CEACAM6在肿瘤中的作用机制及临床应用

癌胚抗原相关细胞黏附分子6(CEACAM6)属于癌胚抗原基因家族。近年来越来越多的证据显示,CEACAM6主要通过促进肿瘤的侵袭与转移,抑制肿瘤细胞的失巢凋亡,促进肿瘤血管生成和抑制肿瘤细胞间黏附作用等多方面机制参与肿瘤的发生、发展。本文对近年间国内外关于CEACAM6在肿瘤中的作用机制及临床应用作一综述,以期为CEACAM6应用于临床肿瘤治疗提供理论依据。

不同铸型对高铬铸铁磨球组织与性能的影响

通过对砂型、金属型和金属型覆砂三种铸造工艺生产的高铬铸铁磨球组织性能分析,发现砂型、金属型覆砂到金属型,高铬铸铁磨球的晶粒尺寸、碳化物尺寸逐次细化,碳化物分布依次均匀,并且热处理后三种工艺生产的高铬铸铁磨球硬度无明显差别。滚筒湿法磨损显示,金属型生产的高铬磨球损失重最低、金属型覆砂次之、砂型最多,依次增加比例约为5%。

CADI磨球异常组织分析与对策

采用标准金相技术并借助光学金相显微镜和扫描电镜,分别沿直径方向对铸态和淬火态磨球的微观组织进行了观察,对比分析了国内磨球与蒙古磨球由表层至心部的铸态组织和淬火态组织的差异,揭示了磨球表面激冷层相组成对磨球整体传热过程的作用机制。结果表明,从改善铸态组织和降低奥氏体稳定性两方面出发,提出了化学成分的调整方向,成功地解决了蒙古CADI磨球组织异常、心部淬不到、性能不达标等的生产难题。

关于新疆白杨河流域河长制工作实践探讨

新疆白杨河流域治理现状存在流域面临水资源短缺,上下游水资源分配差距较大,生活和农业水污染等问题亟待解决。通过总结国内流域治理经验,提出加强组织领导、减少农业用水、完善水资源制度及建立考核细则的方法,进一步完善河长制制度,为河长制制度在新疆河道治理的推广及应用提供宝贵的经验。

CO_(2)氧化1-丁烯脱氢制1 ,3-丁二烯反应热力学分析

通过热力学分析了CO_(2)氧化1-丁烯脱氢制1,3-丁二烯反应及反应限度。计算结果表明:目标反应在常温下不能发生,而在实验室最佳反应温度873.15 K下可逆进行;CO_(2)的引入促进了1-丁烯脱氢反应的进行;反应可以通过氧化脱氢反应的一步路径和直接脱氢与逆水煤气变换耦合的二步路径进行。并且,在热力学上异构化反应比氧化脱氢反应更容易发生,在无催化剂的自由竞争反应条件下,1-丁烯转化率可达93.68%,而1,3-丁二烯的收率仅能够达到54.64%,说明异构化反应是导致目标反应选择性低的原因。因此,从抑制异构化反应的角度进行催化剂的设计与开发,将有效提高该体系催化剂的催化性能。

Efficacy comparison between anterior subcutaneous and submuscular transposition of ulnar nerve in treating moderate-severe cubital tunnel syndrome

OBJECTIVE:To explore the optimal surgery in treating moderate-severe cubital tunnel(CuTS) syndrome by comparing the clinical efficiency of decompression and anterior subcutaneous transposition of ulnar nerve and decompression and anterior submuscular transposition of ulnar nerve,and to provide a theoretical basis for the appropriate surgical programs in treating moderate-severe Cu TS.METHODS:47 consecutive cases of moderate-severe Cu TS were surgically treated in our department from January 2014 to January 2017.All patients were divided into two groups by the doctor in our department.21 Cu TS cases were treated with decompression and anterior subcutaneous transposition of ulnar nerve,and other 26 cases were treated with decompression and anterior submuscular transposition of ulnar nerve.All the patients were followed 1 month,3 months and 6 months after operation to evaluate the recovery degree of ulnar nerve function and the clinical efficiency of the two methods was compared.RESULTS:Clinical symptoms of two groups were significant alleviated.There was no significant statistical difference between two groups in the clinical efficiency.CONCLUSION:Completely releasing of nerve truck is the most important step in treating mediate-severe Cu TS.Theclinical results of the two methods are similar,but the anterior subcutaneous transposition of ulnar nerve is more easy to operate and can be widely used.