The growing demand for substitutes of lithium chemistries in battery leads to a surge in budding novel anion-based electrochemical energy storage,where the chloride ion batteries(CIBs)take over the role.The applicatio...The growing demand for substitutes of lithium chemistries in battery leads to a surge in budding novel anion-based electrochemical energy storage,where the chloride ion batteries(CIBs)take over the role.The application of CIBs is limited by the dissolution and side reaction of chloride-based electrode materials in a liquid electrolyte.On the flipside,its solid-state electrolytes are scarcely reported due to the challenge in realizing fast Cl^(-)conductivity.The present study reports[Al(DMSO)_(6)]Cl_(3),a solid-state metal-organic material,allows chloride ion transfer.The strong Al-Cl bonds in AlCl_(3)are broken down after coordinating of Al^(3+)by ligand DMSO,and Cl^(-)in the resulting compound is weakly bound to complexions[Al(DMSO)_(6)]^(3+),which may facilitate Cl^(-)migration.By partial replacement of Cl^(-)with PF_(6)^(-),the room-temperature ionic conductivity of as-prepared electrolyte is increased by one order of magnitude from 2.172×10^(-5)S cm^(-1)to 2.012×10^(-4)S cm^(-1).When they are assembled with Ag(anode)/Ag-AgCl(cathode)electrode system,reversible electrochemical redox reactions occur on both sides,demonstrating its potential for solid-state chloride ion batteries.The strategy by weakening the bonding interaction using organic ligands between Cl^(-)and central metallic ions may provide new ideas for developing solid chloride-ion conductors.展开更多
BACKGROUND Tibial avulsion fractures of the posterior cruciate ligament(PCL)are challenging to treat and compromise knee stability and function.Traditional open surgery often requires extensive soft tissue dissection,...BACKGROUND Tibial avulsion fractures of the posterior cruciate ligament(PCL)are challenging to treat and compromise knee stability and function.Traditional open surgery often requires extensive soft tissue dissection,which may increase the risk of morbidity.In response to these concerns,arthroscopic techniques have been evolving.The aim of this study was to introduce a modified arthroscopic tech-nique utilizing an M-shaped suture fixation method for the treatment of tibial avulsion fractures of the PCL and to evaluate its outcomes through a case series.AIM To evaluate the effects of arthroscopic M-shaped suture fixation on treating tibia avulsion fractures of the PCL.METHODS We developed a modified arthroscopic M-shaped suture fixation technique for tibia avulsion fractures of the PCL.This case series included 18 patients who underwent the procedure between January 2021 and December 2022.The patients were assessed for range of motion(ROM),Lysholm score and International knee documentation committee(IKDC)score.Postoperative complications were also recorded.RESULTS The patients were followed for a mean of 13.83±2.33 months.All patients showed radiographic union.At the final follow-up,all patients had full ROM and a negative posterior drawer test.The mean Lysholm score significantly improved from 45.28±8.92 preoperatively to 91.83±4.18 at the final follow-up(P<0.001),and the mean IKDC score improved from 41.98±6.06 preoperatively to 90.89±5.32 at the final follow-up(P<0.001).CONCLUSION The modified arthroscopic M-shaped suture fixation technique is a reliable and effective treatment for tibia avulsion fractures of the PCL,with excellent fracture healing and functional recovery.展开更多
BACKGROUND Testicular pain caused by lumbar disease is uncommon in the clinic.Here we reported a case of discogenic low back pain with testicular pain that was successfully cured.CASE SUMMARY A 23-year-old male patien...BACKGROUND Testicular pain caused by lumbar disease is uncommon in the clinic.Here we reported a case of discogenic low back pain with testicular pain that was successfully cured.CASE SUMMARY A 23-year-old male patient presented to our department with chronic low back pain.Based on his clinical symptoms,signs and imaging,he was diagnosed with discogenic low back pain.Since conservative treatment for more than half a year did not significantly improve his low back pain,we decided to treat it with intradiscal methylene blue injection.During the course of surgery,we again identified the low back pain as originating from the degenerated lumbar disc by analgesic discography.Interestingly,the patient’s low back pain disappeared along with the testicular pain that had been present for more than 3 mo.After the operation,the patient’s low back pain improved,and the testicular pain did not reappear.CONCLUSION Intradiscal methylene blue injection is a convenient and effective surgical intervention for the treatment of discogenic low back pain.Lumbar disc degeneration may also be a possible clinical cause of testicular pain.Methylene blue injection in the diseased disc improved the low back pain,and the accom-panying testicular pain was successfully managed.展开更多
Objective:To investigate the intestinal flora in elderly patients with type 2 diabetes mellitus with early nephropathy.Methods:43 elderly patients with type 2 diabetes mellitus with early nephropathy(diabetic nephropa...Objective:To investigate the intestinal flora in elderly patients with type 2 diabetes mellitus with early nephropathy.Methods:43 elderly patients with type 2 diabetes mellitus with early nephropathy(diabetic nephropathy group)and 51 elderly patients with type 2 diabetes mellitus(type 2 diabetes mellitus group)admitted to our hospital from January 2021 to October 2022 were retrospectively analyzed,with 39 healthy people who underwent a physical examination in our hospital during the same period as the control group.The fecal specimens of the three groups were collected,and the 16S rDNAs of bacteria in the fecal samples were extracted,amplified,and sequenced for intestinal flora operational taxonomic unit(OTU)classification and Alpha diversity analysis.Results:(1)Intestinal flora OTUs:there were 545 intestinal flora OTUs unique to the control group,424 intestinal flora OTUs unique to diabetic nephropathy,and 321 intestinal flora OTUs unique to the type 2 diabetes group.There were 403 intestinal flora OTUs common to the control group and diabetic nephropathy group,256 intestinal flora OTUs common to the control group and type 2 diabetes group,and 298 intestinal flora OTUs common to the type 2 diabetes group and diabetic nephropathy group.235 intestinal flora OTUs were common to all 3 groups of subjects.(2)Alpha diversity:The statistical analysis indicated that there was a statistically significant difference(P<0.05)in the Alpha diversity of intestinal flora,as assessed by the Ace index and Simpson’s index,among the three subject groups.However,no statistical significance(P>0.05)was observed when comparing the Chao 1 index and Shannon index.Further observation of the Ace index and Simpson index in the three groups revealed that both the diabetic nephropathy group and the type 2 diabetes mellitus group had lower values than the control group.Conclusion:The diversity of intestinal flora decreases in elderly patients with type 2 diabetes mellitus with early nephropathy.展开更多
The China-Europe International Symposium on Software Engineering Education(CEISEE)is an international educational conference jointly initiated by Harbin Institute of Technology and Technological University Dublin in 2...The China-Europe International Symposium on Software Engineering Education(CEISEE)is an international educational conference jointly initiated by Harbin Institute of Technology and Technological University Dublin in 2005.The CEISEE is held alternately in China and Europe every year.The host cities include Harbin,Dublin in Ireland,Guangzhou,Bordeaux in France,Xi’an,Northampton in the United Kingdom,Shanghai,Milan in Italy,Chengdu,Zwikau in Germany,Shenyang,Athens in Greece,Shenzhen,Lisbon in Portugal,Beijing,and Wuhan in 2023.The conference has been gaining increasing international influence.展开更多
With the increasing penetration of wind power,large-scale integrated wind turbine brings stability and security risks to the power grid.For the aggregated modeling of large wind farms,it is crucial to consider low vol...With the increasing penetration of wind power,large-scale integrated wind turbine brings stability and security risks to the power grid.For the aggregated modeling of large wind farms,it is crucial to consider low voltage ride-through(LVRT)characteristics.However,in aggregation methods,the approximate neglect behavior is essential,which leads to inevitable errors in the aggregation process.Moreover,the lack of parameters in practice brings new challenges to the modeling of a wind farm.To address these issues,a novel cyber-physical modeling method is proposed.This method not only overcomes the aggregation problem under the black-box wind farm but also accurately realizes the aggregation error fitting according to the operation data.The simulation results reveal that the proposed method can accurately simulate the dynamic behaviors of the wind farm in various scenarios,whether in LVRT mode or normal mode.展开更多
本文运用Citespace文献计量分析软件,以《Information Systems Research》(简称ISR)期刊在1998年至2017年近20年收录的747篇文献为研究对象,从文献产出分析、国家合作网络分析、机构合作网络分析和引文网络聚类分析四个方面进行研究,研...本文运用Citespace文献计量分析软件,以《Information Systems Research》(简称ISR)期刊在1998年至2017年近20年收录的747篇文献为研究对象,从文献产出分析、国家合作网络分析、机构合作网络分析和引文网络聚类分析四个方面进行研究,研究结果表明:1) 根据文献产出分析,ISR期刊的文献产出量呈现波动性增长;2) 根据国家合作网络分析,美国在国家合作网络中是核心节点,中国需要加强国际合作,提高自身影响力;3) 在研究机构合作网络中,文献产出量前五所高校均位于美国,同时根据合作网络中心性分析,中心性在0.1以上的12所机构中,9所位于美国,中国只有香港城市大学列于其中,另外,德克萨斯大学达拉斯分校、佐治亚理工学院、新加坡国立大学和德克萨斯大学奥斯汀分校,在信息系统领域研究潜力巨大;4) 根据引文网络聚类分析,研究热点的演变可分为三个阶段:1998年至2001年期间信息系统领域研究的重心在信息系统的企业应用,2002年至2011年期间研究重心由传统的组织转移到虚拟组织的测量指标、信任和影响因素,2012年至2017年期间由电子口碑研究转向在线知识社区中的知识扩散研究。展开更多
Resilient wheels are extensively used in urban rail transit, especially for tramway systems, owing to its advantages in noise reduction. A new type of resilient wheel for a metro is designed, and its characteristics o...Resilient wheels are extensively used in urban rail transit, especially for tramway systems, owing to its advantages in noise reduction. A new type of resilient wheel for a metro is designed, and its characteristics of vibration and sound radiation, including the rolling noise of a resilient single wheel coupled with a track, are studied in this paper. A two-step research is presented. Firstly, laboratory experiments were conducted to obtain the vibration response of the designed resilient wheel under the radial excitation on its tread. Secondly, the rolling noise model of the resilient wheel coupled with a slab track used in a metro line is developed. The wheel model is based on the 3 D finite elementand boundary element methods and verified by using the experimental results obtained from the laboratory. The track vibration model is based on the wavenumber finite element method, and the track sound radiation is calculatedby using an e cient frequency-domain Rayleigh method. The interaction of the resilient wheel and the slab track is analyzed considering the measured wheel/rail roughness of the metro. The contribution of the resilient wheel to the reduction of wheel/rail system noise is analyzed. The results show that the resilient wheel can e ectively reduce the wheel/rail rolling noise by approximately 2 dB(A) to 3 dB(A), mainly because the radiated noise by the rail is reduced. In addition, the elastic modulus of the rubber has an important influence on the noise reduction of resilient wheels.展开更多
In this study, we investigated the role of the TYRO3/Akt signaling pathway in hypoxic injury to hippocampal neurons. 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay showed that hypoxia inhibited t...In this study, we investigated the role of the TYRO3/Akt signaling pathway in hypoxic injury to hippocampal neurons. 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay showed that hypoxia inhibited the proliferation and viability of hippocampal neurons. Terminal deoxynucleotidyl transferase-mediated d UTP nick end labeling assay demonstrated that hypoxia induced neuronal apoptosis in a time-dependent manner, with a greater number of apoptotic cells with longer hypoxic exposure. Immunofluorescence labeling revealed that hypoxia suppressed TYRO3 expression. Western blot assay showed that hypoxia decreased Akt phosphorylation levels in a time-dependent manner. Taken together, these findings suggest that hypoxia inhibits the proliferation of hippocampal neurons and promotes apoptosis, and that the inhibition of the TYRO3/Akt signaling pathway plays an important role in hypoxia-induced neuronal injury.展开更多
Objective To explore the interaction of Anxa2 with P-Glycoprotein (P-gp) in the migration and invasion of the multidrug-resistant (MDR) human breast cancer cell line MCF-7/ADR. Methods A pair of short hairpin RNA ...Objective To explore the interaction of Anxa2 with P-Glycoprotein (P-gp) in the migration and invasion of the multidrug-resistant (MDR) human breast cancer cell line MCF-7/ADR. Methods A pair of short hairpin RNA (shRNA) targeting P-gp was transfected into MCF-7/ADR cells, and monoclonal cell strains were screened. The expression of P-gp was detected by Western blot. Transwell chambers were used to observe the cell migration capacity and invasion ability. The interaction between P-gp and Anxa2 was examined by immunoprecipitation and immunofluorescence confocal microscopy analyses. Results P-gp expression was significantly knocked down, and there were notable decreasing trends in the migration and invasion capability of MDR breast cancer cells (P〈0.05). There was a close interaction between Anxa2 and P-gp. Conclusions MCF-7/ADR is an MDR human breast cancer cell line with high migration and invasion abilities. The knockdown of P-gp notably impaired the migration and invasion abilities of the tumor cells. The interaction of Anxa2 with P-pg may play an important role in time enhanced invasiveness of MDR human breast cancer cells.展开更多
In order to estimate vehicular queue length at signalized intersections accurately and overcome the shortcomings and restrictions of existing studies especially those based on shockwave theory,a new methodology is pre...In order to estimate vehicular queue length at signalized intersections accurately and overcome the shortcomings and restrictions of existing studies especially those based on shockwave theory,a new methodology is presented for estimating vehicular queue length using data from both point detectors and probe vehicles. The methodology applies the shockwave theory to model queue evolution over time and space. Using probe vehicle locations and times as well as point detector measured traffic states,analytical formulations for calculating the maximum and minimum( residual) queue length are developed. The proposed methodology is verified using ground truth data collected from numerical experiments conducted in Shanghai,China. It is found that the methodology has a mean absolute percentage error of 17. 09%,which is reasonably effective in estimating the queue length at traffic signalized intersections. Limitations of the proposed models and algorithms are also discussed in the paper.展开更多
Thermal self-compressing bonding(TSCB) is a new solid-state bonding method pioneered by the authors. With electron beam as the non-melted heat source, previous experimental study performed on titanium alloys has prove...Thermal self-compressing bonding(TSCB) is a new solid-state bonding method pioneered by the authors. With electron beam as the non-melted heat source, previous experimental study performed on titanium alloys has proved the feasibility of TSCB. However, the thermal stress–strain process during bonding, which is of very important significance in revealing the mechanism of TSCB, was not analysed. In this paper, finite element analysis method is adopted to numerically study the thermal elasto-plastic stress–strain cycle of thermal self-compressing bonding. It is found that due to the localized heating, a non-uniform temperature distribution is formed during bonding, with the highest temperature existed on the bond interface. The expansion of high temperature materials adjacent to the bond interface are restrained by surrounding cool materials and rigid restraints, and thus an internal elasto-plastic stress–strain field is developed by itself which makes the bond interface subjected to thermal compressive action. This thermal self-compressing action combined with the high temperature on the bond interface promotes the atom diffusion across the bond interface to produce solid-state joints. Due to the relatively large plastic deformation, rigid restraint TSCB obtains sound joints in relatively short time compared to diffusion bonding.展开更多
CuO nanoparticle was synthesized via wet chemical method and was characterized diffraction (XRD), nitrogen adsorption-desorption, and scanning electron microscopy (SEM) by X-ray Catalytic oxidation of cumene with ...CuO nanoparticle was synthesized via wet chemical method and was characterized diffraction (XRD), nitrogen adsorption-desorption, and scanning electron microscopy (SEM) by X-ray Catalytic oxidation of cumene with molecular oxygen was studied over CuO nanoparticle. The catalysts showed markedly higher activities as compared to CuO prepared by conventional method, CuO/Al2O3, or homogeneous copper catalyst under comparable reaction conditions. The cumene conversion, cumene hydroperoxide (CHP) yield, and selectivity using 0.25 g CuO nanoparticle catalyst and 0.1 mol cumene at 358 K for 7 h were 44.2%, 41.2% and 93.2%, respectively. The catalyst can be recycled. After 6 recycled experiments, no loss of catalytic activity was observed.展开更多
Axial piston pump is fluid-solid coupling mechanical equipment. Its vibration characteristic is compli-cated when working. This paper uses the characteristic line-fast Fourier transform method (MOC - FFT) in theplun...Axial piston pump is fluid-solid coupling mechanical equipment. Its vibration characteristic is compli-cated when working. This paper uses the characteristic line-fast Fourier transform method (MOC - FFT) in theplunger pump to study vibration characteristics caused by fluid-solid coupling. Using the MOC to solve the fluid-solid interaction' s (FSI) partial differential equations ( 1 ), then the vibration characteristics of pipeline system intime domain can be achieved. Using the fast Fourier transform method, the natural frequencies of the piping sys-tem can be obtained. It has the advantage of characteristic line method for the coupling vibration model is clear,easy to calculate; And using the method of fast Fourier transform the vibration characteristics to the frequency do-main. According to study the vibration characteristics in the frequency domain, this paper achieved the frequencywhich the type of A10V pump should be avoided when working and change rules of the angle of swash plate, pres-sure and the speed of rotation how to affect the intensive frequency vibration spectrum which is caused by the FSI.展开更多
Light is the major source of energy for plants and as such has a profound effect on plant growth and development.Red and blue lights have been considered to best drive photosynthetic metabolism and are beneficial for ...Light is the major source of energy for plants and as such has a profound effect on plant growth and development.Red and blue lights have been considered to best drive photosynthetic metabolism and are beneficial for plant growth and development,and green light was seen as a signal to slow down or stop.In this study,Arabidopsis thaliana(Arabidopsis)was used to investigate the effects of red,blue and green lights on the growth and development of plants from seed germination to seeding.Results demonstrated that red light showed a promotion effect but blue light a prohibition one in most stages except for the flowering time in which the effect of each light was just reversed.When mixed with red or blue light,green light generally at least partially cancelled out the effects caused by each of them.Results also showed that the same number of photons the plant received could cause different effects and choosing the right combination of different color of lights is essential in both promoting the growth and development of plants and reducing the energy consumption of lighting in plant factory.展开更多
Oilseed flax is one of the most important oil crops in China.With the improvement of people's living standards and the deepening knowledge of the nutritional value of oilseed flax,the demand and economic value of ...Oilseed flax is one of the most important oil crops in China.With the improvement of people's living standards and the deepening knowledge of the nutritional value of oilseed flax,the demand and economic value of oilseed flax are increasing,and the cultivated area in China is expanding.However,the grain yield of oilseed flax is lower than other oil crops.It varies significantly from year to year,combined with a lower degree of mechanization,which has greatly limited the healthy development of the flax industry.Some of the effects of agronomic measures on productivity and water use efficiency of oilseed flax are reviewed in this paper.The major agronomic strategies for the productivity of oilseed flax were presented based on fertilization,plant density,irrigation,cropping pattern and weed control.Future research should investigate the effect of silicon and potassium fertilizers on the mechanism of lodging resistance of oilseed flax,the effects of diversified cropping systems(strip intercropping and crop rotation)on high and stable productivity and efficient utilization of resources.展开更多
基金supported by the Czech Science Foundation(GACR No.2016124J)supported by the grant of Specific university researchgrant No.A2_FCHT_2022_056
文摘The growing demand for substitutes of lithium chemistries in battery leads to a surge in budding novel anion-based electrochemical energy storage,where the chloride ion batteries(CIBs)take over the role.The application of CIBs is limited by the dissolution and side reaction of chloride-based electrode materials in a liquid electrolyte.On the flipside,its solid-state electrolytes are scarcely reported due to the challenge in realizing fast Cl^(-)conductivity.The present study reports[Al(DMSO)_(6)]Cl_(3),a solid-state metal-organic material,allows chloride ion transfer.The strong Al-Cl bonds in AlCl_(3)are broken down after coordinating of Al^(3+)by ligand DMSO,and Cl^(-)in the resulting compound is weakly bound to complexions[Al(DMSO)_(6)]^(3+),which may facilitate Cl^(-)migration.By partial replacement of Cl^(-)with PF_(6)^(-),the room-temperature ionic conductivity of as-prepared electrolyte is increased by one order of magnitude from 2.172×10^(-5)S cm^(-1)to 2.012×10^(-4)S cm^(-1).When they are assembled with Ag(anode)/Ag-AgCl(cathode)electrode system,reversible electrochemical redox reactions occur on both sides,demonstrating its potential for solid-state chloride ion batteries.The strategy by weakening the bonding interaction using organic ligands between Cl^(-)and central metallic ions may provide new ideas for developing solid chloride-ion conductors.
文摘BACKGROUND Tibial avulsion fractures of the posterior cruciate ligament(PCL)are challenging to treat and compromise knee stability and function.Traditional open surgery often requires extensive soft tissue dissection,which may increase the risk of morbidity.In response to these concerns,arthroscopic techniques have been evolving.The aim of this study was to introduce a modified arthroscopic tech-nique utilizing an M-shaped suture fixation method for the treatment of tibial avulsion fractures of the PCL and to evaluate its outcomes through a case series.AIM To evaluate the effects of arthroscopic M-shaped suture fixation on treating tibia avulsion fractures of the PCL.METHODS We developed a modified arthroscopic M-shaped suture fixation technique for tibia avulsion fractures of the PCL.This case series included 18 patients who underwent the procedure between January 2021 and December 2022.The patients were assessed for range of motion(ROM),Lysholm score and International knee documentation committee(IKDC)score.Postoperative complications were also recorded.RESULTS The patients were followed for a mean of 13.83±2.33 months.All patients showed radiographic union.At the final follow-up,all patients had full ROM and a negative posterior drawer test.The mean Lysholm score significantly improved from 45.28±8.92 preoperatively to 91.83±4.18 at the final follow-up(P<0.001),and the mean IKDC score improved from 41.98±6.06 preoperatively to 90.89±5.32 at the final follow-up(P<0.001).CONCLUSION The modified arthroscopic M-shaped suture fixation technique is a reliable and effective treatment for tibia avulsion fractures of the PCL,with excellent fracture healing and functional recovery.
文摘BACKGROUND Testicular pain caused by lumbar disease is uncommon in the clinic.Here we reported a case of discogenic low back pain with testicular pain that was successfully cured.CASE SUMMARY A 23-year-old male patient presented to our department with chronic low back pain.Based on his clinical symptoms,signs and imaging,he was diagnosed with discogenic low back pain.Since conservative treatment for more than half a year did not significantly improve his low back pain,we decided to treat it with intradiscal methylene blue injection.During the course of surgery,we again identified the low back pain as originating from the degenerated lumbar disc by analgesic discography.Interestingly,the patient’s low back pain disappeared along with the testicular pain that had been present for more than 3 mo.After the operation,the patient’s low back pain improved,and the testicular pain did not reappear.CONCLUSION Intradiscal methylene blue injection is a convenient and effective surgical intervention for the treatment of discogenic low back pain.Lumbar disc degeneration may also be a possible clinical cause of testicular pain.Methylene blue injection in the diseased disc improved the low back pain,and the accom-panying testicular pain was successfully managed.
文摘Objective:To investigate the intestinal flora in elderly patients with type 2 diabetes mellitus with early nephropathy.Methods:43 elderly patients with type 2 diabetes mellitus with early nephropathy(diabetic nephropathy group)and 51 elderly patients with type 2 diabetes mellitus(type 2 diabetes mellitus group)admitted to our hospital from January 2021 to October 2022 were retrospectively analyzed,with 39 healthy people who underwent a physical examination in our hospital during the same period as the control group.The fecal specimens of the three groups were collected,and the 16S rDNAs of bacteria in the fecal samples were extracted,amplified,and sequenced for intestinal flora operational taxonomic unit(OTU)classification and Alpha diversity analysis.Results:(1)Intestinal flora OTUs:there were 545 intestinal flora OTUs unique to the control group,424 intestinal flora OTUs unique to diabetic nephropathy,and 321 intestinal flora OTUs unique to the type 2 diabetes group.There were 403 intestinal flora OTUs common to the control group and diabetic nephropathy group,256 intestinal flora OTUs common to the control group and type 2 diabetes group,and 298 intestinal flora OTUs common to the type 2 diabetes group and diabetic nephropathy group.235 intestinal flora OTUs were common to all 3 groups of subjects.(2)Alpha diversity:The statistical analysis indicated that there was a statistically significant difference(P<0.05)in the Alpha diversity of intestinal flora,as assessed by the Ace index and Simpson’s index,among the three subject groups.However,no statistical significance(P>0.05)was observed when comparing the Chao 1 index and Shannon index.Further observation of the Ace index and Simpson index in the three groups revealed that both the diabetic nephropathy group and the type 2 diabetes mellitus group had lower values than the control group.Conclusion:The diversity of intestinal flora decreases in elderly patients with type 2 diabetes mellitus with early nephropathy.
文摘The China-Europe International Symposium on Software Engineering Education(CEISEE)is an international educational conference jointly initiated by Harbin Institute of Technology and Technological University Dublin in 2005.The CEISEE is held alternately in China and Europe every year.The host cities include Harbin,Dublin in Ireland,Guangzhou,Bordeaux in France,Xi’an,Northampton in the United Kingdom,Shanghai,Milan in Italy,Chengdu,Zwikau in Germany,Shenyang,Athens in Greece,Shenzhen,Lisbon in Portugal,Beijing,and Wuhan in 2023.The conference has been gaining increasing international influence.
基金supported by Liaoning Education Department of Scientific Research Project LQGD2020002。
文摘With the increasing penetration of wind power,large-scale integrated wind turbine brings stability and security risks to the power grid.For the aggregated modeling of large wind farms,it is crucial to consider low voltage ride-through(LVRT)characteristics.However,in aggregation methods,the approximate neglect behavior is essential,which leads to inevitable errors in the aggregation process.Moreover,the lack of parameters in practice brings new challenges to the modeling of a wind farm.To address these issues,a novel cyber-physical modeling method is proposed.This method not only overcomes the aggregation problem under the black-box wind farm but also accurately realizes the aggregation error fitting according to the operation data.The simulation results reveal that the proposed method can accurately simulate the dynamic behaviors of the wind farm in various scenarios,whether in LVRT mode or normal mode.
基金the support from Human Resources and Social Security Department of Hebei Province, which identified the first author as senior visiting scholarthe Service Center for Experts and Scholars of Hebei Province for financial support, and the College of Business, Dublin Institute of Technology for providing a research place to the first author
基金Supported by National Key R&D Program of China(Grant No.2017YFB1201103-08)National Nature Science Foundation of China(Grant No.51605318)
文摘Resilient wheels are extensively used in urban rail transit, especially for tramway systems, owing to its advantages in noise reduction. A new type of resilient wheel for a metro is designed, and its characteristics of vibration and sound radiation, including the rolling noise of a resilient single wheel coupled with a track, are studied in this paper. A two-step research is presented. Firstly, laboratory experiments were conducted to obtain the vibration response of the designed resilient wheel under the radial excitation on its tread. Secondly, the rolling noise model of the resilient wheel coupled with a slab track used in a metro line is developed. The wheel model is based on the 3 D finite elementand boundary element methods and verified by using the experimental results obtained from the laboratory. The track vibration model is based on the wavenumber finite element method, and the track sound radiation is calculatedby using an e cient frequency-domain Rayleigh method. The interaction of the resilient wheel and the slab track is analyzed considering the measured wheel/rail roughness of the metro. The contribution of the resilient wheel to the reduction of wheel/rail system noise is analyzed. The results show that the resilient wheel can e ectively reduce the wheel/rail rolling noise by approximately 2 dB(A) to 3 dB(A), mainly because the radiated noise by the rail is reduced. In addition, the elastic modulus of the rubber has an important influence on the noise reduction of resilient wheels.
基金supported by the National Natural Science Foundation of China,No.81001541the Natural Science Foundation of Fujian Province of China,No.2013J01331
文摘In this study, we investigated the role of the TYRO3/Akt signaling pathway in hypoxic injury to hippocampal neurons. 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay showed that hypoxia inhibited the proliferation and viability of hippocampal neurons. Terminal deoxynucleotidyl transferase-mediated d UTP nick end labeling assay demonstrated that hypoxia induced neuronal apoptosis in a time-dependent manner, with a greater number of apoptotic cells with longer hypoxic exposure. Immunofluorescence labeling revealed that hypoxia suppressed TYRO3 expression. Western blot assay showed that hypoxia decreased Akt phosphorylation levels in a time-dependent manner. Taken together, these findings suggest that hypoxia inhibits the proliferation of hippocampal neurons and promotes apoptosis, and that the inhibition of the TYRO3/Akt signaling pathway plays an important role in hypoxia-induced neuronal injury.
基金supported by grants from the National Natural Science Foundation of China(No.81071731 and 81001188)the Changjiang Scholars and Innovative Research Team(No.IRT1076)the Tianjin Higher Education Science & Technology Fund Planning Project(No.20100120)
文摘Objective To explore the interaction of Anxa2 with P-Glycoprotein (P-gp) in the migration and invasion of the multidrug-resistant (MDR) human breast cancer cell line MCF-7/ADR. Methods A pair of short hairpin RNA (shRNA) targeting P-gp was transfected into MCF-7/ADR cells, and monoclonal cell strains were screened. The expression of P-gp was detected by Western blot. Transwell chambers were used to observe the cell migration capacity and invasion ability. The interaction between P-gp and Anxa2 was examined by immunoprecipitation and immunofluorescence confocal microscopy analyses. Results P-gp expression was significantly knocked down, and there were notable decreasing trends in the migration and invasion capability of MDR breast cancer cells (P〈0.05). There was a close interaction between Anxa2 and P-gp. Conclusions MCF-7/ADR is an MDR human breast cancer cell line with high migration and invasion abilities. The knockdown of P-gp notably impaired the migration and invasion abilities of the tumor cells. The interaction of Anxa2 with P-pg may play an important role in time enhanced invasiveness of MDR human breast cancer cells.
基金Sponsored by the National Natural Science Foundation of China(Grant No.51138003)
文摘In order to estimate vehicular queue length at signalized intersections accurately and overcome the shortcomings and restrictions of existing studies especially those based on shockwave theory,a new methodology is presented for estimating vehicular queue length using data from both point detectors and probe vehicles. The methodology applies the shockwave theory to model queue evolution over time and space. Using probe vehicle locations and times as well as point detector measured traffic states,analytical formulations for calculating the maximum and minimum( residual) queue length are developed. The proposed methodology is verified using ground truth data collected from numerical experiments conducted in Shanghai,China. It is found that the methodology has a mean absolute percentage error of 17. 09%,which is reasonably effective in estimating the queue length at traffic signalized intersections. Limitations of the proposed models and algorithms are also discussed in the paper.
基金Supported by National Natural Science Foundation of China(Grant No.51705491)
文摘Thermal self-compressing bonding(TSCB) is a new solid-state bonding method pioneered by the authors. With electron beam as the non-melted heat source, previous experimental study performed on titanium alloys has proved the feasibility of TSCB. However, the thermal stress–strain process during bonding, which is of very important significance in revealing the mechanism of TSCB, was not analysed. In this paper, finite element analysis method is adopted to numerically study the thermal elasto-plastic stress–strain cycle of thermal self-compressing bonding. It is found that due to the localized heating, a non-uniform temperature distribution is formed during bonding, with the highest temperature existed on the bond interface. The expansion of high temperature materials adjacent to the bond interface are restrained by surrounding cool materials and rigid restraints, and thus an internal elasto-plastic stress–strain field is developed by itself which makes the bond interface subjected to thermal compressive action. This thermal self-compressing action combined with the high temperature on the bond interface promotes the atom diffusion across the bond interface to produce solid-state joints. Due to the relatively large plastic deformation, rigid restraint TSCB obtains sound joints in relatively short time compared to diffusion bonding.
基金This work is supported by the Natural Science Foundation of South China University of China(143E5041280)
文摘CuO nanoparticle was synthesized via wet chemical method and was characterized diffraction (XRD), nitrogen adsorption-desorption, and scanning electron microscopy (SEM) by X-ray Catalytic oxidation of cumene with molecular oxygen was studied over CuO nanoparticle. The catalysts showed markedly higher activities as compared to CuO prepared by conventional method, CuO/Al2O3, or homogeneous copper catalyst under comparable reaction conditions. The cumene conversion, cumene hydroperoxide (CHP) yield, and selectivity using 0.25 g CuO nanoparticle catalyst and 0.1 mol cumene at 358 K for 7 h were 44.2%, 41.2% and 93.2%, respectively. The catalyst can be recycled. After 6 recycled experiments, no loss of catalytic activity was observed.
基金supported by Natural Science Foundation of Shanxi Province, Project ( No. 2014011024-2)
文摘Axial piston pump is fluid-solid coupling mechanical equipment. Its vibration characteristic is compli-cated when working. This paper uses the characteristic line-fast Fourier transform method (MOC - FFT) in theplunger pump to study vibration characteristics caused by fluid-solid coupling. Using the MOC to solve the fluid-solid interaction' s (FSI) partial differential equations ( 1 ), then the vibration characteristics of pipeline system intime domain can be achieved. Using the fast Fourier transform method, the natural frequencies of the piping sys-tem can be obtained. It has the advantage of characteristic line method for the coupling vibration model is clear,easy to calculate; And using the method of fast Fourier transform the vibration characteristics to the frequency do-main. According to study the vibration characteristics in the frequency domain, this paper achieved the frequencywhich the type of A10V pump should be avoided when working and change rules of the angle of swash plate, pres-sure and the speed of rotation how to affect the intensive frequency vibration spectrum which is caused by the FSI.
基金This study was supported by the National Natural Science Foundation of China(grant no.81701087)the Natural Science Foundation of Fujian Province(grant no.2018J01610)+1 种基金the Fuzhou Science and Technology Planning Project(grant no.2018-G-53)the Outstanding Youth Fund of Fujian Agriculture and Forestry University(XJQ201820).
文摘Light is the major source of energy for plants and as such has a profound effect on plant growth and development.Red and blue lights have been considered to best drive photosynthetic metabolism and are beneficial for plant growth and development,and green light was seen as a signal to slow down or stop.In this study,Arabidopsis thaliana(Arabidopsis)was used to investigate the effects of red,blue and green lights on the growth and development of plants from seed germination to seeding.Results demonstrated that red light showed a promotion effect but blue light a prohibition one in most stages except for the flowering time in which the effect of each light was just reversed.When mixed with red or blue light,green light generally at least partially cancelled out the effects caused by each of them.Results also showed that the same number of photons the plant received could cause different effects and choosing the right combination of different color of lights is essential in both promoting the growth and development of plants and reducing the energy consumption of lighting in plant factory.
基金funded by the Research Program Sponsored by Gansu Provincial Key Laboratory of Arid Land Crop Science,Gansu Agricultural University(GSCS-2020-Z6)the China Agriculture Research System of MOF and MARA(CARS-14-1-16)+2 种基金the National Natural Science Foundation of China(31760363 and 32060437)the Fuxi Outstanding Talent Cultivation Plan of Gansu Agriculture University(Gaufx-02J05)the Education Science and Technology Innovation Project of Gansu Province(2021CXZX-366)。
文摘Oilseed flax is one of the most important oil crops in China.With the improvement of people's living standards and the deepening knowledge of the nutritional value of oilseed flax,the demand and economic value of oilseed flax are increasing,and the cultivated area in China is expanding.However,the grain yield of oilseed flax is lower than other oil crops.It varies significantly from year to year,combined with a lower degree of mechanization,which has greatly limited the healthy development of the flax industry.Some of the effects of agronomic measures on productivity and water use efficiency of oilseed flax are reviewed in this paper.The major agronomic strategies for the productivity of oilseed flax were presented based on fertilization,plant density,irrigation,cropping pattern and weed control.Future research should investigate the effect of silicon and potassium fertilizers on the mechanism of lodging resistance of oilseed flax,the effects of diversified cropping systems(strip intercropping and crop rotation)on high and stable productivity and efficient utilization of resources.