Based on the analysis of the formation process of regional innovation capacity, this paper expatiates that the technology is the basis for industrial structure upgrading, while technological innovation is the power of...Based on the analysis of the formation process of regional innovation capacity, this paper expatiates that the technology is the basis for industrial structure upgrading, while technological innovation is the power of regional innovation capacity. It points out that the essential of regional industrial structure upgrading is the transition of regional technology structure from one balance to another. The mechanism of realizing industrial structure upgrading through technology-driven regional innovation capacity is also discussed briefly.展开更多
Acute myocardial ischaemia is a common acute .disease and a common cause of sudden death.However, it is difficult to diagnose in patients who died within 6 hours after the onset of myocardial ischaemia. The occurrence...Acute myocardial ischaemia is a common acute .disease and a common cause of sudden death.However, it is difficult to diagnose in patients who died within 6 hours after the onset of myocardial ischaemia. The occurrence of sudden cardiac death often has pathological basis of primary heart diseases, which may lead to a series of changes in metabolism and gene expression.1 Recent research found that hypoxia inducible factor 1 alpha （HIF-1α） is a sensitive marker of hypoxia; its gene expression is upregulated within several minutes after acute myocardial ischaemia, followed by the upregulation of its protein and its expression will remain high if the inducement continues. Its expression in nonhypoxic cardiac muscle is very low. This characteristic may be used to differentiate hypoxic factors from nonhypoxic factors, and help to judge the cause of death. This study explored the expression of HIF-1α in hypoxic cardiac muscle by establishing an acute myocardial ischaemia model in mice, and observed its dynamic changes to provide reference for analysing causes of death within 48 hours after death.展开更多
文摘Based on the analysis of the formation process of regional innovation capacity, this paper expatiates that the technology is the basis for industrial structure upgrading, while technological innovation is the power of regional innovation capacity. It points out that the essential of regional industrial structure upgrading is the transition of regional technology structure from one balance to another. The mechanism of realizing industrial structure upgrading through technology-driven regional innovation capacity is also discussed briefly.
基金National Natural Science Foundation of China(No.30500610)
文摘Acute myocardial ischaemia is a common acute .disease and a common cause of sudden death.However, it is difficult to diagnose in patients who died within 6 hours after the onset of myocardial ischaemia. The occurrence of sudden cardiac death often has pathological basis of primary heart diseases, which may lead to a series of changes in metabolism and gene expression.1 Recent research found that hypoxia inducible factor 1 alpha （HIF-1α） is a sensitive marker of hypoxia; its gene expression is upregulated within several minutes after acute myocardial ischaemia, followed by the upregulation of its protein and its expression will remain high if the inducement continues. Its expression in nonhypoxic cardiac muscle is very low. This characteristic may be used to differentiate hypoxic factors from nonhypoxic factors, and help to judge the cause of death. This study explored the expression of HIF-1α in hypoxic cardiac muscle by establishing an acute myocardial ischaemia model in mice, and observed its dynamic changes to provide reference for analysing causes of death within 48 hours after death.
