INTRODUCTION Microparticles （MPs） were increased in patients with coronary heart disease （CHD）,with the subtypes and quantity of MPs variate in different types of CHD.There were emerging reports indicating that MP...INTRODUCTION Microparticles （MPs） were increased in patients with coronary heart disease （CHD）,with the subtypes and quantity of MPs variate in different types of CHD.There were emerging reports indicating that MPs may play important roles in the pathogenesis of CHD.Here in this review we summarized the pro-inflammation,pro-coagulation effects of MPs,as well as their impacts on endothelial function and angiogenesis.MPs have the potential of being powerful diagnostic biomarkers and therapeutic tools in CHD patients in the future.展开更多
基金The study was supported by grants from the National Natural Science Foundation of China （No. 81300076） and the Beijing Natural Science Foundation （No. 7132195）.
文摘INTRODUCTION Microparticles （MPs） were increased in patients with coronary heart disease （CHD）,with the subtypes and quantity of MPs variate in different types of CHD.There were emerging reports indicating that MPs may play important roles in the pathogenesis of CHD.Here in this review we summarized the pro-inflammation,pro-coagulation effects of MPs,as well as their impacts on endothelial function and angiogenesis.MPs have the potential of being powerful diagnostic biomarkers and therapeutic tools in CHD patients in the future.
