AIM : To study the protective effects and the mechanisms of rofecoxib as a specific type 2 cyclooxygenase (COX- 2 inhibitor on focal cerebral ischemia reperfusion injury ( CIRI in rats. METHODS : The model of focal CI...AIM : To study the protective effects and the mechanisms of rofecoxib as a specific type 2 cyclooxygenase (COX- 2 inhibitor on focal cerebral ischemia reperfusion injury ( CIRI in rats. METHODS : The model of focal CIRI was induced by reversible middle cerebral artery occlusion ( MCAO with inserting a thread through internal carotid artery, 2 h occlusion展开更多
AIM. To observe apoptosis of the neurocytes and the expression of BCL-2 and BAX proteins after focal cerebral ischemia-reperfusion injury (CIRI) in brain tissue of rats and the protective effects of rofecoxib. METHODS...AIM. To observe apoptosis of the neurocytes and the expression of BCL-2 and BAX proteins after focal cerebral ischemia-reperfusion injury (CIRI) in brain tissue of rats and the protective effects of rofecoxib. METHODS: The model of local CIRI was induced by reversible middle cerebral artery occlusion ( MCAO with inserting a thread through internal展开更多
文摘AIM : To study the protective effects and the mechanisms of rofecoxib as a specific type 2 cyclooxygenase (COX- 2 inhibitor on focal cerebral ischemia reperfusion injury ( CIRI in rats. METHODS : The model of focal CIRI was induced by reversible middle cerebral artery occlusion ( MCAO with inserting a thread through internal carotid artery, 2 h occlusion
文摘AIM. To observe apoptosis of the neurocytes and the expression of BCL-2 and BAX proteins after focal cerebral ischemia-reperfusion injury (CIRI) in brain tissue of rats and the protective effects of rofecoxib. METHODS: The model of local CIRI was induced by reversible middle cerebral artery occlusion ( MCAO with inserting a thread through internal
