[ Objective ] The paper was to understand distribution and damage of alien weed Mikania micramhaln in Huiyang District of China. [ Method ] The coverage, nearby water sources, surrounding plants and control status of ...[ Objective ] The paper was to understand distribution and damage of alien weed Mikania micramhaln in Huiyang District of China. [ Method ] The coverage, nearby water sources, surrounding plants and control status of M. micranthain under different habitats in Huiyang District were surveyed. [ Result] M. micrantha grew violently in the habitats of irrigation ditches, orchard, field edge and wasteland with the coverage ranging from 10% to 90%. It grew more seriously around water sources and was very likely to recur after control. The wild growth of M. micranthaln was harmful to local agriculture, forestry and fishery. The com- prehensive control measures combing artificial control, chemical control, biological control and ecological control should be adopted in different habitats. [ Conclusion] The study orovided basis for comorehensive control and invasion risk assessment of M. micranthain.展开更多
文摘R-spondins是包含凝血酶敏感蛋白1型重复序列[thrombospondin type 1 repeat(TSR-1)-containing proteins]的结构域家族,由四种分泌糖蛋白R-spondin 1-4组成。R-spondins通过富含亮氨酸的G蛋白偶联受体4/5/6(leucine-rish repeat-containing G-protein coupled receptor 4/5/6,LGR4/5/6)、细胞表面跨膜E3泛素连接酶ZNRF3[(zinc and ring finger 3)/RNF43(ring finger protein 43)]、硫酸乙酰肝素蛋白多糖(heparan sulfate proteoglycans,HSPGs)、包含GTPase激活蛋白1(IQ motif containing GTPase-activating protein 1,IQGAP1)来增强WNT/β-catenin信号通路,进而在人类胚胎发育、组织和器官稳定、干细胞自我更新等方面发挥作用。近年来研究发现R-spondins参与胚胎骨发育、成体骨形成和骨关节疾病的发生发展,对R-spondins的研究可能成为骨代谢疾病新的治疗方向。本文将对R-spondins增强WNT/β-catenin信号通路的相关机制及其对胚胎骨发育、成体骨形成、骨质疏松和骨关节炎相关疾病的影响做一综述。
基金Supported by Special Fund for Scientific Research in the Public Interest(201103027)Eleventh Five-Year National Science and Technology Support Project(2006BAD32B0103)
文摘[ Objective ] The paper was to understand distribution and damage of alien weed Mikania micramhaln in Huiyang District of China. [ Method ] The coverage, nearby water sources, surrounding plants and control status of M. micranthain under different habitats in Huiyang District were surveyed. [ Result] M. micrantha grew violently in the habitats of irrigation ditches, orchard, field edge and wasteland with the coverage ranging from 10% to 90%. It grew more seriously around water sources and was very likely to recur after control. The wild growth of M. micranthaln was harmful to local agriculture, forestry and fishery. The com- prehensive control measures combing artificial control, chemical control, biological control and ecological control should be adopted in different habitats. [ Conclusion] The study orovided basis for comorehensive control and invasion risk assessment of M. micranthain.
