The India–Eurasia collision has produced a number of Cenozoic deep intracontinental basins,which bear important information for revealing the far-afield responses to the remote collision.Despite their significance,th...The India–Eurasia collision has produced a number of Cenozoic deep intracontinental basins,which bear important information for revealing the far-afield responses to the remote collision.Despite their significance,their subsiding mechanism remains the subject of debate,with end-member models attributing it to either orogenic or sedimentary load.In this study,we conduct flexural subsidence modeling with a two-dimensional finite elastic plate model on the Hotan-Mazatagh section along the southern Tarim Basin,which defines a key region in the foreland of the West Kunlun Orogen,along the NW margin of the Tibetan Plateau.The modeling results indicate that the orogenic load of West Kunlun triggers the southern Tarim Basin to subside by up to less than ~6 km,with its impact weakening towards the basin interiors until ~230 km north from the Karakax fault.The sedimentary load,consisting of Cenozoic strata,forces the basin to subside by ~2 to~7 km.In combination with the retreat of the proto-Paratethys Sea and the paleogeographic reorganization of the Tarim Basin,we propose that surface processes,in particular a shift from an exorheic to an endorheic drainage system associated with the consequent thick sedimentary load,played a decisive role in forming deep intracontinental basins in the context of the India-Eurasia collision.展开更多
Based on well horizon calibration,the typical seismic profiles in southwestern Tarim Basin were interpreted systematically,regional geological sections were established,and the regional denudation thickness of each te...Based on well horizon calibration,the typical seismic profiles in southwestern Tarim Basin were interpreted systematically,regional geological sections were established,and the regional denudation thickness of each tectonic period was restored.On this basis,the plane morphology maps of ancient structures of the Cambrian pre-salt dolomites in different periods were compiled,and the spatial distribution,development,evolution and migration of paleo-uplift in the late Early Paleozoic were analyzed.In the late Early Paleozoic,there existed a unified regional paleo-uplift widely distributed in southwestern Tarim Basin,which is called the southwestern Tarim plaeo-uplift.The“Tarim SW paleo-uplift”and“Hetian paleo-uplift”proposed in previous literatures are not independent,but the result of the spatio-temporal migration and evolution of the southwestern Tarim paleo-uplift identified in this paper.The southwestern Tarim paleo-uplift emerged at the end of Middle Ordovician,and took its initial shape with increased amplitude in the Late Ordovician.During the Silurian,the southwestern Tarim paleo-uplift rose steadily and expanded rapidly to the east,incorporating Pishan-Hetian and other areas,with the structural high locating in the Pishan-Hetian area.During the Devonian,the southwestern Tarim paleo-uplift began to shrink gradually,to a limited range in the Pishan-Hetian area in the southern part of the basin.During the Carboniferous,the southwestern Tarim paleo-uplift became an underwater uplift,that is,the paleo-uplift gradually died out.The southwestern Tarim paleo-uplift belongs to the forebulge of the southwestern Tarim foreland basin in the late Early Paleozoic,and its formation and evolution are related to the early Paleozoic orogeny of the West Kunlun orogenic belt in the south of the Tarim Basin.The migration of the southwestern Tarim paleo-uplift from the northwestern part of the southwestern Tarim Basin to the Pishan-Hetian area indicates the early Paleozoic orogenic process of the West Kunlun orogenic belt,which started in the western section at the end of Middle Ordovician and extended from west to east in a“scissor”style.The migration and evolution of the southwestern Tarim paleo-uplift controlled the development of unconformities at the end of Middle Ordovician,the end of Late Ordovician,and the end of Middle Devonian,and the spatial distribution of dissolved fracture-cave reservoirs in weathered crust below the unconformities in the southwest of Tarim Basin.The migration of the structural high of the southwestern Tarim paleo-uplift also played an important role in controlling the development of dissolved fracture-cave reservoirs in weathered crust.展开更多
病毒灭活是利用物理或化学方法使病毒失去感染性的过程。病毒的灭活效率常受到病毒特性、灭活剂种类、灭活目的等多个因素的影响。通常病毒特性和病毒灭活后的用途决定了灭活剂的选择,疫苗研制需病毒完全灭活的同时保持病毒保护性抗原...病毒灭活是利用物理或化学方法使病毒失去感染性的过程。病毒的灭活效率常受到病毒特性、灭活剂种类、灭活目的等多个因素的影响。通常病毒特性和病毒灭活后的用途决定了灭活剂的选择,疫苗研制需病毒完全灭活的同时保持病毒保护性抗原表位结构完整,以诱导有效的宿主免疫反应;分子生物学检测则需要病毒基因组完整等。因此选择适宜的灭活剂对高致病性病原进行灭活是病原分子诊断、血清学分析以及疫苗开发等后续工作的重要保障。目前越来越多的病毒灭活剂被开发和利用,本文选择5种实际工作中常用的化学类病毒灭活剂:甲醛(Formaldehyde)、β-丙内酯(β-propiolactone)、胍基离序盐(Guanidium based chao-tropicsalts)、补骨脂素(Psoralen)、过氧化氢(Hydrogenperoxide),对其灭活机理、病毒灭活特点以及灭活病毒在后续工作中的应用进行如下概述。展开更多
基金funded by the National Natural Science Foundation of China(Grant Nos.U22B6002,41972217 and 42002219)the Second Tibetan Plateau Scientific Expedition and Research of China(Grant No.2019QZKK0708)。
文摘The India–Eurasia collision has produced a number of Cenozoic deep intracontinental basins,which bear important information for revealing the far-afield responses to the remote collision.Despite their significance,their subsiding mechanism remains the subject of debate,with end-member models attributing it to either orogenic or sedimentary load.In this study,we conduct flexural subsidence modeling with a two-dimensional finite elastic plate model on the Hotan-Mazatagh section along the southern Tarim Basin,which defines a key region in the foreland of the West Kunlun Orogen,along the NW margin of the Tibetan Plateau.The modeling results indicate that the orogenic load of West Kunlun triggers the southern Tarim Basin to subside by up to less than ~6 km,with its impact weakening towards the basin interiors until ~230 km north from the Karakax fault.The sedimentary load,consisting of Cenozoic strata,forces the basin to subside by ~2 to~7 km.In combination with the retreat of the proto-Paratethys Sea and the paleogeographic reorganization of the Tarim Basin,we propose that surface processes,in particular a shift from an exorheic to an endorheic drainage system associated with the consequent thick sedimentary load,played a decisive role in forming deep intracontinental basins in the context of the India-Eurasia collision.
基金Supported by the National Science and Technology Major Project(2017ZX005-008-01)Tarim Oilfield Company Project(041014120098).
文摘Based on well horizon calibration,the typical seismic profiles in southwestern Tarim Basin were interpreted systematically,regional geological sections were established,and the regional denudation thickness of each tectonic period was restored.On this basis,the plane morphology maps of ancient structures of the Cambrian pre-salt dolomites in different periods were compiled,and the spatial distribution,development,evolution and migration of paleo-uplift in the late Early Paleozoic were analyzed.In the late Early Paleozoic,there existed a unified regional paleo-uplift widely distributed in southwestern Tarim Basin,which is called the southwestern Tarim plaeo-uplift.The“Tarim SW paleo-uplift”and“Hetian paleo-uplift”proposed in previous literatures are not independent,but the result of the spatio-temporal migration and evolution of the southwestern Tarim paleo-uplift identified in this paper.The southwestern Tarim paleo-uplift emerged at the end of Middle Ordovician,and took its initial shape with increased amplitude in the Late Ordovician.During the Silurian,the southwestern Tarim paleo-uplift rose steadily and expanded rapidly to the east,incorporating Pishan-Hetian and other areas,with the structural high locating in the Pishan-Hetian area.During the Devonian,the southwestern Tarim paleo-uplift began to shrink gradually,to a limited range in the Pishan-Hetian area in the southern part of the basin.During the Carboniferous,the southwestern Tarim paleo-uplift became an underwater uplift,that is,the paleo-uplift gradually died out.The southwestern Tarim paleo-uplift belongs to the forebulge of the southwestern Tarim foreland basin in the late Early Paleozoic,and its formation and evolution are related to the early Paleozoic orogeny of the West Kunlun orogenic belt in the south of the Tarim Basin.The migration of the southwestern Tarim paleo-uplift from the northwestern part of the southwestern Tarim Basin to the Pishan-Hetian area indicates the early Paleozoic orogenic process of the West Kunlun orogenic belt,which started in the western section at the end of Middle Ordovician and extended from west to east in a“scissor”style.The migration and evolution of the southwestern Tarim paleo-uplift controlled the development of unconformities at the end of Middle Ordovician,the end of Late Ordovician,and the end of Middle Devonian,and the spatial distribution of dissolved fracture-cave reservoirs in weathered crust below the unconformities in the southwest of Tarim Basin.The migration of the structural high of the southwestern Tarim paleo-uplift also played an important role in controlling the development of dissolved fracture-cave reservoirs in weathered crust.
文摘病毒灭活是利用物理或化学方法使病毒失去感染性的过程。病毒的灭活效率常受到病毒特性、灭活剂种类、灭活目的等多个因素的影响。通常病毒特性和病毒灭活后的用途决定了灭活剂的选择,疫苗研制需病毒完全灭活的同时保持病毒保护性抗原表位结构完整,以诱导有效的宿主免疫反应;分子生物学检测则需要病毒基因组完整等。因此选择适宜的灭活剂对高致病性病原进行灭活是病原分子诊断、血清学分析以及疫苗开发等后续工作的重要保障。目前越来越多的病毒灭活剂被开发和利用,本文选择5种实际工作中常用的化学类病毒灭活剂:甲醛(Formaldehyde)、β-丙内酯(β-propiolactone)、胍基离序盐(Guanidium based chao-tropicsalts)、补骨脂素(Psoralen)、过氧化氢(Hydrogenperoxide),对其灭活机理、病毒灭活特点以及灭活病毒在后续工作中的应用进行如下概述。
