老年病人血清Aβ42与磷酸化Tau蛋白检测的临床价值

目的旨在探讨血清Aβ42与磷酸化Tau蛋白(p-Tau)检测的临床价值。方法收集南京大学医学院附属鼓楼医院已开展的425例门诊或住院60岁以上老年病人的血清Aβ42与p-Tau检测结果(两项均为同时检测),分析其在痴呆或其他疾病病人中的阳性率情况。结果血清Aβ42与p-Tau的总体阳性率分别为36.2%与24.7%,同时阳性率为21.4%。血清Aβ42在诊断为认知功能障碍、痴呆及AD的病人中的阳性率分别为23.8%、44.9%与50.0%,血清p-Tau分别为12.4%、22.4%与16.7%。然而,它们在具有肺部炎症或感染的病人中阳性率高达64.7%,并且两者几乎同时为阳性。结论血清Aβ42与p-Tau水平对AD的辅助诊断价值可能有限,但对提示肺部感染可能具有临床价值。

Correlation between Cr^(6+) and Mn^(2+) Adsorption in Rock-soil Medium with Combined Pollution

[Objective] The aim was to study the correlation between Cr6+ and Mn2+ adsorption in rock-soil medium with combined pollution. [Method] Combining single Cr6+ and Mn2+ adsorption test with combined pollution test, the adsorption laws of Cr6+ and Mn2+ were studied, and the correlation between Cr6+ and Mn2+ adsorption was analysed by using correlation analysis and regression analysis. [Result] According to the comparative analysis on adsorption tests, the adsorption time, adsorption amount and adsorption speed of Cr6+ and Mn2+ were obviously distinct in single adsorption test and combined adsorption test. Correlation analysis revealed that there was a significantly positive correlation between Cr6+ and Mn2+, and there existed addition effects between Cr6+ and Mn2+ in regression analysis, that is, the adsorption of Cr6+ by the soil tested would be enhanced by Mn2+. [Conclusion] The research could provide scientific references for environmental control and environmental management.