A chiral cobalt pincer complex,when combined with an achiral electron-rich mono-phosphine ligand,catalyzes efficient asymmetric hydrogenation of a wide range of aryl ketones,affording chiral alcohols with high yields ...A chiral cobalt pincer complex,when combined with an achiral electron-rich mono-phosphine ligand,catalyzes efficient asymmetric hydrogenation of a wide range of aryl ketones,affording chiral alcohols with high yields and moderate to excellent enantioselectivities(29 examples,up to 93%ee).Notably,the achiral mono-phosphine ligand shows a remarkable effect on the enantioselectivity of the reaction.展开更多
基金financial support of the National Natural Science Foundation of China(No.21672133)。
文摘A chiral cobalt pincer complex,when combined with an achiral electron-rich mono-phosphine ligand,catalyzes efficient asymmetric hydrogenation of a wide range of aryl ketones,affording chiral alcohols with high yields and moderate to excellent enantioselectivities(29 examples,up to 93%ee).Notably,the achiral mono-phosphine ligand shows a remarkable effect on the enantioselectivity of the reaction.
