AIM: To study the influence of HBcAg on the expression of transforming growth factor-beta 1 (TGF-131) in liver tissue of low-grade chronic hepatitis B (CHB) patients. METHODS: The expression of T(3F-β1 and HBc...AIM: To study the influence of HBcAg on the expression of transforming growth factor-beta 1 (TGF-131) in liver tissue of low-grade chronic hepatitis B (CHB) patients. METHODS: The expression of T(3F-β1 and HBcAg in liver samples from 93 low-grade CHB patients was detected by immunohistochemistry and valuated by semi-quantitative scoring. RESULTS: In the 93 low-grade CHB patients, HBcAg was expressed in cell plasma but not in the liver tissue. There was no significant difference between the two groups. CONCLUSION: The expression of TGF-β1 is not related with HBcAg expressed as plasma type in the tissues of low-grade CHB patients.展开更多
基金Supported by the Beijing Science and Technology Commission,No.H020920020290
文摘AIM: To study the influence of HBcAg on the expression of transforming growth factor-beta 1 (TGF-131) in liver tissue of low-grade chronic hepatitis B (CHB) patients. METHODS: The expression of T(3F-β1 and HBcAg in liver samples from 93 low-grade CHB patients was detected by immunohistochemistry and valuated by semi-quantitative scoring. RESULTS: In the 93 low-grade CHB patients, HBcAg was expressed in cell plasma but not in the liver tissue. There was no significant difference between the two groups. CONCLUSION: The expression of TGF-β1 is not related with HBcAg expressed as plasma type in the tissues of low-grade CHB patients.