Even though the severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)is related to SARS-CoV and Middle East respiratory syndrome coronavirus(MERS-CoV),identifying effective and safe therapeutic strategies remain...Even though the severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)is related to SARS-CoV and Middle East respiratory syndrome coronavirus(MERS-CoV),identifying effective and safe therapeutic strategies remains challenging.In search of finding effective treatments to eradicate the virus and improve disease symptoms,scientists are exploring possible therapies such as anti-viral,anti-malaria,immune therapy,and hormone treatments.However,the efficacy of these treatments was not validated on either SARS-CoV or MERS-CoV.In this study,we have reviewed synthetic evidence achieved through systematic and meta-analysis of therapeutics specific for SARS-CoV-2 and observed that the use of the above-mentioned therapies had no clinical benefits in coronavirus disease 2019 patients and,conversely,displayed side effects.展开更多
文摘Even though the severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)is related to SARS-CoV and Middle East respiratory syndrome coronavirus(MERS-CoV),identifying effective and safe therapeutic strategies remains challenging.In search of finding effective treatments to eradicate the virus and improve disease symptoms,scientists are exploring possible therapies such as anti-viral,anti-malaria,immune therapy,and hormone treatments.However,the efficacy of these treatments was not validated on either SARS-CoV or MERS-CoV.In this study,we have reviewed synthetic evidence achieved through systematic and meta-analysis of therapeutics specific for SARS-CoV-2 and observed that the use of the above-mentioned therapies had no clinical benefits in coronavirus disease 2019 patients and,conversely,displayed side effects.