The development of fractured-vuggy carbonate reservoirs is extremely difficult because of the complex fractured-vuggy structure and strong heterogeneity.Foam flooding is a potential enhanced oil recovery(EOR)technolog...The development of fractured-vuggy carbonate reservoirs is extremely difficult because of the complex fractured-vuggy structure and strong heterogeneity.Foam flooding is a potential enhanced oil recovery(EOR)technology in fractured-vuggy carbonate reservoirs.Based on the similarity criterion,three types of 2D visual physical models of the fractured-vuggy structure were made by laser ablation technique,and a 3D visual physical model of the fractured-vuggy reservoir was made by 3D printing technology.Then the physical analog experiments of foam flooding were carried out in these models.The experimental results show that foam can effectively improve the mobility ratio,control the flow velocity of the fluid in different directions,and sweep complex fracture networks.The effect of foam flooding in fractures can be improved by increasing foam strength and enhancing foam stability.The effect of foam flooding in vugs can be improved by reducing the density of the foam and the interfacial tension between foam and oil.Three types of microscopic residual oil and three types of macroscopic residual oil can be displaced by foam flooding.This study verifies the EOR of foam flooding in the fractured-vuggy reservoir and provides theoretical support for the application of foam flooding in fractured-vuggy reservoirs.展开更多
Fault location for distribution feeders short circuit especially single-phase grounding fault is an important task in distribution system with non-effectively grounded neutral.Fault location mode for distribution feed...Fault location for distribution feeders short circuit especially single-phase grounding fault is an important task in distribution system with non-effectively grounded neutral.Fault location mode for distribution feeders using fault generated current and voltage transient traveling waves was investigated.The characteristics of transient traveling waves resulted from each short circuit fault and their transmission disciplinarian in distribution feeders are analyzed.This paper proposed that double end travelling waves theory which measures arriving time of fault initiated surge at both ends of the monitored line is fit for distribution feeders but single end traveling waves theory not.According to different distribution feeders,on the basis of analyzing original traveling waves reflection rule in line terminal, Current-voltage mode,voltage-voltage mode and current-current mode for fault location based on traveling waves are proposed and aerial mode component of original traveling waves is used to realize fault location.Experimental test verify the feasibility and correctness of the proposed method.展开更多
The ultrafast monitoring of deoxyribonucleic acid(DNA)dynamic structural changes is an emerging and rapidly growing research topic in biotechnology.The existing optical spectroscopy used to identify different dynamica...The ultrafast monitoring of deoxyribonucleic acid(DNA)dynamic structural changes is an emerging and rapidly growing research topic in biotechnology.The existing optical spectroscopy used to identify different dynamical DNA structures lacks quick response while requiring large consumption of samples and bulky instrumental facilities.It is highly demanded to develop an ultrafast technique that monitors DNA structural changes with the external stimulus or cancer-related disease scenarios.Here,we demonstrate a novel photonic integrated graphene-optofluidic device to monitor DNA structural changes with the ultrafast response time.Our approach is featured with an effective and straightforward design of decoding the electronic structure change of graphene induced by its interactions with DNAs in different conformations using ultrafast nanosecond pulse laser and achieving refractive index sensitivity of~3×10^(−5) RIU.This innovative technique for the first time allows us to perform ultrafast monitoring of the conformational changes of special DNA molecules structures,including G-quadruplex formation by K+ions and i-motif formation by the low pH stimulus.The graphene-optofluidic device as presented here provides a new class of label-free,ultrafast,ultrasensitive,compact,and cost-effective optical biosensors for medical and healthcare applications.展开更多
Wearable devices have received tremendous interests in human sweat analysis in the past few years.However,the widely used polymeric substrates and the layer-by-layer stacking structures greatly influence the cost-effi...Wearable devices have received tremendous interests in human sweat analysis in the past few years.However,the widely used polymeric substrates and the layer-by-layer stacking structures greatly influence the cost-efficiency,conformability and breathability of the devices,further hindering their practical applications.Herein,we report a facile and low-cost strategy for the fabrication of a skin-friendly thread/paper-based wearable system consisting of a sweat reservoir and a multi-sensing component for simultaneous in situ analysis of sweat pH and lactate.In the system,hydrophilic silk thread serves as the micro-channel to guide the liquid flow.Filter papers were functionalized to prepare colorimetric sensors for lactate and pH.The smartphone-based quantitative analysis shows that the sensors are sensitive and reliable.Although pH may interfere the lactate detection,the pH detected simultaneously could be employed to correct the measured data for the achievement of a precise lactate level.After being integrated with a hydrophobic arm guard,the system was successfully used for the on-body measurement of pH and lactate in the sweats secreted from the volunteers.This low-cost,easy-to-fabricate,light-weight and flexible thread/paper-based microfluidic sensing device may hold great potentials as a wearable system in human sweat analysis and point-of-care diagnostics.展开更多
基金supported by Project of Sinopec Northwest Oilfield Company(Grant No.202108ZB0046).
文摘The development of fractured-vuggy carbonate reservoirs is extremely difficult because of the complex fractured-vuggy structure and strong heterogeneity.Foam flooding is a potential enhanced oil recovery(EOR)technology in fractured-vuggy carbonate reservoirs.Based on the similarity criterion,three types of 2D visual physical models of the fractured-vuggy structure were made by laser ablation technique,and a 3D visual physical model of the fractured-vuggy reservoir was made by 3D printing technology.Then the physical analog experiments of foam flooding were carried out in these models.The experimental results show that foam can effectively improve the mobility ratio,control the flow velocity of the fluid in different directions,and sweep complex fracture networks.The effect of foam flooding in fractures can be improved by increasing foam strength and enhancing foam stability.The effect of foam flooding in vugs can be improved by reducing the density of the foam and the interfacial tension between foam and oil.Three types of microscopic residual oil and three types of macroscopic residual oil can be displaced by foam flooding.This study verifies the EOR of foam flooding in the fractured-vuggy reservoir and provides theoretical support for the application of foam flooding in fractured-vuggy reservoirs.
基金supported by Natural Science Foundation of Shandong Province(ZR2009FM054)
文摘Fault location for distribution feeders short circuit especially single-phase grounding fault is an important task in distribution system with non-effectively grounded neutral.Fault location mode for distribution feeders using fault generated current and voltage transient traveling waves was investigated.The characteristics of transient traveling waves resulted from each short circuit fault and their transmission disciplinarian in distribution feeders are analyzed.This paper proposed that double end travelling waves theory which measures arriving time of fault initiated surge at both ends of the monitored line is fit for distribution feeders but single end traveling waves theory not.According to different distribution feeders,on the basis of analyzing original traveling waves reflection rule in line terminal, Current-voltage mode,voltage-voltage mode and current-current mode for fault location based on traveling waves are proposed and aerial mode component of original traveling waves is used to realize fault location.Experimental test verify the feasibility and correctness of the proposed method.
基金from the National Natural Science Foundation of China(21874096,21575095,51602305,61604102 and 61875139)the 111 Project,and the Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD)+2 种基金the China Postdoctoral Science Foundation(2018M633118)Shenzhen Nanshan District Pilotage Team Program(LHTD20170006)Australian Research Council(ARC,FT150100450,IH150100006 and CE170100039).Q.Bao acknowledges support from the Australian Research Council(ARC)Centre of Excellence in Future Low-Energy Electronics Technologies(FLEET).
文摘The ultrafast monitoring of deoxyribonucleic acid(DNA)dynamic structural changes is an emerging and rapidly growing research topic in biotechnology.The existing optical spectroscopy used to identify different dynamical DNA structures lacks quick response while requiring large consumption of samples and bulky instrumental facilities.It is highly demanded to develop an ultrafast technique that monitors DNA structural changes with the external stimulus or cancer-related disease scenarios.Here,we demonstrate a novel photonic integrated graphene-optofluidic device to monitor DNA structural changes with the ultrafast response time.Our approach is featured with an effective and straightforward design of decoding the electronic structure change of graphene induced by its interactions with DNAs in different conformations using ultrafast nanosecond pulse laser and achieving refractive index sensitivity of~3×10^(−5) RIU.This innovative technique for the first time allows us to perform ultrafast monitoring of the conformational changes of special DNA molecules structures,including G-quadruplex formation by K+ions and i-motif formation by the low pH stimulus.The graphene-optofluidic device as presented here provides a new class of label-free,ultrafast,ultrasensitive,compact,and cost-effective optical biosensors for medical and healthcare applications.
基金supported by Chongqing Natural Science Foundation(cstc2019jcyj-msxmX0314)Fundamental Research Funds for the Central Universities(XDJK2019B002)Chongqing Engineering Research Center for Micro-Nano Biomedical Materials and Devices.
文摘Wearable devices have received tremendous interests in human sweat analysis in the past few years.However,the widely used polymeric substrates and the layer-by-layer stacking structures greatly influence the cost-efficiency,conformability and breathability of the devices,further hindering their practical applications.Herein,we report a facile and low-cost strategy for the fabrication of a skin-friendly thread/paper-based wearable system consisting of a sweat reservoir and a multi-sensing component for simultaneous in situ analysis of sweat pH and lactate.In the system,hydrophilic silk thread serves as the micro-channel to guide the liquid flow.Filter papers were functionalized to prepare colorimetric sensors for lactate and pH.The smartphone-based quantitative analysis shows that the sensors are sensitive and reliable.Although pH may interfere the lactate detection,the pH detected simultaneously could be employed to correct the measured data for the achievement of a precise lactate level.After being integrated with a hydrophobic arm guard,the system was successfully used for the on-body measurement of pH and lactate in the sweats secreted from the volunteers.This low-cost,easy-to-fabricate,light-weight and flexible thread/paper-based microfluidic sensing device may hold great potentials as a wearable system in human sweat analysis and point-of-care diagnostics.