SIX1(OMIM 601205),as a member of the SIX homeobox transcription factor family,belongs to homologs of the Drosophila‘sine oculis’gene that expresses primarily in the developing visual system of the fly.The SIX family...SIX1(OMIM 601205),as a member of the SIX homeobox transcription factor family,belongs to homologs of the Drosophila‘sine oculis’gene that expresses primarily in the developing visual system of the fly.The SIX family includes six members(SIX1–SIX6),which share a homologous DNA-binding homeodomain(HD)and a highly conserved protein–protein interacting SIX domain(SD)[1].展开更多
基金supported by grants from National Natural Science Foundation of China[81700920,81970894,and81870725]Natural Science Foundation of Jiangsu Province[BK20191229,BK20180048,and 17KJA180008]+3 种基金the Fifth‘333Project’Scientific Research Foundation of Jiangsu Province[BRA2019192 and BRA2019278]Medical Scientific Research Project from Health and Family Planning Commission of Jiangsu Province[H201666]Shanghai Municipal Education Commission–Gaofeng Clinical Medicine Grant[20152519]Science and Technology Commission of Shanghai Municipality[14DZ2260300]。
文摘SIX1(OMIM 601205),as a member of the SIX homeobox transcription factor family,belongs to homologs of the Drosophila‘sine oculis’gene that expresses primarily in the developing visual system of the fly.The SIX family includes six members(SIX1–SIX6),which share a homologous DNA-binding homeodomain(HD)and a highly conserved protein–protein interacting SIX domain(SD)[1].
