AIM: To analyze the progress in diabetic retinopathy (DR) researches between 2000 and 2010 through bibliometric study. METHODS: Using ISI Web of Science database for statistical sources, we retrieved DR literatures du...AIM: To analyze the progress in diabetic retinopathy (DR) researches between 2000 and 2010 through bibliometric study. METHODS: Using ISI Web of Science database for statistical sources, we retrieved DR literatures during 2000-2010, analyzed 'the number of published articles per year, authors, source publications, subject category, document type, document language, institution and country/region' by bibliometric statistical methods. RESULTS: The total number of published articles that were retrieved for the years during 2000-2010 was 8590. DR researches changed as a linear upward trend, the main researches focused on ophthalmology, endocrine and metabolic diseases. Article was the main document type. Harvard University was the major research institution. CONCLUSION: There has achieved a significant increase in the number of ISI publications and collaborations in DR literatures from 2000 to 2010. With the rising of the number of diabetes in the world, diabetic retinopathy has become a focus of scientific researches.展开更多
Dear Editor Extracellular environment plays a role in regulating stem cell fates and three dimensional （3D） scaffolds can be utilized to mimic the internal environment in vitro. Currently, many types of cells have b...Dear Editor Extracellular environment plays a role in regulating stem cell fates and three dimensional （3D） scaffolds can be utilized to mimic the internal environment in vitro. Currently, many types of cells have been cultured in 3D conditions but only few studies have focused on reprogramming in a 3D environment. 3D culture systems provide circumstances that can better simulate native conditions which are comprised of distinctive cell morphology, oxygen levels, extracellular matrix secretion and concentration gradients of signaling factors （Keung et al., 2010; Gu et al., 2016）.展开更多
基金Liaoning Science and Technology Project,China(No.2009225005)
文摘AIM: To analyze the progress in diabetic retinopathy (DR) researches between 2000 and 2010 through bibliometric study. METHODS: Using ISI Web of Science database for statistical sources, we retrieved DR literatures during 2000-2010, analyzed 'the number of published articles per year, authors, source publications, subject category, document type, document language, institution and country/region' by bibliometric statistical methods. RESULTS: The total number of published articles that were retrieved for the years during 2000-2010 was 8590. DR researches changed as a linear upward trend, the main researches focused on ophthalmology, endocrine and metabolic diseases. Article was the main document type. Harvard University was the major research institution. CONCLUSION: There has achieved a significant increase in the number of ISI publications and collaborations in DR literatures from 2000 to 2010. With the rising of the number of diabetes in the world, diabetic retinopathy has become a focus of scientific researches.
文摘Dear Editor Extracellular environment plays a role in regulating stem cell fates and three dimensional （3D） scaffolds can be utilized to mimic the internal environment in vitro. Currently, many types of cells have been cultured in 3D conditions but only few studies have focused on reprogramming in a 3D environment. 3D culture systems provide circumstances that can better simulate native conditions which are comprised of distinctive cell morphology, oxygen levels, extracellular matrix secretion and concentration gradients of signaling factors （Keung et al., 2010; Gu et al., 2016）.
