Four new constituents from Taraxacum mongolicum

Two new flavone glycosides, isoetin-7-O-β-D-glucopyranosyl-2′-O-α-L-arabinopyranoside （1） and isoetin-7-O-β-D-glucopyranosyl-2′-O-α-D-glucopyranoside （2）, a new lignan, mongolicumin A （3）, and a new guaianolide, mongolicumin B （4） were isolated from the aerial part of Taraxacum mongolicum. Their structures were elucidated mainly by spectral analyses.

Two new compounds from Zingiber officinale

新周期的 diarylheptanoid， 1,5-epoxy-3-hydroxy-1-(3-methoxy-4,5-dihydroxyphenyl )-7-(4-hydroxyphenyl)-heptane (1 ) ，以及新单音的萜烯， 10-O- β - d-glucopyranosyl-hydroxy cineole (2 ) 从姜 officinale 的根茎被孤立。混合物的结构 1 和 2 被建立基于他们的光谱数据。另外，这些混合物的抗氧化剂活动也被测量。

Synthesis and Antioxidant Properties of Novel Silybin Analogues

八新奇 silybin 类似物(7a-h ) 被综合并且他们包括清除的能力的抗氧化剂性质 DPPH 自由基上的超级氧化物阴离子自由基和禁止的效果被决定。几合成混合物显示出可比较的抗氧化的效果到橡黄素的。

Four new eremophilendiolides from Ligularia atroviolacea

From Ligularia atroviolacea, four new eremophilendiolides, 81$-hydroxy-eremophil-3,7 （11）-dien-12,8α（14,6α）-diolide （1）, 8β-methoxy-eremophil-3,7（11）-dien-12,8α（14,6α）-diolide （2）, 8α-hydroxy-eremophil-3,7（11）-dien-12,8lβ（14,6α）-diolide （3） and eremophil-3,7（11）,8-trien-12,8 （14,6α）-diolide （4）, as well as a known diolide （5） were isolated. Their structures were elucidated on the basis of 1D and 2D NMR as well as ESI-MS spectral data.

Three new diarylheptanoids and their antioxidant property

Three new diarylheptanoids, i.e., sodium（5S,2E）- 1,7-bis（4-hydroxyphenyl）- 1-hydroxy-2-hepten-5 -sulfonate （1）, sodium（5R,2E）-1,7-bis（4-hydroxyphenyl）-1-hydroxy-2-hepten-5-sulfonate （2） and 3,5-diacetoxy-1-（3-methoxy-4,5-dihydroxyphenyl）-7-（4-hydroxy-3-methoxyphenyl）heptane （3） were isolated from the rhizomes of Zingiber officinale. The structures of the new compounds were elucidated on the basis of spectroscopic methods. The antioxidant activities of 3 were assayed by in vitro models involving DPPH free radicals and superoxide anion radicals.

Synthesis and Biological Evaluation of Pyranone Analogues of Territrem B

23 compounds containing pyranone pharmacophore of territrem B were designed and synthesized. Some of the analogues showed IC50 values of AChE inhibition at 10^-5 mol/L.

A new anti-diabetic sesquiterpenoid from Acorus calamus

新 sesquiterpenoid， 1,5-guaiane-4,10-diol-6-one (1 ) ，从 Acorus 省藤属的植物的根茎的 70% EtOH 摘录被孤立。结构在分光镜的方法上被决定，特别 2D NMR 技术。1 的绝对配置被它的 ECD 光谱的 TDDFT 量化学药品计算证实。在 HepG2 房间的一个调停胰岛素的葡萄糖消费模型上加重 1 项显示出的有希望的反糖尿病的活动。