提出了矢量水听器低频绝对校准装置。首先给出了矢量水听器绝对校准的原理,通过测量声源辐射面的加速度,利用驻波管中平面驻波声场中的声压、质点振速和质点加速度在垂直方向上的分布规律,得出了校准计算公式;之后对校准装置中平面驻波...提出了矢量水听器低频绝对校准装置。首先给出了矢量水听器绝对校准的原理,通过测量声源辐射面的加速度,利用驻波管中平面驻波声场中的声压、质点振速和质点加速度在垂直方向上的分布规律,得出了校准计算公式;之后对校准装置中平面驻波场在垂直方向上的分布规律进行了测量验证,并对测量用加速度计进行了校准;最后对待校矢量水听器的灵敏度和指向性进行了测试。结果表明:在10~315 Hz频带内,矢量水听器低频绝对校准装置在±1 d B误差允许范围内,可用于矢量水听器的绝对校准。展开更多
Idiopathic pulmonary arterial hypertension(IPAH) is a rare disease of unknown etiology.The exact pathogenesis of pulmonary arterial hypertension is still not well known.In the past decades,many protein molecules have ...Idiopathic pulmonary arterial hypertension(IPAH) is a rare disease of unknown etiology.The exact pathogenesis of pulmonary arterial hypertension is still not well known.In the past decades,many protein molecules have been found to be in-volved in the development of IPAH.With proteomic techniques,profiling of human plasma proteome becomes more feasible in searching for disease-related markers.In present study,we showed the protein expression profiles of the serum of IPAH and healthy controls after depleting a few high-abundant proteins in serum.Thirteen spots had changed significantly in IPAH com-pared with healthy controls and were identified by LC-MS/MS.Alpha-1-antitrypsin and vitronectin were down-regulated in IPAH and may be valuable candidates for further explorations of their roles in the development of IPAH.展开更多
文摘提出了矢量水听器低频绝对校准装置。首先给出了矢量水听器绝对校准的原理,通过测量声源辐射面的加速度,利用驻波管中平面驻波声场中的声压、质点振速和质点加速度在垂直方向上的分布规律,得出了校准计算公式;之后对校准装置中平面驻波场在垂直方向上的分布规律进行了测量验证,并对测量用加速度计进行了校准;最后对待校矢量水听器的灵敏度和指向性进行了测试。结果表明:在10~315 Hz频带内,矢量水听器低频绝对校准装置在±1 d B误差允许范围内,可用于矢量水听器的绝对校准。
基金Project (No. A-007) supported by the Key Medicine Foundation of Zhejiang Province, China
文摘Idiopathic pulmonary arterial hypertension(IPAH) is a rare disease of unknown etiology.The exact pathogenesis of pulmonary arterial hypertension is still not well known.In the past decades,many protein molecules have been found to be in-volved in the development of IPAH.With proteomic techniques,profiling of human plasma proteome becomes more feasible in searching for disease-related markers.In present study,we showed the protein expression profiles of the serum of IPAH and healthy controls after depleting a few high-abundant proteins in serum.Thirteen spots had changed significantly in IPAH com-pared with healthy controls and were identified by LC-MS/MS.Alpha-1-antitrypsin and vitronectin were down-regulated in IPAH and may be valuable candidates for further explorations of their roles in the development of IPAH.