目的:总结分析经会阴三维超声扫描在盆底功能障碍性疾病中的诊断价值。方法:选择56例P F D(盆腔功能障碍性疾病)患者为观察组,另外选择同期体检盆腔功能正常的56例为对照组,均接受会阴三维超声,对比各组对象超声扫描不同状态下盆膈裂孔...目的:总结分析经会阴三维超声扫描在盆底功能障碍性疾病中的诊断价值。方法:选择56例P F D(盆腔功能障碍性疾病)患者为观察组,另外选择同期体检盆腔功能正常的56例为对照组,均接受会阴三维超声,对比各组对象超声扫描不同状态下盆膈裂孔前后径、左右径、面积、肛提肌厚度等。结果:①观察组患者缩肛状态、Valsalva动作、静息状态的肛提肌厚度情况有明显差异性;②发生PFD的观察组患者三种状态下的盆膈裂孔前后径、左右径、面积明显大于对照组,肛提肌厚度低于对照组,差异明显(P<0.05);③顺产组患者三种状态下盆膈裂孔前后径、左右径、面积明显大于剖宫产组,肛提肌厚度低于剖宫产组。结论:PFD患者不同状态下的盆腔膈裂孔形态、及肛提肌厚度与正常人有明显差异性,会阴三维超声扫描则能清楚显示盆膈裂孔情况,并能准确测量其面积及大小、肛提肌厚度,从而辅助诊断PFD。展开更多
This note reports simulation study on the rate of decay in linkage disequilibrium (LD) in mixed populations over multiple discrete generations and explores the usefulness of the LD analysis in high-resolution gene map...This note reports simulation study on the rate of decay in linkage disequilibrium (LD) in mixed populations over multiple discrete generations and explores the usefulness of the LD analysis in high-resolution gene mapping. The results indicate that the smaller the recombination fraction and the fewer generations since admixture event, the higher power of the approach in gene mapping. The expected estimate of recombination fraction would give an estimate that is slightly biased upwards, if relevant genes are in tight linkage. The estimated recombination fraction is usually larger than the true value within 2-5 generations. From generations 10-20, the mean estimates are in good agreement with the true value. The method presented here enables estimation of means and corresponding confidence intervals of the recombination fraction at any number of generations.展开更多
文摘目的:总结分析经会阴三维超声扫描在盆底功能障碍性疾病中的诊断价值。方法:选择56例P F D(盆腔功能障碍性疾病)患者为观察组,另外选择同期体检盆腔功能正常的56例为对照组,均接受会阴三维超声,对比各组对象超声扫描不同状态下盆膈裂孔前后径、左右径、面积、肛提肌厚度等。结果:①观察组患者缩肛状态、Valsalva动作、静息状态的肛提肌厚度情况有明显差异性;②发生PFD的观察组患者三种状态下的盆膈裂孔前后径、左右径、面积明显大于对照组,肛提肌厚度低于对照组,差异明显(P<0.05);③顺产组患者三种状态下盆膈裂孔前后径、左右径、面积明显大于剖宫产组,肛提肌厚度低于剖宫产组。结论:PFD患者不同状态下的盆腔膈裂孔形态、及肛提肌厚度与正常人有明显差异性,会阴三维超声扫描则能清楚显示盆膈裂孔情况,并能准确测量其面积及大小、肛提肌厚度,从而辅助诊断PFD。
文摘This note reports simulation study on the rate of decay in linkage disequilibrium (LD) in mixed populations over multiple discrete generations and explores the usefulness of the LD analysis in high-resolution gene mapping. The results indicate that the smaller the recombination fraction and the fewer generations since admixture event, the higher power of the approach in gene mapping. The expected estimate of recombination fraction would give an estimate that is slightly biased upwards, if relevant genes are in tight linkage. The estimated recombination fraction is usually larger than the true value within 2-5 generations. From generations 10-20, the mean estimates are in good agreement with the true value. The method presented here enables estimation of means and corresponding confidence intervals of the recombination fraction at any number of generations.