目的评价孕激素在先兆流产患者中的治疗效果,并探索不同制剂、用药途径是否存在差异。方法检索数据库MEDLINE、EMBASE、Cochrane Database of Clinical Trials、ClinicalTrials.gov,检索时间为建库至2020年5月,比较了先兆流产患者中孕...目的评价孕激素在先兆流产患者中的治疗效果,并探索不同制剂、用药途径是否存在差异。方法检索数据库MEDLINE、EMBASE、Cochrane Database of Clinical Trials、ClinicalTrials.gov,检索时间为建库至2020年5月,比较了先兆流产患者中孕激素组与对照组(安慰剂或未治疗组)妊娠结局指标的所有随机对照试验(RCT)。两位研究者独立进行数据提取及分析,应用RevMan5.3软件对孕激素组和对照组患者的妊娠结局进行Meta分析。结果共检索到85篇文章,其中符合纳入标准的有11篇,共计5076例先兆流产患者被纳入Meta分析。(1)与对照组相比,孕激素组先兆流产患者的流产率显著降低(P<0.05)。不同孕激素制剂亚组分析显示,地屈孕酮和黄体酮均显著降低了先兆流产患者的流产率(P<0.05);不同给药途径亚组分析显示,口服孕激素在降低流产率方面显著优于对照组(P<0.05),而经阴道应用孕激素与对照组无统计学差异(P>0.05)。不同地区和不同研究规模的亚组分析显示,孕激素组与对照组相比,先兆流产患者的流产率均显著降低(P<0.05)。(2)与对照组相比,孕激素组的活产率显著提高(P<0.05)。不同孕激素制剂亚组分析显示,与对照组相比,地屈孕酮亚组的活产率显著提高(P<0.05),而黄体酮亚组无统计学差异(P>0.05);不同给药途径亚组分析显示,与对照组相比,口服孕激素显著提高活产率(P<0.05),而经阴道应用孕激素与对照组无统计学差异(P>0.05)。(3)孕激素组与对照组在新生儿先天性异常及低体重的发生率方面均无统计学差异(P>0.05)。结论孕激素可以降低先兆流产患者的流产率,提高活产率,且未增加新生儿相关不良结局的发生;但不同孕激素制剂和给药途径的治疗效果存在差异。口服地屈孕酮治疗可降低先兆流产患者的流产率并提高活产率,值得临床推荐应用。展开更多
In this paper,analyzing the experiment data of multiple scanning probes in the arc wind-driven hypersonic plasma flows with the chaos dynamics method,we have obtained the power spectrum,the frequency wavenumber spectr...In this paper,analyzing the experiment data of multiple scanning probes in the arc wind-driven hypersonic plasma flows with the chaos dynamics method,we have obtained the power spectrum,the frequency wavenumber spectral density,the correlation dimension and Kolmogorov entropy of the flows,respectively.The distribution of correlation dimension and Kolmogorov entropy of the blunt cone wakes along the axis and the radius of the flows are presented successfully in the flows.The distributions clearly show the structure of turbulence and lamination in blunt cone wakes.Using the method of minimum Kolmogorov entropy,we observed the structure of the bow shock at far wake region in the blunt cone wakes.展开更多
In this paper,a controlled laboratory experiment to investigate the response properties of reflec-tometry to the density fluctuations is presented.The reflectometer signal is observed to be highly spatially localized ...In this paper,a controlled laboratory experiment to investigate the response properties of reflec-tometry to the density fluctuations is presented.The reflectometer signal is observed to be highly spatially localized in the plasma.The quantitative measurement has demonstrated that the signal originates about one free space wavelength of the probe•wave in front of the critical layer and this position is independent of the fluctuation wavenumber.It is also found that the sensitivity of transverse response to wavenumbers is different from that of longitudinal response.展开更多
The reflection of X-band microwaves (8-12 GHz) from a metallic aluminum (A1) surface with groove grating corrugations was investigated experimentally. It was shown that the reflection of p-polarization is much les...The reflection of X-band microwaves (8-12 GHz) from a metallic aluminum (A1) surface with groove grating corrugations was investigated experimentally. It was shown that the reflection of p-polarization is much less than the microwave reflected from the corresponding area of an unruled Al surface, with selective wavelength. The experimental results demonstrated that the anomalous microwave reflection is strongly associated with the excitation of spoof surface plasmons at the Al air interface by the surface grating coupler. This near-total absence of reflected microwaves is similar to the famous Wood's anomaly in the optical regime and is of fundamental importance to the applications of spoof surface plasmons in the microwave regime.展开更多
文摘目的评价孕激素在先兆流产患者中的治疗效果,并探索不同制剂、用药途径是否存在差异。方法检索数据库MEDLINE、EMBASE、Cochrane Database of Clinical Trials、ClinicalTrials.gov,检索时间为建库至2020年5月,比较了先兆流产患者中孕激素组与对照组(安慰剂或未治疗组)妊娠结局指标的所有随机对照试验(RCT)。两位研究者独立进行数据提取及分析,应用RevMan5.3软件对孕激素组和对照组患者的妊娠结局进行Meta分析。结果共检索到85篇文章,其中符合纳入标准的有11篇,共计5076例先兆流产患者被纳入Meta分析。(1)与对照组相比,孕激素组先兆流产患者的流产率显著降低(P<0.05)。不同孕激素制剂亚组分析显示,地屈孕酮和黄体酮均显著降低了先兆流产患者的流产率(P<0.05);不同给药途径亚组分析显示,口服孕激素在降低流产率方面显著优于对照组(P<0.05),而经阴道应用孕激素与对照组无统计学差异(P>0.05)。不同地区和不同研究规模的亚组分析显示,孕激素组与对照组相比,先兆流产患者的流产率均显著降低(P<0.05)。(2)与对照组相比,孕激素组的活产率显著提高(P<0.05)。不同孕激素制剂亚组分析显示,与对照组相比,地屈孕酮亚组的活产率显著提高(P<0.05),而黄体酮亚组无统计学差异(P>0.05);不同给药途径亚组分析显示,与对照组相比,口服孕激素显著提高活产率(P<0.05),而经阴道应用孕激素与对照组无统计学差异(P>0.05)。(3)孕激素组与对照组在新生儿先天性异常及低体重的发生率方面均无统计学差异(P>0.05)。结论孕激素可以降低先兆流产患者的流产率,提高活产率,且未增加新生儿相关不良结局的发生;但不同孕激素制剂和给药途径的治疗效果存在差异。口服地屈孕酮治疗可降低先兆流产患者的流产率并提高活产率,值得临床推荐应用。
文摘In this paper,analyzing the experiment data of multiple scanning probes in the arc wind-driven hypersonic plasma flows with the chaos dynamics method,we have obtained the power spectrum,the frequency wavenumber spectral density,the correlation dimension and Kolmogorov entropy of the flows,respectively.The distribution of correlation dimension and Kolmogorov entropy of the blunt cone wakes along the axis and the radius of the flows are presented successfully in the flows.The distributions clearly show the structure of turbulence and lamination in blunt cone wakes.Using the method of minimum Kolmogorov entropy,we observed the structure of the bow shock at far wake region in the blunt cone wakes.
基金Supported by the National Natural Science Foundation of Chinathe Doctoral Training Foundation of National Education Commission and Chinese Academy of Sciences.
文摘In this paper,a controlled laboratory experiment to investigate the response properties of reflec-tometry to the density fluctuations is presented.The reflectometer signal is observed to be highly spatially localized in the plasma.The quantitative measurement has demonstrated that the signal originates about one free space wavelength of the probe•wave in front of the critical layer and this position is independent of the fluctuation wavenumber.It is also found that the sensitivity of transverse response to wavenumbers is different from that of longitudinal response.
基金Project supported by the National Basic Research Program of China(Grant No.2008CB717800)the Doctoral Program o fMinistry of Education of China(Grant No.20093402110027)
文摘The reflection of X-band microwaves (8-12 GHz) from a metallic aluminum (A1) surface with groove grating corrugations was investigated experimentally. It was shown that the reflection of p-polarization is much less than the microwave reflected from the corresponding area of an unruled Al surface, with selective wavelength. The experimental results demonstrated that the anomalous microwave reflection is strongly associated with the excitation of spoof surface plasmons at the Al air interface by the surface grating coupler. This near-total absence of reflected microwaves is similar to the famous Wood's anomaly in the optical regime and is of fundamental importance to the applications of spoof surface plasmons in the microwave regime.