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Serological Targeted Analysis of an ITIH4 Peptide Isoform: A Preterm Birth Biomarker and Its Associated SNP Implications 被引量:1
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作者 Zhou Tan Zhongkai Hu +12 位作者 Emily Y.Cai cantas alev Ting Yang Zhen Li Joyce Sung Yasser Yehia El-Sayed Gary M.Shaw David K.Stevenson Atul J.Butte Guojun Sheng Karl G.Sylvester Harvey J.Cohen Xuefeng B.Ling 《Journal of Genetics and Genomics》 SCIE CAS CSCD 2015年第9期507-510,共4页
Over 11% of all pregnancies in the US result in preterm birth, greatly contributing to perinatal morbidity and mortality (Goldenberg and Rouse, 1998). Preterm birth etiologies remain largely unknown, and effective p... Over 11% of all pregnancies in the US result in preterm birth, greatly contributing to perinatal morbidity and mortality (Goldenberg and Rouse, 1998). Preterm birth etiologies remain largely unknown, and effective prevention methods have yet to be developed. The use of biofluid (e.g., serum or urine) for the analysis of the naturally occurring peptidome (MW 〈 4000) as a source of biomarkers has been reported for different diseases (Villanueva et al., 2006; Ling et al., 2010a, 2010b, 2010c, 2011). Mass spectrometry-based profiling of naturally occurring peptides can provide an extensive in- ventory of serum peptides derived from either high-abundant endogenous circulating proteins or cell and tissue proteins (Liotta and Petricoin, 2006). 展开更多
关键词 Serological Targeted Analysis of an ITIH4 Peptide Isoform A Preterm Birth Biomarker and Its Associated SNP Implications SNP
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