BACKGROUND Granular cell tumor(GCT)of the pancreas is a rare neurogenic tumor.The first case of pancreatic GCT was described in 1975,and up to now,only 7 cases have been reported.CASE SUMMARY A 53-year-old male had a ...BACKGROUND Granular cell tumor(GCT)of the pancreas is a rare neurogenic tumor.The first case of pancreatic GCT was described in 1975,and up to now,only 7 cases have been reported.CASE SUMMARY A 53-year-old male had a pancreatic mass for 1 mo.He was not treated at the local hospital,but referred to Henan Tumor Hospital for surgery.Preoperative imaging revealed a 2.0 cm×2.5 cm-sized mass located in the body of the pancreas.At the microscopic level,a large number of eosinophilic particles are present in the oval tumor cells.The immunohistochemistry of this tumor cell display CD56(+),blood vessels CD34(+),Ki-67(+)<10%,and S-100(+).CONCLUSION GCT of the pancreas should be recognized as a preoperative differential diagnosis of pancreatic tumors.Surgical resection of the tumor should be attempted;however,GCT of the pancreas has a certain rate of tumor metastasis and recurrence.Therefore,GCT of the pancreas requires regular and long-term followup.展开更多
基金Supported by Henan Science and Technology Research Project,No.162102310045.
文摘BACKGROUND Granular cell tumor(GCT)of the pancreas is a rare neurogenic tumor.The first case of pancreatic GCT was described in 1975,and up to now,only 7 cases have been reported.CASE SUMMARY A 53-year-old male had a pancreatic mass for 1 mo.He was not treated at the local hospital,but referred to Henan Tumor Hospital for surgery.Preoperative imaging revealed a 2.0 cm×2.5 cm-sized mass located in the body of the pancreas.At the microscopic level,a large number of eosinophilic particles are present in the oval tumor cells.The immunohistochemistry of this tumor cell display CD56(+),blood vessels CD34(+),Ki-67(+)<10%,and S-100(+).CONCLUSION GCT of the pancreas should be recognized as a preoperative differential diagnosis of pancreatic tumors.Surgical resection of the tumor should be attempted;however,GCT of the pancreas has a certain rate of tumor metastasis and recurrence.Therefore,GCT of the pancreas requires regular and long-term followup.
