Flexible energy storage devices have played a significant role in multiscenario applications,while flexible zinc-ion batteries(ZIBs),as an essential branch,have developed rapidly in recent years.Three-dimensional(3D)p...Flexible energy storage devices have played a significant role in multiscenario applications,while flexible zinc-ion batteries(ZIBs),as an essential branch,have developed rapidly in recent years.Three-dimensional(3D)printing is an extremely advanced technology to design and modify the structure of batteries and provides unlimited possibilities for the diversified development of energy storage equipment.Herein,by utilizing 3D printing technology,carbon nanotube(CNT)is coated by MnO_(2) to form a flexible CNT@MnO_(2) ink as a cathode for flexible aqueous micro-ZIBs for the first time and zinc powder ink is used as an anode due to its high flexibility and bendability.The Zn//CNT@MnO_(2) flexible battery shows a stable capacity of 63μAh cm^(−2) at 0.4mA cm^(−2).When the battery is bent in different states,the maximum capacity loss compared with the initial value is only 2.72%,indicating its stability.This study shows the potential of 3D printing technology in the development of flexible manganese-based ZIBs.展开更多
AIM To study the action of remedies of supporting resistance and relieving blood stasis on metastasis of postoperative gastric cancer and its influence on ornithine decarboxylase (ODC). METHODS Sixty three postope...AIM To study the action of remedies of supporting resistance and relieving blood stasis on metastasis of postoperative gastric cancer and its influence on ornithine decarboxylase (ODC). METHODS Sixty three postoperative gastric cancer patients were randomly divided into two groups. Thirty one patients were treated with western medicine consisting of the FAP scheme (5 flurouracil, adriamycin and cisplatin) and the CODP scheme (cyclophosphamide, vincristine, daunorubicin and prednisone), whereas 32 patients with the FAP scheme and traditional Chinese medicine. Correlations were approached between the ODC levels detected before and after treatment and some other factors including tumor diameter, infiltration depth, histological type and lymph node metastasis. RESULTS The ODC levels in the gastric cancers and normal gastric mucosa adjacent to the cancer tissues were significantly higher in the patients than those of the controls. The increasing ODC was obviously correlated with the tumor size, infiltration depth, differentiation type, and lymph node metastasis. Six months later there was no significant changes in the ODC levels of the group using only western medicine, while the ODC levels decreased markedly in the group using combined western and traditional Chinese medicine ( P <0 01). CONCLUSION The remedies of traditional Chinese medicine on the metastases of postoperative gastric cancers were related to the reduction of ODC activities.展开更多
INCE the unveiling of new evidence of biological experiments on humans conducted by the Japanese army in China in thefirst half of the last century, the brutality of Imperial Japan and its militarism have been univers...INCE the unveiling of new evidence of biological experiments on humans conducted by the Japanese army in China in thefirst half of the last century, the brutality of Imperial Japan and its militarism have been universally denounced.展开更多
目的研究双歧杆菌G9-1保护轮状病毒(RV)感染新生大鼠肠道通透性及肠道稳态的机制。方法将27只新生SD大鼠随机以1∶1∶1比例分为对照组(配方奶灌胃)、RV感染组(配方奶+0.6 ml RV培养液灌胃)和治疗组(配方奶+0.6 ml RV培养液灌胃,次日以...目的研究双歧杆菌G9-1保护轮状病毒(RV)感染新生大鼠肠道通透性及肠道稳态的机制。方法将27只新生SD大鼠随机以1∶1∶1比例分为对照组(配方奶灌胃)、RV感染组(配方奶+0.6 ml RV培养液灌胃)和治疗组(配方奶+0.6 ml RV培养液灌胃,次日以双歧杆菌G9-1溶液灌胃),苏木精伊红(HE)染色评估三组新生大鼠肠道组织病理变化,异硫氰酸荧光素-葡聚糖(FITC-Dextran)示踪法检测肠道通透性,酶联免疫吸附法检测血清D-乳酸(DLA)、二胺氧化酶(DAO)水平,实时荧光定量聚合酶链式反应(Real-time PCR)检测肠组织紧密连接相关蛋白-1(ZO-1)、紧密连接蛋白闭锁蛋白(Occludin)、闭合蛋白-1(Claudin-1)mRNA表达,蛋白免疫印迹电泳(Western blot)检测ZO-1、Occludin、Claudin-1蛋白表达,并分析其肠道菌群变化。结果治疗组新生大鼠肠组织病理学评分、FITC-Dextran含量、血清DLA、DAO水平低于RV感染组(P<0.05),治疗组肠组织紧密连接蛋白ZO-1、Occludin、Claudin-1 mRNA和蛋白表达高于RV感染组(P<0.05);治疗组双歧杆菌数量高于RV感染组(P<0.05),乳酸杆菌、大肠埃希菌数量与RV感染组比较,无统计学差异。结论双歧杆菌G9-1可有效降低RV感染新生大鼠肠道通透性,修复肠道屏障功能,改变肠道菌群结构,维持肠道稳态平衡。展开更多
Background Both repaglinide and gliclazide are insulin secretagogues widely used in the treatment of type 2 diabetes.They stimulate insulin secretion through distinct mechanisms and may benefit patients from different...Background Both repaglinide and gliclazide are insulin secretagogues widely used in the treatment of type 2 diabetes.They stimulate insulin secretion through distinct mechanisms and may benefit patients from different aspects.The present study was to evaluate the effects of repaglinide or gliclazide on glycaemic control,insulin secretion,and lipid profiles in type 2 diabetes patients.Methods A total of 47 newly diagnosed type 2 diabetes patients were randomized 1：1 to receive a 4-week treatment with repaglinide or gliclazide.The standard mixed meal tolerance test was performed before and after the treatment.Plasma glucose （PG）,insulin concentration,and lipid profiles were measured.The area under insulin concentration curve （AUCins） and the early-phase insulin secretion index （△I30/△G3o） were calculated.Results After the trial,fasting and postprandial PG and postprandial insulin improved significantly in both groups （P〈0.05）.The maximum insulin concentration occurred earlier in the repaglinide group than that in the gliclazide group.AUCins increased in both groups （P 〈0.05）,but no significant difference was found between groups.△I30/△G30 increased in both groups （P 〈0.05）,especially in the repaglinide group （P 〈0.05）.Triglyceride and total cholesterol decreased significantly in the repaglinide group in some time points,while no significant change was observed in the gliclazide group.Conclusions Repaglinide and gliclazide had similar effects on glycaemic control and total insulin secretion,while repaglinide had more effects on improvements in β-cell function and lipid metabolism.展开更多
In 2Q15, which marks the 70th anniversary of the end of the Chinese People＇s War of Resistance Against Japanese Aggression, Asian countries that suffered under Imperial Japan＇s expansionism will call for internation...In 2Q15, which marks the 70th anniversary of the end of the Chinese People＇s War of Resistance Against Japanese Aggression, Asian countries that suffered under Imperial Japan＇s expansionism will call for international justice with one voice, demanding Japan take a responsible stance by acknowledging its past militarism.展开更多
The gruesome crimes of Japanese Army＇s notorious Unit 731 should be a wakeup call for humanity By 8u Ping.With the emergence of new evidence of biological experiments on hu- mans conducted by the Japanesearmy in Chin...The gruesome crimes of Japanese Army＇s notorious Unit 731 should be a wakeup call for humanity By 8u Ping.With the emergence of new evidence of biological experiments on hu- mans conducted by the Japanesearmy in China in the first half of the last century, the brutal crimes of Imperial Japan and its militarism have been denounced universally.展开更多
基金supported by the National Natural Science Foundation of China(No.52071171)the Liaoning Revitalization Talents Program-Pan Deng Scholars(XLYC1802005)+6 种基金the Liaoning BaiQianWan Talents Program(LNBQW2018B0048)the Natural Science Fund of Liaoning Province for Excellent Young Scholars(2019-YQ-04)the Key Project of Scientific Research of the Education Department of Liaoning Province(LZD201902)the Foundation for Young Scholars of Liaoning University(a252102001)the Australian Research Council(ARC)Future Fellowship(FT210100298)the CSIRO Energy Centre and Kick-Start Projectthe Victorian Government's support through the provision of a grant from veski-Study Melbourne Research Partnerships(SMRP)project,Shenyang Science and Technology Project(21-108-9-04).
文摘Flexible energy storage devices have played a significant role in multiscenario applications,while flexible zinc-ion batteries(ZIBs),as an essential branch,have developed rapidly in recent years.Three-dimensional(3D)printing is an extremely advanced technology to design and modify the structure of batteries and provides unlimited possibilities for the diversified development of energy storage equipment.Herein,by utilizing 3D printing technology,carbon nanotube(CNT)is coated by MnO_(2) to form a flexible CNT@MnO_(2) ink as a cathode for flexible aqueous micro-ZIBs for the first time and zinc powder ink is used as an anode due to its high flexibility and bendability.The Zn//CNT@MnO_(2) flexible battery shows a stable capacity of 63μAh cm^(−2) at 0.4mA cm^(−2).When the battery is bent in different states,the maximum capacity loss compared with the initial value is only 2.72%,indicating its stability.This study shows the potential of 3D printing technology in the development of flexible manganese-based ZIBs.
文摘AIM To study the action of remedies of supporting resistance and relieving blood stasis on metastasis of postoperative gastric cancer and its influence on ornithine decarboxylase (ODC). METHODS Sixty three postoperative gastric cancer patients were randomly divided into two groups. Thirty one patients were treated with western medicine consisting of the FAP scheme (5 flurouracil, adriamycin and cisplatin) and the CODP scheme (cyclophosphamide, vincristine, daunorubicin and prednisone), whereas 32 patients with the FAP scheme and traditional Chinese medicine. Correlations were approached between the ODC levels detected before and after treatment and some other factors including tumor diameter, infiltration depth, histological type and lymph node metastasis. RESULTS The ODC levels in the gastric cancers and normal gastric mucosa adjacent to the cancer tissues were significantly higher in the patients than those of the controls. The increasing ODC was obviously correlated with the tumor size, infiltration depth, differentiation type, and lymph node metastasis. Six months later there was no significant changes in the ODC levels of the group using only western medicine, while the ODC levels decreased markedly in the group using combined western and traditional Chinese medicine ( P <0 01). CONCLUSION The remedies of traditional Chinese medicine on the metastases of postoperative gastric cancers were related to the reduction of ODC activities.
文摘INCE the unveiling of new evidence of biological experiments on humans conducted by the Japanese army in China in thefirst half of the last century, the brutality of Imperial Japan and its militarism have been universally denounced.
文摘目的研究双歧杆菌G9-1保护轮状病毒(RV)感染新生大鼠肠道通透性及肠道稳态的机制。方法将27只新生SD大鼠随机以1∶1∶1比例分为对照组(配方奶灌胃)、RV感染组(配方奶+0.6 ml RV培养液灌胃)和治疗组(配方奶+0.6 ml RV培养液灌胃,次日以双歧杆菌G9-1溶液灌胃),苏木精伊红(HE)染色评估三组新生大鼠肠道组织病理变化,异硫氰酸荧光素-葡聚糖(FITC-Dextran)示踪法检测肠道通透性,酶联免疫吸附法检测血清D-乳酸(DLA)、二胺氧化酶(DAO)水平,实时荧光定量聚合酶链式反应(Real-time PCR)检测肠组织紧密连接相关蛋白-1(ZO-1)、紧密连接蛋白闭锁蛋白(Occludin)、闭合蛋白-1(Claudin-1)mRNA表达,蛋白免疫印迹电泳(Western blot)检测ZO-1、Occludin、Claudin-1蛋白表达,并分析其肠道菌群变化。结果治疗组新生大鼠肠组织病理学评分、FITC-Dextran含量、血清DLA、DAO水平低于RV感染组(P<0.05),治疗组肠组织紧密连接蛋白ZO-1、Occludin、Claudin-1 mRNA和蛋白表达高于RV感染组(P<0.05);治疗组双歧杆菌数量高于RV感染组(P<0.05),乳酸杆菌、大肠埃希菌数量与RV感染组比较,无统计学差异。结论双歧杆菌G9-1可有效降低RV感染新生大鼠肠道通透性,修复肠道屏障功能,改变肠道菌群结构,维持肠道稳态平衡。
文摘Background Both repaglinide and gliclazide are insulin secretagogues widely used in the treatment of type 2 diabetes.They stimulate insulin secretion through distinct mechanisms and may benefit patients from different aspects.The present study was to evaluate the effects of repaglinide or gliclazide on glycaemic control,insulin secretion,and lipid profiles in type 2 diabetes patients.Methods A total of 47 newly diagnosed type 2 diabetes patients were randomized 1：1 to receive a 4-week treatment with repaglinide or gliclazide.The standard mixed meal tolerance test was performed before and after the treatment.Plasma glucose （PG）,insulin concentration,and lipid profiles were measured.The area under insulin concentration curve （AUCins） and the early-phase insulin secretion index （△I30/△G3o） were calculated.Results After the trial,fasting and postprandial PG and postprandial insulin improved significantly in both groups （P〈0.05）.The maximum insulin concentration occurred earlier in the repaglinide group than that in the gliclazide group.AUCins increased in both groups （P 〈0.05）,but no significant difference was found between groups.△I30/△G30 increased in both groups （P 〈0.05）,especially in the repaglinide group （P 〈0.05）.Triglyceride and total cholesterol decreased significantly in the repaglinide group in some time points,while no significant change was observed in the gliclazide group.Conclusions Repaglinide and gliclazide had similar effects on glycaemic control and total insulin secretion,while repaglinide had more effects on improvements in β-cell function and lipid metabolism.
文摘In 2Q15, which marks the 70th anniversary of the end of the Chinese People＇s War of Resistance Against Japanese Aggression, Asian countries that suffered under Imperial Japan＇s expansionism will call for international justice with one voice, demanding Japan take a responsible stance by acknowledging its past militarism.
文摘The gruesome crimes of Japanese Army＇s notorious Unit 731 should be a wakeup call for humanity By 8u Ping.With the emergence of new evidence of biological experiments on hu- mans conducted by the Japanesearmy in China in the first half of the last century, the brutal crimes of Imperial Japan and its militarism have been denounced universally.
