Background:Androgenic alopecia(AGA)is the most common type of hair loss in men,and there are many studies on the treatment of hair loss by platelet-rich plasma(PRP).The human scalp contains a huge microbiome,but its r...Background:Androgenic alopecia(AGA)is the most common type of hair loss in men,and there are many studies on the treatment of hair loss by platelet-rich plasma(PRP).The human scalp contains a huge microbiome,but its role in the process of hair loss remains unclear,and the relationship between PRP and the microbiome needs further study.Therefore,the purpose of this study was to investigate the effect of PRP treatment on scalp microbiota composition.Methods:We performed PRP treatment on 14 patients with AGA,observed their clinical efficacy,and collected scalp swab samples before and after treatment.The scalp microflora of AGA patients before and after treatment was characterized by amplifying the V3-V4 region of the 16 s RNA gene and sequencing for bacterial identification.Results:The results showed that PRP was effective in the treatment of AGA patients,and the hair growth increased significantly.The results of relative abundance analysis of microbiota showed that after treatment,g_Cutibacterium increased and g_Staphylococcus decreased,which played a stable role in scalp microbiota.In addition,g_Lawsonella decreased,indicating that the scalp oil production decreased after treatment.Conclusions:The findings suggest that PRP may play a role in treating AGA through scalp microbiome rebalancing.展开更多
Surfgrass Phyllospadix iwatensis is a dominant seagrass species along the east coast of Shandong Peninsula,China.Like other seagrasses in the world,surfgrass has been declining in the past decades.To assess the possib...Surfgrass Phyllospadix iwatensis is a dominant seagrass species along the east coast of Shandong Peninsula,China.Like other seagrasses in the world,surfgrass has been declining in the past decades.To assess the possibility of transplanting P.iwatensis in the coastal area,a new surfgrass transplant system was designed and applied to conduct a surfgrass transplantation experiment in a tide pool and a subtidal area,and its survival,morphological and physiological parameters were examined from May 2019 to June 2020.The results showed that after a year since transplantation,more than 65%of the transplants survived and the survival rate was higher in the subtidal site than in the tide pool.The morphological measurements including shoot height,leaf width,number of leaves per shoot,rhizome diameter and elongation rate,and number of roots per shoot were all higher in the subtidal area than in the tide pool,showing that the P.iwatensis transplants grew better in the subtidal area than in the tide pool in the study area.These results indicated that surfgrass can be transplanted in the two areas,and it is probably more suitable in subtidal area than in tide pool in the study area.展开更多
基金supported by the Guangdong Enterprise Joint Fund(No.2022A1515220137)The Shenzhen Science and Technology Innovation Committee(No.JCYJ20220530141615035)the Internal project of Huazhong University of Science and Technology Union Shenzhen Hospital(Nos.YN2021042 and YN2021045)。
文摘Background:Androgenic alopecia(AGA)is the most common type of hair loss in men,and there are many studies on the treatment of hair loss by platelet-rich plasma(PRP).The human scalp contains a huge microbiome,but its role in the process of hair loss remains unclear,and the relationship between PRP and the microbiome needs further study.Therefore,the purpose of this study was to investigate the effect of PRP treatment on scalp microbiota composition.Methods:We performed PRP treatment on 14 patients with AGA,observed their clinical efficacy,and collected scalp swab samples before and after treatment.The scalp microflora of AGA patients before and after treatment was characterized by amplifying the V3-V4 region of the 16 s RNA gene and sequencing for bacterial identification.Results:The results showed that PRP was effective in the treatment of AGA patients,and the hair growth increased significantly.The results of relative abundance analysis of microbiota showed that after treatment,g_Cutibacterium increased and g_Staphylococcus decreased,which played a stable role in scalp microbiota.In addition,g_Lawsonella decreased,indicating that the scalp oil production decreased after treatment.Conclusions:The findings suggest that PRP may play a role in treating AGA through scalp microbiome rebalancing.
基金supported by the National Key Research and Development Program of China(No.2019YFD0902101)the National Natural Science Foundation of China(No.42076100)the Fundamental Research Funds for the Central Universities(No.201964002).
文摘Surfgrass Phyllospadix iwatensis is a dominant seagrass species along the east coast of Shandong Peninsula,China.Like other seagrasses in the world,surfgrass has been declining in the past decades.To assess the possibility of transplanting P.iwatensis in the coastal area,a new surfgrass transplant system was designed and applied to conduct a surfgrass transplantation experiment in a tide pool and a subtidal area,and its survival,morphological and physiological parameters were examined from May 2019 to June 2020.The results showed that after a year since transplantation,more than 65%of the transplants survived and the survival rate was higher in the subtidal site than in the tide pool.The morphological measurements including shoot height,leaf width,number of leaves per shoot,rhizome diameter and elongation rate,and number of roots per shoot were all higher in the subtidal area than in the tide pool,showing that the P.iwatensis transplants grew better in the subtidal area than in the tide pool in the study area.These results indicated that surfgrass can be transplanted in the two areas,and it is probably more suitable in subtidal area than in tide pool in the study area.
