右美托咪定滴鼻对儿童七氟烷全麻苏醒期躁动的预防效果观察

目的观察分析右美托咪定滴鼻在预防小儿七氟烷全身麻醉(全麻)苏醒期躁动中的应用效果。方法 98例行全麻手术患儿,随机分为对照组与实验组,每组49例。两组患儿入室后均行七氟烷麻醉,实验组患儿手术结束前10 min经鼻滴入右美托咪定0.3μg/kg,对照组滴入等量的氯化钠注射液。对比两组患儿行麻醉处理后的手术情况、躁动发生情况、Ramsay评分以及视觉模拟评分法(VAS)评分。结果两组患儿手术时间、麻醉恢复室(PACU)停留时间比较差异无统计学意义(P>0.05);实验组患儿苏醒时间长于对照组,差异具有统计学意义(P<0.05)。实验组患儿躁动发生率为14.3%,显著低于对照组的38.8%,差异具有统计学意义(X^2=7.538, P<0.05)。拔出喉罩时(T1)、滴鼻结束后10 min(T2)时,实验组患儿Ramsay评分、VAS评分均显著低于对照组,差异具有统计学意义(P<0.05)。结论采用右美托咪定滴鼻,能够有效预防小儿七氟烷全麻苏醒期躁动的发生,改善患儿的预后,值得临床广泛推广应用。

熔融制样-X射线荧光光谱法测定锰铁、硅锰合金中锰硅磷

熔融制样-X射线荧光光谱法(XRF)测定合金样品,需重点解决样品前处理中合金样品侵蚀铂-黄金坩埚的难题。实验以无水四硼酸锂为熔剂,过氧化钡、碳酸锂为氧化剂,建立了熔融制样-X射线荧光光谱法测定锰铁、硅锰合金中锰、硅、磷含量的方法。实验方法采用低温预氧化熔融制样技术,解决了锰铁、硅锰合金对铂-黄金坩埚腐蚀的难题;应用碳烧失基和消去项消除了锰铁、硅锰合金中烧失/烧增量对检测结果的影响。试验进一步探讨了稀释比、氧化剂加入量、熔融温度、熔融时间等条件对锰铁、硅锰合金中锰、硅、磷含量的影响,得出最佳试验条件:稀释比(m无水四硼酸锂∶m试样)为7∶0.25;氧化剂量分别为过氧化钡0.500 0g、碳酸锂0.500 0g;熔融温度为1 100℃;静置熔融时间为150s。锰、硅、磷的方法检出限分别为10、25、18μg/g。在最佳实验条件下分别对锰铁(GSB03-1687-2004)、硅锰合金(GSB03-1316-2000)国家标准样品进行精密度考察,锰测定结果的相对标准偏差(RSD)分别为0.088%和0.053%(锰),0.35%和1.1%(硅),2.9%和1.2%(磷)。对于锰铁、硅锰合金实际样品,实验方法与国标方法的测定结果一致性较好,能满足常规分析要求。

林用整地圆盘耙结构分析及优化

对林用整地圆盘耙及耙组的构成、使用,耙深的调整及常出现的故障做了详细分析,并对圆盘耙结构进行了优化,介绍了耙组轴承的安装方法,对使用同类圆盘耙的人员具有很好的借鉴作用。

小剂量艾司氯胺酮对老年髋骨折患者术后早期认知功能的影响

目的观察小剂量艾司氯胺酮对髋骨折老年患者术后早期认知功能及S100β蛋白的影响。方法将60例拟在椎管内麻醉下行髋骨折手术的老年患者随机均分为2组,麻醉穿刺前15 min试验组给予艾司氯胺酮0.25 mg·kg^(-1)静脉注射,对照组给予等量氯化钠注射液。2组其他麻醉方案相同。观察患者生命体征变化,术前和术后1、2、3 d评估简易精神状态检查(MMSE)评分,检测血S100β蛋白浓度,并记录术后认知功能障碍(POCD)发生情况。结果2组患者平均动脉压(MAP)和心率(HR)均较平稳,麻醉穿刺时、手术开始时试验组MAP、HR均显著低于对照组(P<0.05)。与术前相比,2组术后MMSE评分均显著下降(P<0.05),术后1、2、3 d试验组MMSE评分均高于对照组,差异有显著意义(P<0.05)。术后2、3 d,试验组POCD发生率显著低于对照组(P<0.05)。2组术后S100β蛋白水平均较术前显著上升(P<0.05),术后1、2、3 d试验组S100β蛋白水平显著低于对照组(P<0.05)。结论艾司氯胺酮0.25 mg·kg^(-1)可减少髋骨折老年患者POCD的发生,可能与降低S100β蛋白水平有关。

An Unusual(3,11)-Connected Network Constructed by Tri-nuclear Lanthanide Building Units and Mixed Ligands

Under hydrothermal conditions,a new lanthanide coordination polymer,[Er3(oba)4(na)]n(1,oba=4,4?-oxybis(benzoate),na=nicotinic acid)has been synthesized.Compound 1 shows a 3D framework by incorporating tri-nuclear[Er3(COO)6]unit and the mixed ligands of oba2-and na-.It is interesting that decarboxylation occurred in the ortho position and 2,3-pyridinedicarboxylic acid was partially transformed into na under hydrothermal conditions.Compound 1 can be reduced into a(3,11)-connected net and displays weak second-harmonic generation response.Furthermore,the PXRD,TGA and IR spectra were also studied.

Luminescent Lanthanide-titanium-organic Compound Constructed by Tetra-nuclear Ln-Ti Building Units and Diphenylglycolic Acid

(Under solvothermal conditions with the mixed solvents of C_(2)H_(5)OH and H_(2)O,a new heterometallic lanthanide-titanium-organic compound,[TbTi(μ3-O)(L_(3))(H_(2)O)_(4)]·H_(3)O(1,H_(2)L=diphenylglycolic acid),has been synthesized.Compound 1 exhibits a 3D supramolecular framework by incorporating the tetra-nuclear[Tb_(2)Ti_(2)(μ3-O)2]unit and L^(2-)ligand.Compound 1 shows intense green luminescence.Furthermore,the PXRD,TGA and IR spectra were also studied.)

Luminescent Tetra-nuclear Lanthanide-titanium-organic Compound Obtained by the Mixed-ligand

A new heterometallic lanthanide-titanium-organic compound:[Eu_(2)Ti_(2)(dip)_(6)(dig)_(2)(H_(3)0)_(2)].solvent(1,dip=diphenylglycolic acid,dig=diglycolic acid)has been synthesized under solvothermal conditions.Compound 1 contains a tetra-nuclear{Eu_(2)Ti_(2)}unit with the mixed ligands of dip and dig.Compound 1 displays intense red luminescence.Furthermore,the IR,PXRD,UV-vis and TGA spectra were also studied.