目的探讨脂代谢异常人群亚临床甲状腺功能减退(SCH)的患病特点及危险因素。方法对甘肃省内2463例汉族成年居民进行调查,记录受试者一般资料、生化指标和甲状腺功能,χ^(2)检验分析脂代谢异常人群SCH的患病情况,logistic回归分析脂代谢...目的探讨脂代谢异常人群亚临床甲状腺功能减退(SCH)的患病特点及危险因素。方法对甘肃省内2463例汉族成年居民进行调查,记录受试者一般资料、生化指标和甲状腺功能,χ^(2)检验分析脂代谢异常人群SCH的患病情况,logistic回归分析脂代谢异常人群患SCH的危险因素。结果共纳入调查对象2463例(男1299例,女1164例),总人群中脂代谢异常503例,SCH患病538例。脂代谢异常人群中SCH患病率明显高于正常人群(26.64%vs 20.16%,P=0.004),SCH组年龄、体质量指数(BMI)、收缩压(SP)、舒张压(DP)、空腹血糖(FPG)、口服葡萄糖耐量试验(OGTT)负荷后2 h血糖(2 h PG)、总胆固醇(TG)、甘油三酯(TC)、低密度脂蛋白胆固醇(LDL-C)、谷草转氨酶(AST)、血磷(P)、糖化血红蛋白(HbA1c)、抗甲状腺过氧化物酶抗体(TPOAb)和抗甲状腺球蛋白抗体(TgAb)均高于正常组,尿酸(UA)低于正常组(均P<0.05)。TC和LDL-C水平正常、升高与异常3组间SCH患病率差异有统计学意义。Logistic回归分析显示,增龄、高SP、高FPG、高2 h PG为SCH的危险因素,男性为保护因素。结论脂代谢异常与SCH的发生密切相关,患病情况在女性中更为突出,应重视其防治。展开更多
Improving the mixing way of fillers and polymer before molding was demonstrated to be a promising approach in the past. In this study, we investigated the effects of the mixing method and the dispersed solvent on the ...Improving the mixing way of fillers and polymer before molding was demonstrated to be a promising approach in the past. In this study, we investigated the effects of the mixing method and the dispersed solvent on the mechanical and friction performance of halloysite nanotubes (HNTs)-filled polytetrafluoroethylene (PTFE) (HNTs/PTFE). After evenly mixing in solution, the HNTs/PTFE mixtures were formed into disc-like nanocomposites by the cold compression molding method. The mechanical performance showed that the tensile strength of the HNTs/PTFE nanocomposites prepared by employing the solution mixing method was about 3—5 MPa more and the Young’s modulus was increased by about 1.2 times greater than those prepared by employing the drying mixing method, but unfortunately they had a poorer elongation at break. Alternatively, it was noteworthy that the wear resistance of the nanocomposites prepared by employing the solution mixing method was improved by 5—10 times and 11—20 times as compared to those formed via the drying mixing method and pure PTFE, respectively. The results showed that the PTFE nanocomposites filled with HNTs by using the solution mixing method exhibited an excellent antiwear performance and had a desirable processability.展开更多
There are many great heroes in ancient Greek history.Some of them fought for their country,some for their honor,and some for special emotions.There three admirable heroes we know also fight with different purposes,the...There are many great heroes in ancient Greek history.Some of them fought for their country,some for their honor,and some for special emotions.There three admirable heroes we know also fight with different purposes,they are Achilles,Hector and Her-acles.Fight for what? For Achilles,Hector and Heracles there are different answers to this question.展开更多
目的探讨脂代谢异常人群甲状腺结节(TN)的检出情况及相关影响因素。方法于2016年9月4日至2017年2月1日在甘肃省兰州市、陇南市、定西市、临夏市抽取居住5年以上的社区居民作为调查对象。调查并记录一般情况,采集静脉血检测血脂相关生化...目的探讨脂代谢异常人群甲状腺结节(TN)的检出情况及相关影响因素。方法于2016年9月4日至2017年2月1日在甘肃省兰州市、陇南市、定西市、临夏市抽取居住5年以上的社区居民作为调查对象。调查并记录一般情况,采集静脉血检测血脂相关生化指标,并进行甲状腺超声检查。通过比较一般资料和生化指标,分析脂代谢异常和TN检出情况,并通过logistic回归分析脂代谢异常人群患TN的危险因素。结果本研究共纳入2059人(男性1049人、女性1010人),TN总检出率为23.17%(477/2059),脂代谢异常人群TN检出率[34.16%(151/442)]高于脂代谢正常人群[20.16%(326/1617),P<0.01],其中女性TN检出率[43.37%(85/196)]高于男性[26.83%(66/246),P<0.01]。脂代谢异常人群中TN检出率最高的是混合型高脂血症者[57.14%(16/28)],其次为高甘油三酯(TG)血症者[34.59%(92/266)]。总胆固醇(TC)、低密度脂蛋白(LDL-C)水平升高组的TN检出率[35.16%(32/91),34.85%(23/66)]均高于边缘升高组[27.04%(86/318),30.42%(73/240)]和正常组[21.76%(359/1650),21.73%(381/1753),P均<0.05]。logistic回归分析结果显示,年龄升高、空腹血糖升高(FPG)、口服葡萄糖耐量试验(OGTT)负荷后2 h血糖(2 h PG)升高、糖化血红蛋白(HbA1c)升高是脂代谢异常人群患TN的危险因素[比值比(OR)=1.065、1.387、1.866、1.384,P均<0.05]。结论脂代谢异常人群TN患病率较高;血糖和血脂水平的控制可能对预防TN发生有一定作用。展开更多
文摘目的探讨脂代谢异常人群亚临床甲状腺功能减退(SCH)的患病特点及危险因素。方法对甘肃省内2463例汉族成年居民进行调查,记录受试者一般资料、生化指标和甲状腺功能,χ^(2)检验分析脂代谢异常人群SCH的患病情况,logistic回归分析脂代谢异常人群患SCH的危险因素。结果共纳入调查对象2463例(男1299例,女1164例),总人群中脂代谢异常503例,SCH患病538例。脂代谢异常人群中SCH患病率明显高于正常人群(26.64%vs 20.16%,P=0.004),SCH组年龄、体质量指数(BMI)、收缩压(SP)、舒张压(DP)、空腹血糖(FPG)、口服葡萄糖耐量试验(OGTT)负荷后2 h血糖(2 h PG)、总胆固醇(TG)、甘油三酯(TC)、低密度脂蛋白胆固醇(LDL-C)、谷草转氨酶(AST)、血磷(P)、糖化血红蛋白(HbA1c)、抗甲状腺过氧化物酶抗体(TPOAb)和抗甲状腺球蛋白抗体(TgAb)均高于正常组,尿酸(UA)低于正常组(均P<0.05)。TC和LDL-C水平正常、升高与异常3组间SCH患病率差异有统计学意义。Logistic回归分析显示,增龄、高SP、高FPG、高2 h PG为SCH的危险因素,男性为保护因素。结论脂代谢异常与SCH的发生密切相关,患病情况在女性中更为突出,应重视其防治。
基金supported by the Talent Introduction Fund of Yangzhou University (2012)the Key Research Project-Industry Foresight and General Key Technology of Yangzhou (YZ2015020)+4 种基金the Innovative Talent Program of Green Yang Golden Phoenix (yzlyjfjh2015CX073)the Yangzhou Social Development Project (YZ2016072)the Jiangsu Province Six Talent Peaks Project (2014-XCL-013)the Jiangsu Industrial-Academic-Research Prospective Joint Project ( BY2016069-02)the Project Funded by the Priority Academic Program Development of Jiangsu Higher Education Institutions
文摘Improving the mixing way of fillers and polymer before molding was demonstrated to be a promising approach in the past. In this study, we investigated the effects of the mixing method and the dispersed solvent on the mechanical and friction performance of halloysite nanotubes (HNTs)-filled polytetrafluoroethylene (PTFE) (HNTs/PTFE). After evenly mixing in solution, the HNTs/PTFE mixtures were formed into disc-like nanocomposites by the cold compression molding method. The mechanical performance showed that the tensile strength of the HNTs/PTFE nanocomposites prepared by employing the solution mixing method was about 3—5 MPa more and the Young’s modulus was increased by about 1.2 times greater than those prepared by employing the drying mixing method, but unfortunately they had a poorer elongation at break. Alternatively, it was noteworthy that the wear resistance of the nanocomposites prepared by employing the solution mixing method was improved by 5—10 times and 11—20 times as compared to those formed via the drying mixing method and pure PTFE, respectively. The results showed that the PTFE nanocomposites filled with HNTs by using the solution mixing method exhibited an excellent antiwear performance and had a desirable processability.
文摘There are many great heroes in ancient Greek history.Some of them fought for their country,some for their honor,and some for special emotions.There three admirable heroes we know also fight with different purposes,they are Achilles,Hector and Her-acles.Fight for what? For Achilles,Hector and Heracles there are different answers to this question.
文摘目的探讨脂代谢异常人群甲状腺结节(TN)的检出情况及相关影响因素。方法于2016年9月4日至2017年2月1日在甘肃省兰州市、陇南市、定西市、临夏市抽取居住5年以上的社区居民作为调查对象。调查并记录一般情况,采集静脉血检测血脂相关生化指标,并进行甲状腺超声检查。通过比较一般资料和生化指标,分析脂代谢异常和TN检出情况,并通过logistic回归分析脂代谢异常人群患TN的危险因素。结果本研究共纳入2059人(男性1049人、女性1010人),TN总检出率为23.17%(477/2059),脂代谢异常人群TN检出率[34.16%(151/442)]高于脂代谢正常人群[20.16%(326/1617),P<0.01],其中女性TN检出率[43.37%(85/196)]高于男性[26.83%(66/246),P<0.01]。脂代谢异常人群中TN检出率最高的是混合型高脂血症者[57.14%(16/28)],其次为高甘油三酯(TG)血症者[34.59%(92/266)]。总胆固醇(TC)、低密度脂蛋白(LDL-C)水平升高组的TN检出率[35.16%(32/91),34.85%(23/66)]均高于边缘升高组[27.04%(86/318),30.42%(73/240)]和正常组[21.76%(359/1650),21.73%(381/1753),P均<0.05]。logistic回归分析结果显示,年龄升高、空腹血糖升高(FPG)、口服葡萄糖耐量试验(OGTT)负荷后2 h血糖(2 h PG)升高、糖化血红蛋白(HbA1c)升高是脂代谢异常人群患TN的危险因素[比值比(OR)=1.065、1.387、1.866、1.384,P均<0.05]。结论脂代谢异常人群TN患病率较高;血糖和血脂水平的控制可能对预防TN发生有一定作用。