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太芪培元颗粒联合HAART对HIV/AIDS患者免疫重建的影响 被引量:4
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作者 刘旭辉 陈媛媛 +3 位作者 侯明杰 王延 原海 赵清霞 《亚太传统医药》 2020年第5期108-111,共4页
目的:观察太芪培元颗粒联合高效抗反转录病毒治疗(HAART)对艾滋病病毒(HIV)感染者/艾滋病(AIDS)患者免疫重建的影响。方法:选取88例HIV/AIDS患者随机分为对照组和观察组,每组44例;对照组给予HAART治疗,观察组给予太芪培元颗粒联合HAART... 目的:观察太芪培元颗粒联合高效抗反转录病毒治疗(HAART)对艾滋病病毒(HIV)感染者/艾滋病(AIDS)患者免疫重建的影响。方法:选取88例HIV/AIDS患者随机分为对照组和观察组,每组44例;对照组给予HAART治疗,观察组给予太芪培元颗粒联合HAART治疗,疗程均为12个月;比较两组免疫重建成功率及治疗前后CD4^+、CD8^+T淋巴细胞计数、症状与体征评分、卡氏评分变化。结果:剔除试验过程中5例失访者、1例自行退出者,最终统计完成82例,其中对照组40例,观察组42例。免疫重建成功率:观察组为80.95%,明显高于对照组的60.00%(P<0.05)。治疗后,观察组CD4^+、CD4^+CD45RA^+、CD8^+T淋巴细胞计数绝对值均明显高于对照组(P<0.05)。治疗后,观察组症状与体征评分明显低于对照组,卡氏评分明显高于对照组,差异均有统计学意义(P<0.05)。结论:太芪培元颗粒联合HAART治疗能够增强HIV/AIDS患者免疫重建疗效,改善临床症状,提高生活质量。 展开更多
关键词 艾滋病 高效抗反转录病毒治疗 太芪培元颗粒 免疫重建
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Key Social Determinants to Narrow the Gap between Health-adjusted Life Expectancy and Life Expectancy in Megacities
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作者 XI Jun Yan chen yuan yuan +7 位作者 ZHANG Yu Qin LUO Ao DU Zhi cheng LIANG Bo Heng DONG Hang LIN Xiao QIN Peng Zhe HAO yuan Tao 《Biomedical and Environmental Sciences》 SCIE CAS CSCD 2022年第9期773-781,共9页
Objective Improvement in the quality of life is reflected in the narrowing of the gap between healthadjusted life expectancy(HALE)and life expectancy(LE).The effect of megacity expansion on narrowing the gap is rarely... Objective Improvement in the quality of life is reflected in the narrowing of the gap between healthadjusted life expectancy(HALE)and life expectancy(LE).The effect of megacity expansion on narrowing the gap is rarely reported.This study aimed to disclose this potential relationship.Methods Annual life tables were constructed from identified death records and population counts from multiple administrative sources in Guangzhou,China,from 2010 to 2020.Joinpoint regression was used to evaluate the temporal trend.Generalized principal component analysis and multilevel models were applied to examine the county-level association between the gap and social determinants.Results Although LE and HALE in megacities are increasing steadily,their gap is widening.Socioeconomic and health services are guaranteed to narrow this gap.Increasing personal wealth,a growing number of newborns and healthy immigrants,high urbanization,and healthy aging have helped in narrowing this gap.Conclusion In megacities,parallel LE and HALE growth should be highly considered to narrow their gap.Multiple social determinants need to be integrated as a whole to formulate public health plans. 展开更多
关键词 Generalized principal component analysis Health-adjusted life expectancy MEGACITIES Quality of life Social determinants Temporal trend Urban expansion
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CNT@leather-based electronic bidirectional pressure sensor 被引量:1
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作者 chen yuan yuan XIE RuiJie +7 位作者 ZOU BingHua LIU YiHan ZHANG Kang LI Sheng ZHENG Bing ZHANG WeiNa WU JianSheng HUO Feng 《Science China(Technological Sciences)》 SCIE EI CAS CSCD 2020年第10期2137-2146,共10页
The ability of perceiving external pressures and conducting corresponding signals is one of the important functions of flexible electronics,which has been widely studied in electronic skin,prosthetics,robotics,healthc... The ability of perceiving external pressures and conducting corresponding signals is one of the important functions of flexible electronics,which has been widely studied in electronic skin,prosthetics,robotics,healthcare,human-machine interfaces,etc.Pressure sensor should not be limited to the detection of unidirectional pressure.Here,a leather-based electronic pressure sensor and corresponding arrays with bidirectional sensing capability are demonstrated.The sensor/arrays consisting of two pieces of stacked leather both modified with acidified carbon nanotubes(a-CNTs)can achieve multi-level response to pressure over a broad working range and sense pulling force opposite to pressure.With polyurethane mixed with ferriferrous oxide(Fe3O4)powder being applied to their upper surface,the resistive sensor/individual units of arrays can also detect the magnetic field because of the contactless pulling force generated by the magnetized Fe3O4.Being able to sense pressure,pulling force and magnetic field,the leather-based electronic bidirectional pressure sensor and corresponding arrays with good performance not only exhibit potential for mass production and their broad application prospects,but also provide a new insight for the development of flexible electronics. 展开更多
关键词 flexible electronics LEATHER bidirectional detection pressing/pulling force magnetic field sensing
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Synchronizability of time-varying structured duplex dynamical networks with different intra-layer rewiring mechanisms
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作者 WU XiaoQun ZHOU Xiong +2 位作者 LIU Jie YANG QiRui chen yuan yuan 《Science China(Technological Sciences)》 SCIE EI CAS CSCD 2022年第2期375-385,共11页
Global synchronizability of duplex networks induced by three different intra-layer rewiring mechanisms is explored in this paper.The rewiring mechanisms are named as model-preserving rewiring(MPR), simply direct rewir... Global synchronizability of duplex networks induced by three different intra-layer rewiring mechanisms is explored in this paper.The rewiring mechanisms are named as model-preserving rewiring(MPR), simply direct rewiring(SDR), and degree-preserving rewiring(DPR), respectively. It is found that high switching frequencies will certainly enhance global synchronizability for WSWS duplex networks(i.e., each layer is independently formed by the algorithm proposed by Watts and Strogatz for generating small-world networks), ER-ER duplex networks(i.e., each layer is independently generated by the algorithm proposed by Erd ¨os and Renyi) and BA-BA duplex networks(i.e., each layer is independently formed by the classical BA algorithm). Namely,the faster the intra-layer couplings are reconnected, the faster the duplex networks reach global synchronization. Furthermore,we find that by increasing the intra-or inter-coupling strengths, the WS-WS time-varying network’s global synchronizability is enhanced. Take the WS-WS time-varying network as an example, we find that SDR mechanism has greater impact on global synchronizability than MPR mechanism and DPR mechanism. The related dynamical networks can arrive at synchronization faster by SDR than by MPR or DPR. Thus, we only study the effects of SDR on ER-ER duplex networks and BA-BA duplex networks. In addition, we obtain the fact via numerical simulations that, switching intra-layer coupling topologies under SDR mechanism has the greatest impact on the BA-BA duplex network, followed by the ER-ER network, and has the weakest influence on the WS-WS duplex network in terms of improving the global synchronizability when all the intra-layer networks are sparse and have the same average degree. Finally, the global synchronizability of WS-WS and BA-BA time-varying networks is improved compared with static duplex networks, the reason being that the networks tend to be randomized under SDR according to analysis of the networks’ average clustering coefficients and degree distributions. 展开更多
关键词 multiplex network time-varying networks intra-layer connection SYNCHRONIZABILITY RECONNECTION
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