To investigate the effect of void defects on the shock response of hexanitrohexaazaisowurtzitane(CL-20)co-crystals,shock responses of CL-20 co-crystals with energetic materials ligands trinitrotoluene(TNT),1,3-dinitro...To investigate the effect of void defects on the shock response of hexanitrohexaazaisowurtzitane(CL-20)co-crystals,shock responses of CL-20 co-crystals with energetic materials ligands trinitrotoluene(TNT),1,3-dinitrobenzene(DNB),solvents ligands dimethyl carbonate(DMC) and gamma-butyrolactone(GBL)with void were simulated,using molecular dynamics method and reactive force field.It is found that the CL-20 co-crystals with void defects will form hot spots when impacted,significantly affecting the decomposition of molecules around the void.The degree of molecular fragmentation is relatively low under the reflection velocity of 2 km/s,and the main reactions are the formation of dimer and the shedding of nitro groups.The existence of voids reduces the safety of CL-20 co-crystals,which induced the sensitivity of energetic co-crystals CL-20/TNT and CL-20/DNB to increase more significantly.Detonation has occurred under the reflection velocity of 4 km/s,energetic co-crystals are easier to polymerize than solvent co-crystals,and are not obviously affected by voids.The results show that the energy of the wave decreases after sweeping over the void,which reduces the chemical reaction frequency downstream of the void and affects the detonation performance,especially the solvent co-crystals.展开更多
Fly fire is an elite variety of North American Begonia（ Malus micromalus）,which is characterized with dark red flowers,red young leaves,red peel,red bark,large flower amount,long flowering period and long fruit bear...Fly fire is an elite variety of North American Begonia（ Malus micromalus）,which is characterized with dark red flowers,red young leaves,red peel,red bark,large flower amount,long flowering period and long fruit bearing period. It is propagated mainly through grafting,and is suitable for popularization and application in the landscape of the Yangtze River basin and north of the Yangtze River.展开更多
A novel layered perovskite tantalate phosphor Sr_(3)LaTa_(3)O_(12):Sm^(3+)(SLTO:Sm^(3+)) with orange-red emission was obtained for the first time via the solid-phase synthetic method. The phase purity, surface morphol...A novel layered perovskite tantalate phosphor Sr_(3)LaTa_(3)O_(12):Sm^(3+)(SLTO:Sm^(3+)) with orange-red emission was obtained for the first time via the solid-phase synthetic method. The phase purity, surface morphology,element distribution and luminescent properties of the SLTO:xSm^(3+)(x= 0.01 mol%-0.30 mol%) phosphors were investigated. Under 408 nm excitation, the optimum doped SLTO:0.10Sm^(3+) phosphor emits orangered light at 598 nm with the highest emission peak(4G_(5/2)→6H_(7/2)). The critical energy transfer distance is 1.687 nm. The prepared SLTO:0.10Sm^(3+)phosphor has excellent thermal stability with temperature quenching temperature(T_(0.5)> 500 K) and high activation energy(E_(a)= 0.25 e V). Through calculation, the chromaticity coordinates of all samples are concentrated in the orange-red area, and the color purity reaches 99%. The fabricated white light-emitting diode(w-LED) has a good correlated color temperature(5132 K), a high R_(a)(89), and the CIE chromaticity coordinates(0.340, 0.327). Consequently, the superiority of orange-red-emitting tantalate SLTO:Sm^(3+) phosphors for w-LEDs is demonstrated.展开更多
Since the beginning of grape cultivation in the 1980 s in Wuhan City,the grape industry has shown a steady growth trend. Through the survey of the local grape industry,it found out the regional distribution,scale and ...Since the beginning of grape cultivation in the 1980 s in Wuhan City,the grape industry has shown a steady growth trend. Through the survey of the local grape industry,it found out the regional distribution,scale and benefits of the grape,as well as the variety structure and cultivation management mode. It analyzed main problems in the grape production,including low degree of organization,concentrated maturity,low rate of good fruit,small cultivation scale,and low labor-saving and high-efficiency cultivation technologies. On the basis of the development status,it came up with pertinent recommendations,including optimizing the variety structure,implementing standardized management,strengthening construction of sightseeing parks,promoting integration of primary and tertiary industries,and developing the gardening experience,to promote healthy and sustainable development of the grape industry.展开更多
Noxious stimuli cause pain by activating cutaneous nociceptors.The Aδ-and C-fibers of dorsal root ganglion(DRG) neurons convey the nociceptive signals to the laminae Ⅰ—Ⅱ of spinal cord.In the dorsal horn of spinal...Noxious stimuli cause pain by activating cutaneous nociceptors.The Aδ-and C-fibers of dorsal root ganglion(DRG) neurons convey the nociceptive signals to the laminae Ⅰ—Ⅱ of spinal cord.In the dorsal horn of spinal cord,the excitatory afferent synaptic transmission is regulated by the inhibitory neurotransmitter γ-aminobutyric acid and modulators such as opioid peptides released from the spinal interneurons,and by serotonin,norepinepherine and dopamine from the descending inhibitory system.In contrast to the accumulated evidence for these central inhibitors and their neural circuits in the dorsal spinal cord,the knowledge about the endogenous suppressive mechanisms in nociceptive DRG neurons remains very limited.In this review,we summarize our recent findings of the presynaptic suppressive mechanisms in nociceptive neurons,the BNP/NPR-A/PKG/BK_(Ca) channel pathway,the FSTL1/α1Na^+-K^+ ATPase pathway and the activin C/ERK pathway.These endogenous suppressive systems in the mechanoheat nociceptors may also contribute differentially to the mechanisms of nerve injury-induced neuropathic pain or inflammation-induced pain.展开更多
Different physical and chemical stimuli are detected by the peripheral sensory receptors of dorsal root ganglion （DRG） neurons, and the generated inputs are transmitted via afferent fibers into the central nervous s...Different physical and chemical stimuli are detected by the peripheral sensory receptors of dorsal root ganglion （DRG） neurons, and the generated inputs are transmitted via afferent fibers into the central nervous system. The gene expression profiles of DRG neurons contribute to the generation, transmission, and regulation of various somatosensory signals. Recently, the single-cell transcriptomes, cell types, and functional annotations of somatosensory neurons have been studied. In this review, we introduce our classification of DRG neurons based on single-cell RNA-sequencing and functional analyses, and discuss the technical approaches. Moreover, studies on the molecular and cellular mechanisms underlying somatic sensations are discussed.展开更多
The flagship species conservation strategy is widely practiced in nature reserves.However,few studies have quantitatively explored whether the current functional zoning adequately conserves the habitats of other speci...The flagship species conservation strategy is widely practiced in nature reserves.However,few studies have quantitatively explored whether the current functional zoning adequately conserves the habitats of other species.To examine this problem,we selected the Tangjiahe,Xuebaoding,and Wanglang national nature reserves in southwest China and tested the protective efficiency of the giant panda(Ailuropoda melanoleuca)reserves on a local herbivore—Sichuan takin(Budorcas taxicolor tibetana)in functional zoning.We predicted that the habitat distribution of the Sichuan takin with Maxent and habitat suitability would be classified as very low,low,moderately,or highly suitable.We calculated the percentage of each type of habitat class across the core,buffer,and experimental zones in these reserves and introduced an economic index present value index to further assess the efficacy of the functional zoning in conserving the habitat of Sichuan takin.Our findings indicate that suitable habitat distributions of Sichuan takin are multicore and influenced by diverse variables in different nature reserves.The percentage of moderately suitable and highly suitable habitat in the core zone is 69%and 54%in Tangjiahe,76%and 75%in Wanglang,and 47%and 28%in Xuebaoding,respectively.The present value index of moderately and highly suitable habitat is 1.01 and 0.79(Tangjiahe),0.87 and 0.86(Wanglang),0.76 and 0.44(Xuebaoding),respectively.The efficiency of functional zoning on Sichuan takin seems lower than imagined in giant panda reserves,and species that have important impacts on local ecosystem need further estimation and greater focus.展开更多
Abundant tourism user-generated content(UGC)contains a wealth of cognitive and emotional in-formation,providing valuable data for building destination images that depict tourists’experiences and appraisal of the dest...Abundant tourism user-generated content(UGC)contains a wealth of cognitive and emotional in-formation,providing valuable data for building destination images that depict tourists’experiences and appraisal of the destinations during the tours.In particular,multiple destination images can assist tourism managers in exploring the commonalities and differences to investigate the elements of interest of tourists and improve the competitiveness of the destinations.However,existing methods usually focus on the image of a single destination,and they are not adequate to analyze and visualize UGC to extract valuable information and knowledge.Therefore,we discuss requirements with tourism experts and present MDIVis,a multi-level interactive visual analytics system that allows analysts to comprehend and analyze the cognitive themes and emotional experiences of multiple destination images for comparison.Specifically,we design a novel sentiment matrix view to summarize multiple destination images and improve two classic views to analyze the time-series pattern and compare the detailed information of images.Finally,we demonstrate the utility of MDIVis through three case studies with domain experts on real-world data,and the usability and effectiveness are confirmed through expert interviews.展开更多
基金supported by the National Natural Science Foundation of China (22275018)the Project of State Key Laboratory of Explosion Science and Technology (Beijing Institute of Technology)(Grant No.QNKT20-04)。
文摘To investigate the effect of void defects on the shock response of hexanitrohexaazaisowurtzitane(CL-20)co-crystals,shock responses of CL-20 co-crystals with energetic materials ligands trinitrotoluene(TNT),1,3-dinitrobenzene(DNB),solvents ligands dimethyl carbonate(DMC) and gamma-butyrolactone(GBL)with void were simulated,using molecular dynamics method and reactive force field.It is found that the CL-20 co-crystals with void defects will form hot spots when impacted,significantly affecting the decomposition of molecules around the void.The degree of molecular fragmentation is relatively low under the reflection velocity of 2 km/s,and the main reactions are the formation of dimer and the shedding of nitro groups.The existence of voids reduces the safety of CL-20 co-crystals,which induced the sensitivity of energetic co-crystals CL-20/TNT and CL-20/DNB to increase more significantly.Detonation has occurred under the reflection velocity of 4 km/s,energetic co-crystals are easier to polymerize than solvent co-crystals,and are not obviously affected by voids.The results show that the energy of the wave decreases after sweeping over the void,which reduces the chemical reaction frequency downstream of the void and affects the detonation performance,especially the solvent co-crystals.
基金Supported by Innovation Projects of Wuhan Academy of Agricultural Sciences(Cx201317Cxfzx201506Cxtd201507)
文摘Fly fire is an elite variety of North American Begonia（ Malus micromalus）,which is characterized with dark red flowers,red young leaves,red peel,red bark,large flower amount,long flowering period and long fruit bearing period. It is propagated mainly through grafting,and is suitable for popularization and application in the landscape of the Yangtze River basin and north of the Yangtze River.
基金Project supported by the Hunan Provincial Key Laboratory of Xiangnan Rare-Precious Metals Compounds and Applications(2019XGJSKFJJ01)the Construction Program of the Key Discipline of the Education Department in Hunan Province(18A465)+1 种基金the Natural Science Foundation of Hunan Province(2023JJ31000)the Natural Science Foundation of Shaanxi Province(2022NY-224)。
文摘A novel layered perovskite tantalate phosphor Sr_(3)LaTa_(3)O_(12):Sm^(3+)(SLTO:Sm^(3+)) with orange-red emission was obtained for the first time via the solid-phase synthetic method. The phase purity, surface morphology,element distribution and luminescent properties of the SLTO:xSm^(3+)(x= 0.01 mol%-0.30 mol%) phosphors were investigated. Under 408 nm excitation, the optimum doped SLTO:0.10Sm^(3+) phosphor emits orangered light at 598 nm with the highest emission peak(4G_(5/2)→6H_(7/2)). The critical energy transfer distance is 1.687 nm. The prepared SLTO:0.10Sm^(3+)phosphor has excellent thermal stability with temperature quenching temperature(T_(0.5)> 500 K) and high activation energy(E_(a)= 0.25 e V). Through calculation, the chromaticity coordinates of all samples are concentrated in the orange-red area, and the color purity reaches 99%. The fabricated white light-emitting diode(w-LED) has a good correlated color temperature(5132 K), a high R_(a)(89), and the CIE chromaticity coordinates(0.340, 0.327). Consequently, the superiority of orange-red-emitting tantalate SLTO:Sm^(3+) phosphors for w-LEDs is demonstrated.
基金Agricultural Science Innovation Project of Wuhan City"Demonstration and Extension of Grape,Citrus and Other Fruit Tree Facilities Cultivation Technologies and Green Prevention and Control"(CXQYDJ201804)
文摘Since the beginning of grape cultivation in the 1980 s in Wuhan City,the grape industry has shown a steady growth trend. Through the survey of the local grape industry,it found out the regional distribution,scale and benefits of the grape,as well as the variety structure and cultivation management mode. It analyzed main problems in the grape production,including low degree of organization,concentrated maturity,low rate of good fruit,small cultivation scale,and low labor-saving and high-efficiency cultivation technologies. On the basis of the development status,it came up with pertinent recommendations,including optimizing the variety structure,implementing standardized management,strengthening construction of sightseeing parks,promoting integration of primary and tertiary industries,and developing the gardening experience,to promote healthy and sustainable development of the grape industry.
基金supported by National Natural Science Foundation of China(31630033,31130066,31671094,81300961)Chinese Academy of Sciences(XDB02010000,QYZDY-SSW-SMC007)Shanghai Science and Technology Committee(16JC1420500)
文摘Noxious stimuli cause pain by activating cutaneous nociceptors.The Aδ-and C-fibers of dorsal root ganglion(DRG) neurons convey the nociceptive signals to the laminae Ⅰ—Ⅱ of spinal cord.In the dorsal horn of spinal cord,the excitatory afferent synaptic transmission is regulated by the inhibitory neurotransmitter γ-aminobutyric acid and modulators such as opioid peptides released from the spinal interneurons,and by serotonin,norepinepherine and dopamine from the descending inhibitory system.In contrast to the accumulated evidence for these central inhibitors and their neural circuits in the dorsal spinal cord,the knowledge about the endogenous suppressive mechanisms in nociceptive DRG neurons remains very limited.In this review,we summarize our recent findings of the presynaptic suppressive mechanisms in nociceptive neurons,the BNP/NPR-A/PKG/BK_(Ca) channel pathway,the FSTL1/α1Na^+-K^+ ATPase pathway and the activin C/ERK pathway.These endogenous suppressive systems in the mechanoheat nociceptors may also contribute differentially to the mechanisms of nerve injury-induced neuropathic pain or inflammation-induced pain.
基金supported by grants from the National Natural Science Foundation of China(31630033,31130066,31671094,and 81300961)the Chinese Academy of Sciences(XDB02010000 and QYZDY-SSW-SMC007)the Shanghai Science and Technology Committee(16JC1420500)
文摘Different physical and chemical stimuli are detected by the peripheral sensory receptors of dorsal root ganglion （DRG） neurons, and the generated inputs are transmitted via afferent fibers into the central nervous system. The gene expression profiles of DRG neurons contribute to the generation, transmission, and regulation of various somatosensory signals. Recently, the single-cell transcriptomes, cell types, and functional annotations of somatosensory neurons have been studied. In this review, we introduce our classification of DRG neurons based on single-cell RNA-sequencing and functional analyses, and discuss the technical approaches. Moreover, studies on the molecular and cellular mechanisms underlying somatic sensations are discussed.
基金Our research was funded by open project(ESP15004)from the Ecological Security and Protection Key Laboratory of Sichuan Province,Mianyang Normal University.
文摘The flagship species conservation strategy is widely practiced in nature reserves.However,few studies have quantitatively explored whether the current functional zoning adequately conserves the habitats of other species.To examine this problem,we selected the Tangjiahe,Xuebaoding,and Wanglang national nature reserves in southwest China and tested the protective efficiency of the giant panda(Ailuropoda melanoleuca)reserves on a local herbivore—Sichuan takin(Budorcas taxicolor tibetana)in functional zoning.We predicted that the habitat distribution of the Sichuan takin with Maxent and habitat suitability would be classified as very low,low,moderately,or highly suitable.We calculated the percentage of each type of habitat class across the core,buffer,and experimental zones in these reserves and introduced an economic index present value index to further assess the efficacy of the functional zoning in conserving the habitat of Sichuan takin.Our findings indicate that suitable habitat distributions of Sichuan takin are multicore and influenced by diverse variables in different nature reserves.The percentage of moderately suitable and highly suitable habitat in the core zone is 69%and 54%in Tangjiahe,76%and 75%in Wanglang,and 47%and 28%in Xuebaoding,respectively.The present value index of moderately and highly suitable habitat is 1.01 and 0.79(Tangjiahe),0.87 and 0.86(Wanglang),0.76 and 0.44(Xuebaoding),respectively.The efficiency of functional zoning on Sichuan takin seems lower than imagined in giant panda reserves,and species that have important impacts on local ecosystem need further estimation and greater focus.
基金This work was supported by the Chengdu Science and Tech-nology Bureau,China(Grant No.2019-YF05-02121-SN).
文摘Abundant tourism user-generated content(UGC)contains a wealth of cognitive and emotional in-formation,providing valuable data for building destination images that depict tourists’experiences and appraisal of the destinations during the tours.In particular,multiple destination images can assist tourism managers in exploring the commonalities and differences to investigate the elements of interest of tourists and improve the competitiveness of the destinations.However,existing methods usually focus on the image of a single destination,and they are not adequate to analyze and visualize UGC to extract valuable information and knowledge.Therefore,we discuss requirements with tourism experts and present MDIVis,a multi-level interactive visual analytics system that allows analysts to comprehend and analyze the cognitive themes and emotional experiences of multiple destination images for comparison.Specifically,we design a novel sentiment matrix view to summarize multiple destination images and improve two classic views to analyze the time-series pattern and compare the detailed information of images.Finally,we demonstrate the utility of MDIVis through three case studies with domain experts on real-world data,and the usability and effectiveness are confirmed through expert interviews.
