Chromobacterium violaceum is a gram-negative bacterium of soil and water in tropical and subtropical environments. Typically,it is considered a bacterium of low virulence although,uncommonly, it causes human infection...Chromobacterium violaceum is a gram-negative bacterium of soil and water in tropical and subtropical environments. Typically,it is considered a bacterium of low virulence although,uncommonly, it causes human infection, particularly in persons with defects in host defenses. Infection generally follows exposure of broken skin to contaminated water and soil, and is often characterized by pustules, lymphadenitis, fever, and vomiting, as well as rapid dissemination and a high mortality rate. Unfortunately, because C violaceum is ubiquitous, it is often dismissed as a contaminant when cultured. Because rapid diagnosis (by taking appropriate specimens) and treatment are vital to a good prognosis, it is imperative that physicians be aware of this organism. In addition, patients with chromobacterial infections should have an immunologic workup because infections in immunocompetent individuals are rare. Here wereport an aggressive yet nonfatal case of Cviolaceum septicemia in an adolescent male, diagnosed through a punch biopsy of askin lesion, and resulting in a new diagnosis of chronic granulomatous disease.展开更多
文摘Chromobacterium violaceum is a gram-negative bacterium of soil and water in tropical and subtropical environments. Typically,it is considered a bacterium of low virulence although,uncommonly, it causes human infection, particularly in persons with defects in host defenses. Infection generally follows exposure of broken skin to contaminated water and soil, and is often characterized by pustules, lymphadenitis, fever, and vomiting, as well as rapid dissemination and a high mortality rate. Unfortunately, because C violaceum is ubiquitous, it is often dismissed as a contaminant when cultured. Because rapid diagnosis (by taking appropriate specimens) and treatment are vital to a good prognosis, it is imperative that physicians be aware of this organism. In addition, patients with chromobacterial infections should have an immunologic workup because infections in immunocompetent individuals are rare. Here wereport an aggressive yet nonfatal case of Cviolaceum septicemia in an adolescent male, diagnosed through a punch biopsy of askin lesion, and resulting in a new diagnosis of chronic granulomatous disease.
