Breast cancer is the first cancer of women in the world and in France.In very elderly patients,the treatment options are often very limited.Neoadjuvant hormone therapy has shown similar or even better results than che...Breast cancer is the first cancer of women in the world and in France.In very elderly patients,the treatment options are often very limited.Neoadjuvant hormone therapy has shown similar or even better results than chemotherapy.This is why we decided to evaluate the clinical response following exclusive hormonal therapy and the 5,then 10 years survival in these very elderly women.This was a retrospective,longitudinal cohort-type study with descriptive and analytical purposes.The study population consisted of 59 patients,with an average age of 85 years.Fifteen(15,25%)of our patients had a complete clinical response after two years of treatment,16(27%)a partial clinical response,23(39%)lesion stabilization and 5(9%)cancer progression.The presence of metastasis at diagnosis increased the risk of cancer progression by 2.84.Overall 5-year survival was 72.5%,and breast cancer mortality 5.88%.The 10-year survival was 27.5%and breast cancer mortality 15%.In the age group 85 and over increased the risk of death by 3.25 in the first 10 years of treatment.The clinical response after 2 years was marked by a low rate of cancer progression.Mortality over 5 and 10 years was mostly related to patient comorbidities.展开更多
There are many zones of high prevalence of hepatitis B like Cameroon(10%).Mother to child transmission of hepatitis B is the most common mode of transmission in high prevalence area.Its prevention is assured by the he...There are many zones of high prevalence of hepatitis B like Cameroon(10%).Mother to child transmission of hepatitis B is the most common mode of transmission in high prevalence area.Its prevention is assured by the health care staff in charge of pregnant women.We therefore used to assess the level of competence(skills levels)of obstetricians regarding hepatitis B in West region of Cameroon.This was a cross-sectional analytical KAP study.The recruitment took place in 11 hospitals in 5 major departments of West region of Cameroon.The sampling was consecutive and comprehensive.The population was constituted of 148 participants with a sex ratio of 0.51.The mean age was 34 years.The population consisted of 50 physicians(33.78%),61 nurses(41.22%),and 37 auxiliary staff(25%).Only 4%had a good skills level,55%had an average skills level,and 41%had an insufficient level.The Skills level was influenced by gender,occupation,seniority in the occupation.The skills level of health care workers was average and insufficient for most.This does not allow them to effectively fight against the mother to child transmission of hepatitis B virus in Cameroon.展开更多
文摘Breast cancer is the first cancer of women in the world and in France.In very elderly patients,the treatment options are often very limited.Neoadjuvant hormone therapy has shown similar or even better results than chemotherapy.This is why we decided to evaluate the clinical response following exclusive hormonal therapy and the 5,then 10 years survival in these very elderly women.This was a retrospective,longitudinal cohort-type study with descriptive and analytical purposes.The study population consisted of 59 patients,with an average age of 85 years.Fifteen(15,25%)of our patients had a complete clinical response after two years of treatment,16(27%)a partial clinical response,23(39%)lesion stabilization and 5(9%)cancer progression.The presence of metastasis at diagnosis increased the risk of cancer progression by 2.84.Overall 5-year survival was 72.5%,and breast cancer mortality 5.88%.The 10-year survival was 27.5%and breast cancer mortality 15%.In the age group 85 and over increased the risk of death by 3.25 in the first 10 years of treatment.The clinical response after 2 years was marked by a low rate of cancer progression.Mortality over 5 and 10 years was mostly related to patient comorbidities.
文摘There are many zones of high prevalence of hepatitis B like Cameroon(10%).Mother to child transmission of hepatitis B is the most common mode of transmission in high prevalence area.Its prevention is assured by the health care staff in charge of pregnant women.We therefore used to assess the level of competence(skills levels)of obstetricians regarding hepatitis B in West region of Cameroon.This was a cross-sectional analytical KAP study.The recruitment took place in 11 hospitals in 5 major departments of West region of Cameroon.The sampling was consecutive and comprehensive.The population was constituted of 148 participants with a sex ratio of 0.51.The mean age was 34 years.The population consisted of 50 physicians(33.78%),61 nurses(41.22%),and 37 auxiliary staff(25%).Only 4%had a good skills level,55%had an average skills level,and 41%had an insufficient level.The Skills level was influenced by gender,occupation,seniority in the occupation.The skills level of health care workers was average and insufficient for most.This does not allow them to effectively fight against the mother to child transmission of hepatitis B virus in Cameroon.
