Advances in self-powered sports monitoring sensors based on triboelectric nanogenerators

The new era of the internet of things brings great opportunities to the field of intelligent sports.The collection and analysis of sports data are becoming more intelligent driven by the widely-distributed sensing network system.Triboelectric nanogenerators(TENGs)can collect and convert energy as selfpowered sensors,overcoming the limitations of external power supply,frequent power replacement and high-cost maintenance.Herein,we introduce the working modes and principles of TENGs,and then summarize the recent advances in self-powered sports monitoring sensors driven by TENGs in sports equipment facilities,wearable equipment and competitive sports specialities.We discuss the existing issues,i.e.,device stability,material sustainability,device design rationality,textile TENG cleanability,sports sensors safety,kinds and manufacturing of sports sensors,and data collection comprehensiveness,and finally,propose the countermeasures.This work has practical significance to the current TENG applications in sports monitoring,and TENG-based sensing technology will have a broad prospect in the field of intelligent sports in the future.

Multidisciplinary management of recurrent and metastatic hepatocellular carcinoma after resection: an international expert consensus

Hepatocellular carcinoma (HCC) is the sixth-most common cancer and the third leading cause of cancer-related death in the world. However, 40–70% patients eventually suffer from postoperative recurrence within 5 years. HCC recurrence after surgery severely affects prognosis of the patients. Nevertheless, there is an opportunity to improve patients' prognosis if doctors and researchers can recognize the importance of a standardized perioperative management and study it in clinical and pre-clinical settings. Hence, based on our own experience and published studies from other researchers, we develop this consensus regarding multidisciplinary management of locally recurrent and metastatic hepatocellular carcinoma after resection. This consensus consists of the entire course of recurrent hepatocellular carcinoma (RHCC) management, including prediction of recurrence, prevention, diagnosis, treatment and surveillance of RHCC. Consensus recommendations are presented with grades of evidences (Ia, Ib, IIa, IIb, III and IV), and strength ofrecommendations (A, B, C, D and E). We also develop a decision-making path for RHCC treatment, which can intuitively demonstrate the management for RHCC. It is hoped that we may make some effort to standardize the management of RHCC and ultimately understand how to improve outcomes.

A giant primary hepatic low-grade malignant mesenchymal tumor of the liver in a teenager

A 14-year-old girl presented with right upper abdominal swelling for two months.Physical examination revealed palpable hepatomegaly.Her laboratory analysis revealed a mild anemia(HGB:108 g/L).The tests for liver function were normal.The Child-Pugh score was A grade.The tests for hepatitis B and C viruses were negative.The tests for tumor markers such as carcinoembryonic antigen(CEA),α-fetoprotein(AFP),and cancer antigen 19-9(CA19-9)were normal.All other laboratory results were within the normal range.Abdominal ultrasound revealed an oval isoechoic mass in the liver measuring 26.4 cm×25.6 cm×12.6 cm,which was solid,ill-defined and had rich blood flow signals.Contrast-enhanced CT and MRI of the liver demonstrated a huge hepatic mass of 14.4 cm×21.5 cm×22.2 cm,and heterogenous enhancement with central necrosis,which involved all three hepatic veins,the left portal vein and had loss of fat planes with the inferior vena cava(Figure 1A,B).Three-dimensional reconstruction technology revealed that the total hepatic volume was 6,158.3 mL,and the tumor volume was 4,258.68 mL.Furthermore,the standard hepatic volume was 1,105 mL,the remnant liver volume was 1,373 mL(72%),and the indocyanine green clearance test at 15 minutes was 1.2%.