Antenatal closure of the ductus arteriosus is an uncommon event that has been considered as a risk factor for development of congestive heart failure and pers istent pulmonary hypertension of the newborn. We report he...Antenatal closure of the ductus arteriosus is an uncommon event that has been considered as a risk factor for development of congestive heart failure and pers istent pulmonary hypertension of the newborn. We report here on a case of antena tal ductus arteriosus closure due to niflumic acid maternal intoxication at 32 weeks of gestation. Fetal extraction was performed few days later because of echo graphic signs of congestive heart failure. The child survived after 3 days of se vere persistent pulmonary hypertension. This case emphasizes the potential risk of niflumic acid during pregnancy and the need of antenatal echographic monitori ng for optimal management.展开更多
文摘Antenatal closure of the ductus arteriosus is an uncommon event that has been considered as a risk factor for development of congestive heart failure and pers istent pulmonary hypertension of the newborn. We report here on a case of antena tal ductus arteriosus closure due to niflumic acid maternal intoxication at 32 weeks of gestation. Fetal extraction was performed few days later because of echo graphic signs of congestive heart failure. The child survived after 3 days of se vere persistent pulmonary hypertension. This case emphasizes the potential risk of niflumic acid during pregnancy and the need of antenatal echographic monitori ng for optimal management.