Objective To Explore the mechanism of the acupuncture on posanenopausal osteoporo-sis.Method One hundred Wistar female rats(6 month- old)were randomly divided into two groups: O-variectomized group and sham - opera...Objective To Explore the mechanism of the acupuncture on posanenopausal osteoporo-sis.Method One hundred Wistar female rats(6 month- old)were randomly divided into two groups: O-variectomized group and sham - operated group. After 3 months of operation, three rats were chosen tomeasure the bone histomorphometric indexes. Then the ovariectomized rats were distributed randomly to acupuncture group and yigaining group and normal saline group and control 2 group, the rats were respec-tively treated by acupuncture and yigaining and normal saline. After the treatment for three course, all rats were collected blood from the ateria femoralis, the levels of calcitonin were measured by IRMA. the bone histomorphometric indexes and C - cell in thyroid follicle were detected. Results The levels of calcitonin of acupuncture group were increasing significantly comparing with the yigaining group and the normal saline group and the control 2 group ( p < 0.05), but there were no evident difference in the levels of cal-citonin between the acupuncture group and the sham - operated group. The mean trabecular bone width and the tmbecuhar bone volume % of acupuncture group were increasing more than that of the normal saline group and the control 2 group(p < 0.05) ;the mean marrow cavity width and the marrow cavity vol-ume % were derreasing more than that of the nomal saline group and the control 2 group( P < 0.05) ; the number of C - cell in thyroid follicle of the acupuncture group were increasing more than that of the other groups except the sham - operated group. Conclusion Acupuncture can effectively treat the post-menopausal osteoporosis by strengthening the ability of the C - cell in thyroid follicle which can improve the levels of calcitonin in serum.展开更多
文摘Objective To Explore the mechanism of the acupuncture on posanenopausal osteoporo-sis.Method One hundred Wistar female rats(6 month- old)were randomly divided into two groups: O-variectomized group and sham - operated group. After 3 months of operation, three rats were chosen tomeasure the bone histomorphometric indexes. Then the ovariectomized rats were distributed randomly to acupuncture group and yigaining group and normal saline group and control 2 group, the rats were respec-tively treated by acupuncture and yigaining and normal saline. After the treatment for three course, all rats were collected blood from the ateria femoralis, the levels of calcitonin were measured by IRMA. the bone histomorphometric indexes and C - cell in thyroid follicle were detected. Results The levels of calcitonin of acupuncture group were increasing significantly comparing with the yigaining group and the normal saline group and the control 2 group ( p < 0.05), but there were no evident difference in the levels of cal-citonin between the acupuncture group and the sham - operated group. The mean trabecular bone width and the tmbecuhar bone volume % of acupuncture group were increasing more than that of the normal saline group and the control 2 group(p < 0.05) ;the mean marrow cavity width and the marrow cavity vol-ume % were derreasing more than that of the nomal saline group and the control 2 group( P < 0.05) ; the number of C - cell in thyroid follicle of the acupuncture group were increasing more than that of the other groups except the sham - operated group. Conclusion Acupuncture can effectively treat the post-menopausal osteoporosis by strengthening the ability of the C - cell in thyroid follicle which can improve the levels of calcitonin in serum.
