Deep learning enhanced NIR-Ⅱ volumetric imaging of whole mice vasculature

Fluorescence imaging through the second near-infrared window(NIR-Ⅱ,1000–1700 nm) allows in-depth imaging.However, current imaging systems use wide-field illumination and can only provide low-contrast 2D information, without depth resolution. Here, we systematically apply a light-sheet illumination, a time-gated detection, and a deep-learning algorithm to yield high-contrast high-resolution volumetric images. To achieve a large Fo V(field of view) and minimize the scattering effect, we generate a light sheet as thin as 100.5 μm with a Rayleigh length of 8 mm to yield an axial resolution of 220 μm. To further suppress the background, we time-gate to only detect long lifetime luminescence achieving a high contrast of up to 0.45 Icontrast. To enhance the resolution, we develop an algorithm based on profile protrusions detection and a deep neural network and distinguish vasculature from a low-contrast area of 0.07 Icontrast to resolve the 100μm small vessels. The system can rapidly scan a volume of view of 75 × 55 × 20 mm3and collect 750 images within 6mins. By adding a scattering-based modality to acquire the 3D surface profile of the mice skin, we reveal the whole volumetric vasculature network with clear depth resolution within more than 1 mm from the skin. High-contrast large-scale 3D animal imaging helps us expand a new dimension in NIR-Ⅱ imaging.

基于三维测量的无人艇自动靠泊引导方法研究

Automatic berthing guidance is an important aspect of automated ship technology to obtain the ship-shore position relationship.The current mainstream measurement methods for ship-shore position relationships are based on radar,multisensor fusion,and visual detection technologies.This paper proposes an automated ship berthing guidance method based on three-dimensional(3D)target measurement and compares it with a single-target recognition method using a binocular camera.An improved deep object pose estimation(DOPE)network is used in this method to predict the pixel coordinates of the two-dimensional(2D)keypoints of the shore target in the image.The pixel coordinates are then converted into 3D coordinates through the camera imaging principle,and an algorithm for calculating the relationship between the ship and the shore is proposed.Experiments were conducted on the improved DOPE network and the actual ship guidance performance to verify the effectiveness of the method.Results show that the proposed method with a monocular camera has high stability and accuracy and can meet the requirements of automatic berthing.

GENERAL COUPLED MEAN-FIELD REFLECTED FORWARD-BACKWARD STOCHASTIC DIFFERENTIAL EQUATIONS

In this paper we consider general coupled mean-field reflected forward-backward stochastic differential equations(FBSDEs),whose coefficients not only depend on the solution but also on the law of the solution.The first part of the paper is devoted to the existence and the uniqueness of solutions for such general mean-field reflected backward stochastic differential equations(BSDEs)under Lipschitz conditions,and for the one-dimensional case a comparison theorem is studied.With the help of this comparison result,we prove the existence of the solution for our mean-field reflected forward-backward stochastic differential equation under continuity assumptions.It should be mentioned that,under appropriate assumptions,we prove the uniqueness of this solution as well as that of a comparison theorem for mean-field reflected FBSDEs in a non-trivial manner.