应起一个否定作用。

Multiscale modeling of heterogeneous propellants from particle packing tograin failure using a surface-based cohesive approach

In the present work, a computational frame- work is established for multiscale modeling and analysis of solid propellants. A packing algorithm, considering the am- monium perchlorate （AP） and aluminum （A1） particles as spheres or discs is developed to match the size distribution and volume fraction of solid propellants. A homogenization theory is employed to compute the mean stress and strain of a representative volume element （RVE）. Using the mean results, a suitable size of RVE is decided. Without consider- ing the interfaces between particles and matrix, several nu- merical simulations of the relaxation of propellants are per- formed. The relaxation effect and the nonlinear mechanical behavior of propellants which are dependent on the applied loads are discussed. A new technology named surface-based cohesive behavior is proposed to describe the phenomenon of particle dewetting consisting of two ingredients： a damage initiation criterion and a damage evolution law. Several ex- amples considering contact damage behavior are computed and also nonlinear behavior caused by damaged interfaces is discussed in this paper. Furthermore the effects of the criti- cal contact stress, initial contact stiffness and contact failure distance on the damaged interface model have been studied.

Evaluation of the in vitro antimicrobial properties of ultraviolet A/riboflavin mediated crosslinking on Candida albicans and Fusarium solani

AIMTo evaluate the antimicrobial properties of ultraviolet A (UVA) (365 nm)/riboflavin against Candida albicans and Fusarium solani.

Oxygen redox chemistry in lithium-rich cathode materials for Li-ion batteries:Understanding from atomic structure to nano-engineering

Lithium-rich oxide compounds have been recognized as promising cathode materials for high performance Li-ion batteries,owing to their high specific capacity.However,it remains a great challenge to achieve the fully reversible anionic redox reactions to realize high capacity,high stability,and low voltage hysteresis for lithiumrich cathode materials.Therefore,it is critically important to comprehensively understand and control the anionic redox chemistry of lithium-rich cathode materials,including atomic structure design,and nano-scale materials engineering technologies.Herein,we summarize the recent research progress of lithium-rich cathode materials with a focus on redox chemistry.Particularly,we highlight the oxygen-based redox reactions in lithium-rich metal oxides,with critical views of designing next generation oxygen redox lithium cathode materials.Furthermore,we purposed the most promising strategies for improving the performances of lithium-rich cathode materials with a technology-spectrum from the atomic scale to nano-scale.

Effects of Piriformospora indica on the Respiration of Taxus chinensis var.mairei under Water Stress

Seedlings of Taxus chinensis var.mairei were used as experimental materials to study the adaptation of Piriformospora indica to this plant under water stress.The materials were divided into two groups,namely,with or without inoculation with P.indica.Each group was subjected to four different levels of water stress.Vitality and physiological and biochemical indexes of the roots of T.chinensis var.mairei were regularly measured.Under water stress,T.chinensis var.mairei had significantly decreased root vitality;root vitality was higher in inoculated roots than in uninoculated roots.Under intense water stress,the inoculated roots had a higher soluble sugar content than the uninoculated roots.Under water stress,T.chinensis var.mairei experienced decreased activity of aerobic respiratory metabolic enzymes.The activity of anaerobic respiratory metabolic enzymes and alcohol dehydrogenase initially increased and then decreased,whereas that of lactate dehydrogenase increased.The inoculated roots had a higher activity of respiratory metabolic enzymes than the uninoculated roots.As water stress was further intensified,the roots had significantly decreased activity of aerobic respiratory metabolic enzymes and significantly increased activity of anaerobic respiratory metabolic enzymes.The activity of respiratory metabolic enzymes decreased faster in the uninoculated roots than in the inoculated roots.This study demonstrated that Piriformospora indica plays a positive role in enhancing the antihypoxic ability of T.chinensis var.mairei,thereby alleviating plant damage due to water stress.

Trichosanthin functions as Th2-type adjuvant in induction of allergic airway inflammation

理解自然变应原导致的气喘的致病是重要的，它能排除人工的助手的干扰并且在疾病提供自然有免疫力的反应的卓见。在现在的学习，我们证明甚至没有明矾的帮助， Trichosanthin (TCS ) 能导致航线发炎。而且， TCS 显得能够代替明矾支持卵特定的航线发炎。TCS 在一个早阶段在腹膜导致了 IL-4-producing 嗜曙红血球的累积， TCS 的辅助功能被 IL-4 的阻塞在这个阶段消除。最后， TCS 从 WT 鼠标，然而并非从 IL-4-deficient 鼠标触发的嗜曙红血球被显示为卵特定的 Th2 回答的正式就职作为助手工作。我们的数据显示 TCS 是不仅变应原，而且一个 Th2 类型助手 modulating 切换对一条 Th2 小径的有免疫力的回答。事件的这链在整洁 TCS 的一个早阶段由嗜曙红血球源于 IL-4 生产。在结论， TCS 可能作为一个 Th2 助手有用，并且天生的有免疫力的房间例如嗜曙红血球，可以是一个好目标学习 Th2 反应的开始。

PSMA mimotope isolated from phage displayed peptidelibrary can induce PSMA specific immune response

INTRODUCTIONProstatecarcinomaisoneofthemostcommoncancerinmen[1,2].ThedeathratefromprostatecarcinomaisalsoincreasinginChina.Toimprovethissituation,newmarkersareneededforearlyandaccuratestagingandtreatmelltaswellasbettermeanstofollowdiseaseprogress.One...

An integrated model for predicting the flame propagation in crimped ribbon flame arresters

Crimped ribbon flame arresters are important safety devices in the chemical industry, especially for the dangerous situations. Although proper design of arresters by the numerical simulation method is promising, its reliability and accuracy are dependent upon the mathematical model. In this work, an integrated mathematical model for the microchannel in the crimped ribbon flame arresters was set up; the fluid flow behavior and the sensitivities of four chemical kinetics mechanisms of propane-air on the accuracy were analysed. It is shown that turbulence is predominant in the microchannel of the crimped ribbon flame arresters under the deflagration and detonation conditions, and a new quenching criterion for the numerical simulation is proposed. The kinetics mechanism of Mansouri et al. among the four ones is the most accurate due to the best agreement of the predicted outlet temperature at the experimental flameproof velocity with the autoignition temperature of propane-air. The species mass fraction profiles and the temperature distribution, which are too difficult to measure due to the tiny dimension of the microchannel in experiments, are captured. The fundamental insights into chemical reactions and heat loss are well portrayed. It can be concluded that the integrated mathematical model established in this work can be used as a reliable tool for modeling, selecting and designing such type of crimped ribbon flame arresters with the propane-air medium in the future.