AIM To recognize the characteristic findings of micrQliver cancer (MLC) and to evaluate the effect of CT arterial portography (CTAP) and CT hepatic arteriography (CTHA) in diagnosis of MLC. METHODS Between April 1996 ...AIM To recognize the characteristic findings of micrQliver cancer (MLC) and to evaluate the effect of CT arterial portography (CTAP) and CT hepatic arteriography (CTHA) in diagnosis of MLC. METHODS Between April 1996 to December 1998, CTAP and CTHA were performed in 12patients with MLC, which were not detect ed byconventional CT examinations. After CTHA, 3 mL-- 5 mL mixture of lipiodol, doxorubic in andmitomycin C were injected into hepatic arterythrough the catheter, and then followed up by CTthree or four weeks later (Lipiodol CT LP-CT).RESULTS A total of 22 micro--tumors (0 .2 cm 0.6 cm in diameter ) were detected in 12patients, which manifested as small perfusiondefects in CTAP and small round enhancement inCTHA. The rate of detectability of CTAP andCTHA was 68.2% (15/ 22) and 77.3% (17/ 22)respectively, and the rate of the simultaneoususe of both procedures reached 86. 4% (19/ 22 ).All micro--tumors were demonstrated as punctatelipiodol deposit fool in LP--CT. After LP--CT, theelevated serum level of Q-fetoprotein (AFP)dropped to the normal level in all patients.CONCLUSION The CTAP and CTHA are the mostsensitive imaging methods for detecting microIiver cancer. Confirmed by the change of theelevated serum AFP level and lipiodol depositfool in LP-CT, small perfusion defects in CTAPand punctate enhancement in CTHA may suggestmicro--liver cancer.展开更多
基于机器学习(Machine Learning,ML)的天气预报模型近些年取得了显著进展,展示了优越的预报性能.与欧洲中期天气预报中心(European Centre for Medium-Range Weather Forecasts,ECMWF)的高分辨率预报(High-Resolution Forecasts,HRES)相...基于机器学习(Machine Learning,ML)的天气预报模型近些年取得了显著进展,展示了优越的预报性能.与欧洲中期天气预报中心(European Centre for Medium-Range Weather Forecasts,ECMWF)的高分辨率预报(High-Resolution Forecasts,HRES)相比,FuXi等先进的基于ML的天气预报模型,在统计预报指标上表现出色.然而,这些模型存在着共同的局限性,即随着预报时间步长的增加,预报结果趋于平滑,导致极端天气事件强度的低估.为了解决这一问题,本文研发了FuXi-Extreme模型.该模型采用去噪扩散概率模型(Denoising Diffusion Probabilistic Model,DDPM),增强了FuXi模型在5天预报中的地表预报数据细节.对极端总降水量(Total Precipitation,TP)、10m风速(10-meter Wind Speed,WS10)和2m温度(2-meter Temperature,T2M)的评估表明,FuXi-Extreme在性能上优于FuXi和HRES.此外,基于国际热带气旋最佳路径资料集(International Best Track Archive for Climate Stewardship,IBTrACS)的评估显示,与HRES相比,FuXi和FuXi-Extreme在热带气旋(Tropical Cyclone,TC)路径预报方面表现优异,但在TC强度预报方面仍有不足.展开更多
基金Supported by“9.5”National Major Project of National Cammittee of Sciences and Technology,No.96-907-03-02.
文摘AIM To recognize the characteristic findings of micrQliver cancer (MLC) and to evaluate the effect of CT arterial portography (CTAP) and CT hepatic arteriography (CTHA) in diagnosis of MLC. METHODS Between April 1996 to December 1998, CTAP and CTHA were performed in 12patients with MLC, which were not detect ed byconventional CT examinations. After CTHA, 3 mL-- 5 mL mixture of lipiodol, doxorubic in andmitomycin C were injected into hepatic arterythrough the catheter, and then followed up by CTthree or four weeks later (Lipiodol CT LP-CT).RESULTS A total of 22 micro--tumors (0 .2 cm 0.6 cm in diameter ) were detected in 12patients, which manifested as small perfusiondefects in CTAP and small round enhancement inCTHA. The rate of detectability of CTAP andCTHA was 68.2% (15/ 22) and 77.3% (17/ 22)respectively, and the rate of the simultaneoususe of both procedures reached 86. 4% (19/ 22 ).All micro--tumors were demonstrated as punctatelipiodol deposit fool in LP--CT. After LP--CT, theelevated serum level of Q-fetoprotein (AFP)dropped to the normal level in all patients.CONCLUSION The CTAP and CTHA are the mostsensitive imaging methods for detecting microIiver cancer. Confirmed by the change of theelevated serum AFP level and lipiodol depositfool in LP-CT, small perfusion defects in CTAPand punctate enhancement in CTHA may suggestmicro--liver cancer.
