To the Editor: Sepsis is one of the leading causes of death in Intensive Care Units. It is known as the syndrome of organ dysfunction caused by infection. Immune response has a critical role in sepsis. High concentra...To the Editor: Sepsis is one of the leading causes of death in Intensive Care Units. It is known as the syndrome of organ dysfunction caused by infection. Immune response has a critical role in sepsis. High concentrations of pro-inflammatory cytokines such as tumor necrosis factor alpha (TNF-α) and interleukin (IL)-6 have been suggested to be harmful and one of the major causes of organ injury.[1] Immune paralysis in sepsis causes a secondary infection.展开更多
基金This study was supported by grants from the National Natural Science Foundation of China (No. 81772051) and Zhejiang Provincial Natural Science Foundation of China (No. LQ16CI20001).
文摘To the Editor: Sepsis is one of the leading causes of death in Intensive Care Units. It is known as the syndrome of organ dysfunction caused by infection. Immune response has a critical role in sepsis. High concentrations of pro-inflammatory cytokines such as tumor necrosis factor alpha (TNF-α) and interleukin (IL)-6 have been suggested to be harmful and one of the major causes of organ injury.[1] Immune paralysis in sepsis causes a secondary infection.