Numerous studies have investigated the biosynthesis of pyridine heterocycles derived from nicotinic acid.How-ever,metabolic pathways generating pyridine heterocycles in nature remain uninvestigated.Here,we summarize r...Numerous studies have investigated the biosynthesis of pyridine heterocycles derived from nicotinic acid.How-ever,metabolic pathways generating pyridine heterocycles in nature remain uninvestigated.Here,we summarize recent contributions conducted in the last decade on the biosynthetic pathways of non-derivate from nicotinic acid pyridine rings and discuss their implication on the study of natural products with pyridine structures.展开更多
基金This work was supported by the Edison Biotechnology Institute(EBI)and the Baker Fund at Ohio University.
文摘Numerous studies have investigated the biosynthesis of pyridine heterocycles derived from nicotinic acid.How-ever,metabolic pathways generating pyridine heterocycles in nature remain uninvestigated.Here,we summarize recent contributions conducted in the last decade on the biosynthetic pathways of non-derivate from nicotinic acid pyridine rings and discuss their implication on the study of natural products with pyridine structures.
