What is the most favorite and original chemistry developed in your research group?Our research focuses on the field of asymmetric organocatalysis and natural product synthesis.Our work draws upon and impacts the desig...What is the most favorite and original chemistry developed in your research group?Our research focuses on the field of asymmetric organocatalysis and natural product synthesis.Our work draws upon and impacts the design and synthesis of N-and P-containing bifunctional ion pair catalysts from a-amino acids,and their applications as organocatalysts or ligands in asymmetric synthesis.展开更多
Multiple hydrogen bonds containing nucleophilic phosphines derived from dipeptide dual-reagents catalyzed asymmetric Michael addition reactions between indene esters and activated olefins in high yields and good to ex...Multiple hydrogen bonds containing nucleophilic phosphines derived from dipeptide dual-reagents catalyzed asymmetric Michael addition reactions between indene esters and activated olefins in high yields and good to excellent enantioselectivities under mild reaction conditions.The success of current highly selective reactions should provide inspiration for expansion to other reactions and would open up new paradigms for the synthesis of indanone derivatives bearing chiral quaternary carbon centers.展开更多
文摘What is the most favorite and original chemistry developed in your research group?Our research focuses on the field of asymmetric organocatalysis and natural product synthesis.Our work draws upon and impacts the design and synthesis of N-and P-containing bifunctional ion pair catalysts from a-amino acids,and their applications as organocatalysts or ligands in asymmetric synthesis.
基金Financial support from Chinese Academy of Sciences (No.XDB 20020100)the National Natural Science Foundation of China (Nos.21572247,21871282) is gratefully acknowledged。
文摘Multiple hydrogen bonds containing nucleophilic phosphines derived from dipeptide dual-reagents catalyzed asymmetric Michael addition reactions between indene esters and activated olefins in high yields and good to excellent enantioselectivities under mild reaction conditions.The success of current highly selective reactions should provide inspiration for expansion to other reactions and would open up new paradigms for the synthesis of indanone derivatives bearing chiral quaternary carbon centers.
