Dear Editor,COVID-19 pandemic,caused by SARS-CoV-2 infection,is raging around the world and results in millions of deaths since the end of 2019.Although various therapies including vaccines and neutralizing antibodies...Dear Editor,COVID-19 pandemic,caused by SARS-CoV-2 infection,is raging around the world and results in millions of deaths since the end of 2019.Although various therapies including vaccines and neutralizing antibodies have been developed to defend against the horrible pandemic,current strategies are inevitably at risk of failure due to high mutagenicity of the viral genome.In fact,the most worrying situation is that the monoclonal antibodies of existing vaccines against the rapidly spreading Omicron variant are ineffective.展开更多
基金supported by grants from the National Key R&D Program and the National Natural Science Foundation of China(No.2017YFA0504504,22025702,82021003,91853203,82151211 to X.Deng,and 82073874 to L.Li)the Fundamental Research Funds for the Central Universities of China(No.20720200008 to X.Deng)+1 种基金Health Science and Technology Program of Fujian Province(No.2020CXB050 to J.Zheng)the Program of Introducing Talents of Discipline to Universities(111 Project,B06016).
文摘Dear Editor,COVID-19 pandemic,caused by SARS-CoV-2 infection,is raging around the world and results in millions of deaths since the end of 2019.Although various therapies including vaccines and neutralizing antibodies have been developed to defend against the horrible pandemic,current strategies are inevitably at risk of failure due to high mutagenicity of the viral genome.In fact,the most worrying situation is that the monoclonal antibodies of existing vaccines against the rapidly spreading Omicron variant are ineffective.
