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枳椇水提液改善慢性酒精性肝损伤作用研究 被引量:2
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作者 楚胜 李传俊 《智慧健康》 2019年第25期27-29,32,共4页
目的研究枳椇水提液改善酒精所致小鼠慢性肝损伤的作用。方法每日用56度白酒灌胃,建立小鼠慢性肝损伤模型,剂量10mL/kg,连续3周。选取40只小鼠,随机分为正常组,模型组,枳椇水提液低剂量组、枳椇水提液中剂量组、枳椇水提液高剂量组(1 mg... 目的研究枳椇水提液改善酒精所致小鼠慢性肝损伤的作用。方法每日用56度白酒灌胃,建立小鼠慢性肝损伤模型,剂量10mL/kg,连续3周。选取40只小鼠,随机分为正常组,模型组,枳椇水提液低剂量组、枳椇水提液中剂量组、枳椇水提液高剂量组(1 mg/mL、2 mg/mL、4 mg/mL),每组8只,枳椇低剂量组、枳椇中剂量组、枳椇高剂量组分别用1mg/mL、2mg/mL、4mg/mL枳椇水提液罐胃,1次/d,0.5 mL/次,连用15 d;正常组和模型组生理盐水罐胃,1次/d,0.5 mL/次,连用15 d,测定小鼠血清中AST、ALT、MDA,检测肝组织MDA、SOD活性分析小鼠肝损伤程度以及肝组织脂肪变性程度。结果与模型组相比,枳椇水提液各剂量组均降低血清ALT、AST含量,提高SOD活性,降低肝组织MDA的产生,阻止肝组织脂肪变性,尤以枳椇水提液高剂量组(4mg/mL)效果最明显。结论枳椇水提液高剂量组对慢性酒精性肝损伤具有保护作用,阻止肝组织脂肪变性进程,有利于慢性酒精性肝损伤者肝细胞修复。 展开更多
关键词 枳椇水提液 酒精性慢性肝损伤 保肝作用 抗氧化 肝组织脂肪变性
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Hybrid ToA and IMU indoor localization system by various algorithms 被引量:4
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作者 CHEN Xue-chen chu sheng +1 位作者 LI Fan chu Guang 《Journal of Central South University》 SCIE EI CAS CSCD 2019年第8期2281-2294,共14页
In this paper, we integrate inertial navigation system (INS) with wireless sensor network (WSN) to enhance the accuracy of indoor localization. Inertial measurement unit (IMU), the core of the INS, measures the accele... In this paper, we integrate inertial navigation system (INS) with wireless sensor network (WSN) to enhance the accuracy of indoor localization. Inertial measurement unit (IMU), the core of the INS, measures the accelerated and angular rotated speed of moving objects. Meanwhile, the ranges from the object to beacons, which are sensor nodes with known coordinates, are collected by time of arrival (ToA) approach. These messages are simultaneously collected and transmitted to the terminal. At the terminal, we set up the state transition models and observation models. According to them, several recursive Bayesian algorithms are applied to producing position estimations. As shown in the experiments, all of three algorithms do not require constant moving speed and perform better than standalone ToA system or standalone IMU system. And within them, two algorithms can be applied for the tracking on any path which is not restricted by the requirement that the trajectory between the positions at two consecutive time steps is a straight line. 展开更多
关键词 indoor localization time of arrival (ToA) inertial measurement unit (IMU) Bayesian filter extended Kalman filter MAP algorithm
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