COVID-19 is a major event with worldwide influences.Since the beginning of the epidemic,pharmaceutical chemists have paid attention to the therapeutic effect of a variety of small molecule medicines on COVID-19 infect...COVID-19 is a major event with worldwide influences.Since the beginning of the epidemic,pharmaceutical chemists have paid attention to the therapeutic effect of a variety of small molecule medicines on COVID-19 infection.A series of organic molecules are designed and found to be effective in the treatment of COVID-19 infection.In fact,no matter how effective they are,with the development of the COVID-19 epidemic,various small molecule medicines are gradually recognized by people.This is equivalent to a good science popularization of pharmaceutical chemistry.This review aims to introduce the molecules for COVID-19 treatment on the basis of their chemical structures,synthetic methods as well as their effects.展开更多
基金Natural Science Foundation of Hubei Province(No.2022CFB008)the Open Fund Project of Hubei Key Laboratory of Radiation Chemistry and Functional Materials(No.2021KF07)+1 种基金the fund of the joint-laboratory of Shanghai Dingya Pharmaceutical Chemical Technology Co.,Ltd.with Yangzhou University(2022-2027)Priority Academic Program Development of Jiangsu Higher Education Institution for support。
文摘COVID-19 is a major event with worldwide influences.Since the beginning of the epidemic,pharmaceutical chemists have paid attention to the therapeutic effect of a variety of small molecule medicines on COVID-19 infection.A series of organic molecules are designed and found to be effective in the treatment of COVID-19 infection.In fact,no matter how effective they are,with the development of the COVID-19 epidemic,various small molecule medicines are gradually recognized by people.This is equivalent to a good science popularization of pharmaceutical chemistry.This review aims to introduce the molecules for COVID-19 treatment on the basis of their chemical structures,synthetic methods as well as their effects.