Molten carbonate is an excellent electrolyte for the electrochemical reduction of CO_(2)to carbonaceous materials.However,the electrolyte–electrode-reaction relationship has not been well understood.Herein,we propose...Molten carbonate is an excellent electrolyte for the electrochemical reduction of CO_(2)to carbonaceous materials.However,the electrolyte–electrode-reaction relationship has not been well understood.Herein,we propose a general descriptor,the CO_(2)activity,to reveal the electrolyte–electrode-reaction relationship by thermodynamic calculations and experimental studies.Experimental studies agree well with theoretical predictions that both cations(Li^(+),Ca^(2+),Sr^(2+)and Ba^(2+))and anions(BO_(2)^(-),Ti_(5)O_(14)^(8-),SiO_(3)^(2-))can modulate the CO_(2)activity to control both cathode and anode reactions in a typical molten carbonate electrolyzer in terms of tuning reaction products and overpotentials.In this regard,the reduction of CO_(3)^(2-)can be interpreted as the direct reduction of CO_(2)generated from the dissociated CO_(3)^(2-),and the CO_(2)activity can be used as a general descriptor to predict the electrode reaction in molten carbonate.Overall,the CO_(2)activity descriptor unlocks the electrolyte–electrode-reaction relationship,thereby providing fundamental insights into guiding molten carbonate CO_(2)electrolysis.展开更多
Atmospheric carbon dioxide(CO_(2))concentration has reached record levels due to excessive anthropogenic CO_(2)emissions from massive industrial productions.Renewable-energy-driven CO_(2)electroreduction is an effecti...Atmospheric carbon dioxide(CO_(2))concentration has reached record levels due to excessive anthropogenic CO_(2)emissions from massive industrial productions.Renewable-energy-driven CO_(2)electroreduction is an effective method of directly converting CO_(2)into various value-added chemicals or materials without subsequent geological disposal treatment.Owing to their promising thermal stability,wide electrochemical window,tunable oxo-basicity,and nontoxic nature,molten salt electrolytes endow intrinsic advantages,such as fast CO_(2)absorption and selective electrochemical transformation,among different electrolyte species,wherein advanced carbon materials,CO,and hydrocarbons can be generated at relatively high current densities.Herein,we review the recent advances in molten salt CO_(2)capture and electrochemical transformation(MSCC-ET)technologies,including reaction mechanisms,CO_(2)absorption kinetics,electrode reaction kinetics,and product selectivity.This review highlights feasible strategies for regulating nanostructures,carbon product crystallinity,energy efficiency,overall CO_(2)conversion efficiency,and MSCC-ET adaptability toward practical flue gases.Moreover,suitable cost-effective inert anode candidates for the oxygen evolution reaction are discussed.展开更多
Spasticity is the main disabling clinical manifestation of children with cerebral palsy(CP).Selective dorsal rhizotomy(SDR)has been performed for the treatment of spastic CP in Asia for quite some time from 1990.The p...Spasticity is the main disabling clinical manifestation of children with cerebral palsy(CP).Selective dorsal rhizotomy(SDR)has been performed for the treatment of spastic CP in Asia for quite some time from 1990.The purpose of this review is to discuss the historical origin and development of SDR.Our goal here is to identify the current patient selection criteria for SDR and to point out indications and contraindications based on the patients with CP,age from 2 to 18 years-old,over 6000 cases,who received SDR surgery with spasticity of muscle tension more than 3 degrees in our center.We also discuss evidence-based approaches on how to evaluate postoperative patient outcomes of SDR and how complications can be avoided.Finally,we mention progress made in terms of SDR technical advances and how improvements can be made in the future.In conclusion,SDR surgery is a reliable way to improve outcomes of patients with spastic CP and can be done carefully in patients as long as stringent selection criteria are used.However,more research and technological advancements are needed to help address associated complications.展开更多
Spastic paralysis of the limb mainly results from the central lesion,in which spastic cerebral palsy is the common cause.Due to durative muscle spasm in spastic cerebral palsy,it is often accompanied by the formation ...Spastic paralysis of the limb mainly results from the central lesion,in which spastic cerebral palsy is the common cause.Due to durative muscle spasm in spastic cerebral palsy,it is often accompanied by the formation of secondary musculoskeletal deformities,resulting in limb motor disability.Based on its pathogenesis,surgical treatment is currently applied:selective posterior rhizotomy(SPR)or orthopedic surgery.The primary purpose of early orthopedic surgery was simply to correct limb deformities,which usually led to the recurrence of deformity as a result of the presence of spasticity.With the application of SPR,high muscle tone was successfully relieved,but limb deformity was still present postoperatively.Therefore,this study aimed to elaborate on the management of orthopedic surgery,common deformities of the lower limb,and orthopedic operative methods;discuss the relationship between SPR and orthopedic procedure for limb deformity;and focus on the indications,timing of intervention,and postoperative outcome of different surgical methods.展开更多
The choice of females to accept or reject male courtship is a critical decision for animal reproduction.Serotonin(5-hydroxytryptamine;5-HT)has been found to regulate sexual behavior in many species,but it is unclear h...The choice of females to accept or reject male courtship is a critical decision for animal reproduction.Serotonin(5-hydroxytryptamine;5-HT)has been found to regulate sexual behavior in many species,but it is unclear how 5-HT and its receptors function to regulate different aspects of sexual behavior.Here we used Drosophila melanogaster as the model animal to investigate how 5-HT and its receptors modulate female sexual receptivity.We found that knockout of tryptophan hydroxylase(Trh),which is involved in the biosynthesis of 5-HT,severely reduced virgin female receptivity without affecting post-mating behaviors.We identified a subset of sexually dimorphic Trh neurons that co-expressed fruitless(fru),in which the activity was correlated with sexual receptivity in females.We also found that 5-HT1A and 5-HT7 receptors regulate virgin female receptivity.Our findings demonstrate how 5-HT functions in sexually dimorphic neurons to promote virgin female receptivity through two of its receptors.展开更多
Dear Editor,Mosquitoes,as important arthropod disease vectors,efficiently transmit pathogens such as dengue virus,Zika virus,yellow fever virus,and malaria.To find their host,female mosquitoes use multiple sensory sys...Dear Editor,Mosquitoes,as important arthropod disease vectors,efficiently transmit pathogens such as dengue virus,Zika virus,yellow fever virus,and malaria.To find their host,female mosquitoes use multiple sensory systems to detect host-associated cues such as CO_(2),volatile odorants,visual signals,and temperature.展开更多
基金funded by National Natural Science Foun-dation of China(No.52031008,21673162).
文摘Molten carbonate is an excellent electrolyte for the electrochemical reduction of CO_(2)to carbonaceous materials.However,the electrolyte–electrode-reaction relationship has not been well understood.Herein,we propose a general descriptor,the CO_(2)activity,to reveal the electrolyte–electrode-reaction relationship by thermodynamic calculations and experimental studies.Experimental studies agree well with theoretical predictions that both cations(Li^(+),Ca^(2+),Sr^(2+)and Ba^(2+))and anions(BO_(2)^(-),Ti_(5)O_(14)^(8-),SiO_(3)^(2-))can modulate the CO_(2)activity to control both cathode and anode reactions in a typical molten carbonate electrolyzer in terms of tuning reaction products and overpotentials.In this regard,the reduction of CO_(3)^(2-)can be interpreted as the direct reduction of CO_(2)generated from the dissociated CO_(3)^(2-),and the CO_(2)activity can be used as a general descriptor to predict the electrode reaction in molten carbonate.Overall,the CO_(2)activity descriptor unlocks the electrolyte–electrode-reaction relationship,thereby providing fundamental insights into guiding molten carbonate CO_(2)electrolysis.
基金supported by the National Natural Science Foundation of China(52031008,22005225)the China Postdoctoral Science Foundation(2021T140523)the Fundamental Research Funds for the Central Universities(2042022kf1075)。
文摘Atmospheric carbon dioxide(CO_(2))concentration has reached record levels due to excessive anthropogenic CO_(2)emissions from massive industrial productions.Renewable-energy-driven CO_(2)electroreduction is an effective method of directly converting CO_(2)into various value-added chemicals or materials without subsequent geological disposal treatment.Owing to their promising thermal stability,wide electrochemical window,tunable oxo-basicity,and nontoxic nature,molten salt electrolytes endow intrinsic advantages,such as fast CO_(2)absorption and selective electrochemical transformation,among different electrolyte species,wherein advanced carbon materials,CO,and hydrocarbons can be generated at relatively high current densities.Herein,we review the recent advances in molten salt CO_(2)capture and electrochemical transformation(MSCC-ET)technologies,including reaction mechanisms,CO_(2)absorption kinetics,electrode reaction kinetics,and product selectivity.This review highlights feasible strategies for regulating nanostructures,carbon product crystallinity,energy efficiency,overall CO_(2)conversion efficiency,and MSCC-ET adaptability toward practical flue gases.Moreover,suitable cost-effective inert anode candidates for the oxygen evolution reaction are discussed.
基金the financial support from the National Natural Science Foundation of China (51602040 and 51872039)the Science and Technology Program of Sichuan (M112018JY0025)the Scientific Research Foundation for New Teachers of UESTC (A03013023601007)
文摘Spasticity is the main disabling clinical manifestation of children with cerebral palsy(CP).Selective dorsal rhizotomy(SDR)has been performed for the treatment of spastic CP in Asia for quite some time from 1990.The purpose of this review is to discuss the historical origin and development of SDR.Our goal here is to identify the current patient selection criteria for SDR and to point out indications and contraindications based on the patients with CP,age from 2 to 18 years-old,over 6000 cases,who received SDR surgery with spasticity of muscle tension more than 3 degrees in our center.We also discuss evidence-based approaches on how to evaluate postoperative patient outcomes of SDR and how complications can be avoided.Finally,we mention progress made in terms of SDR technical advances and how improvements can be made in the future.In conclusion,SDR surgery is a reliable way to improve outcomes of patients with spastic CP and can be done carefully in patients as long as stringent selection criteria are used.However,more research and technological advancements are needed to help address associated complications.
文摘Spastic paralysis of the limb mainly results from the central lesion,in which spastic cerebral palsy is the common cause.Due to durative muscle spasm in spastic cerebral palsy,it is often accompanied by the formation of secondary musculoskeletal deformities,resulting in limb motor disability.Based on its pathogenesis,surgical treatment is currently applied:selective posterior rhizotomy(SPR)or orthopedic surgery.The primary purpose of early orthopedic surgery was simply to correct limb deformities,which usually led to the recurrence of deformity as a result of the presence of spasticity.With the application of SPR,high muscle tone was successfully relieved,but limb deformity was still present postoperatively.Therefore,this study aimed to elaborate on the management of orthopedic surgery,common deformities of the lower limb,and orthopedic operative methods;discuss the relationship between SPR and orthopedic procedure for limb deformity;and focus on the indications,timing of intervention,and postoperative outcome of different surgical methods.
基金the National Natural Science Foundation of China(Y711181133 and Y711241133)the State Key Laboratory of Integrated Management of Pest Insects and Rodents at the Institute of Zoology of the Chinese Academy of Sciences(Y652751E03).
文摘The choice of females to accept or reject male courtship is a critical decision for animal reproduction.Serotonin(5-hydroxytryptamine;5-HT)has been found to regulate sexual behavior in many species,but it is unclear how 5-HT and its receptors function to regulate different aspects of sexual behavior.Here we used Drosophila melanogaster as the model animal to investigate how 5-HT and its receptors modulate female sexual receptivity.We found that knockout of tryptophan hydroxylase(Trh),which is involved in the biosynthesis of 5-HT,severely reduced virgin female receptivity without affecting post-mating behaviors.We identified a subset of sexually dimorphic Trh neurons that co-expressed fruitless(fru),in which the activity was correlated with sexual receptivity in females.We also found that 5-HT1A and 5-HT7 receptors regulate virgin female receptivity.Our findings demonstrate how 5-HT functions in sexually dimorphic neurons to promote virgin female receptivity through two of its receptors.
基金the National Natural Science Foundation of China(Y711181133)the State Key Laboratory of Integrated Management of Pest Insects and Rodents.Institute of Zoology,Chinese Academy of Sciences(Y952824103)。
文摘Dear Editor,Mosquitoes,as important arthropod disease vectors,efficiently transmit pathogens such as dengue virus,Zika virus,yellow fever virus,and malaria.To find their host,female mosquitoes use multiple sensory systems to detect host-associated cues such as CO_(2),volatile odorants,visual signals,and temperature.