A Study on the Dynamic Adjustment of Pressure Relief Gas Drainage Drilling in Mined-Out Areas

With the development of coal mine equipment mechanization, the wide application of “hole instead of roadway” technology greatly reduces the cost of gas control engineering, but puts forward higher requirements for the effect of gas drainage. At present, the drainage effect of coal mine inspection boreholes is mainly evaluated by the drilling field, but the flow rate and gas concentration of each borehole in the drilling field are not the same, which causes the gas drainage effect not to be correctly mastered. In the present study, the pressure relief drilling in the goaf of the working face of a typical multi-coal seam group high gas outburst mining area was taken as the research object. Through the newly developed portable drilling inspection device, the pure amount of drilling drainage was investigated, and the drilling design was dynamically adjusted. The enhancement of the goaf pressure relief gas control effect ensures the gas safety of the mining face. At the same time, this improves the gas extraction rate and reduces the emission of greenhouse gases. If the data from the borehole investigation can be transmitted in real time and analyzed in big data, the optimal extraction negative pressure can be predicted through a regression algorithm. Under the control of the negative pressure of each borehole by the actuator, the extraction system can have the function of intelligent judgment.

Expression and detection significance of immune markers and inflammatory factors in peripheral blood of children with bronchial asthma

Objective: To explore the expression and detection significance of immune markers and inflammatory factors in peripheral blood of children with bronchial asthma. Method: A total of 86 cases of children with bronchial asthma admitted in our hospital from March 2015 to January 2017 were selected as observation group, and 86 cases of healthy children were selected as control group. The level of peripheral blood immunity included CD3+, CD4+, CD8+, CD4+ /CD8+, Th1, Th2, Th1/Th2, Th9, Th17, and the level of inflammatory factors included interferon-γ (IFN-γ), tumor necrosis factor-ɑ (TNF-ɑ), interleukin-17(IL-17) and interleukin-9 (IL-9) were compared in the two groups. Result: The expression levels of CD3+and CD8+ in the observation group were significantly lower than those in the control group, and the levels of CD4+ and CD4+/CD8+ were significantly higher than those in the control group. The expression levels of Th2, Th9 and Th17 in the observation group were significantly higher than those in the control group, while the expression levels of Th1 and Th1/Th2 were significantly lower than those in the control group. The expression levels of TNF-ɑ, IL-17 and IL-9 in the observation group were significantly higher than those in the control group, while the expression level of IFN-γ was significantly lower than that in the control group. Conclusion: The expression level of peripheral blood immunity and inflammatory factors in children with bronchial asthma plays an important role in the occurrence of bronchial asthma, and it is of great significance in clinical practice.